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SNRPA small nuclear ribonucleoprotein polypeptide A [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu15951 NM_004596 Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu15951C NM_004596 Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol SNRPA
Entrez Gene ID 6626
Full Name small nuclear ribonucleoprotein polypeptide A
Synonyms Mud1, U1-A, U1A
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.1

Summary The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010].
Disorder

MIM: 182285

mRNA Protein Product Sequence Price Select
NM_004596, 295317321 NP_004587, 4759156 U1 small nuclear ribonucleoprotein A ORF Sequence $199.00
KEGG
hsa03040Spliceosome
hsa_M00351Spliceosome, U1-snRNP
WikiPathways
WP411mRNA processing
Reactome
REACT_71Gene Expression
REACT_467mRNA Splicing - Major Pathway
REACT_1735mRNA Splicing
REACT_125Processing of Capped Intron-Containing Pre-mRNA
Homo sapiens (human)SNRPANP_004587.1
Pan troglodytes (chimpanzee)SNRPAXP_512674.2
Macaca mulatta (Rhesus monkey)SNRPAXP_001098504.1
Canis lupus familiaris (dog)SNRPAXP_533663.2
Bos taurus (cattle)SNRPANP_001039504.1
Rattus norvegicus (Norway rat)SnrpaNP_001008304.1
Danio rerio (zebrafish)snrpaNP_955965.1
Drosophila melanogaster (fruit fly)snfNP_511045.1
Caenorhabditis elegansrnp-2NP_500504.1
Arabidopsis thaliana (thale cress)U1ANP_182280.1
Xenopus (Silurana) tropicalis (western clawed frog)snrpaNP_001016784.1
Process
IDNameEvidence
GO:0000398mRNA splicing, via spliceosomeIC
GO:0000398mRNA splicing, via spliceosomeTAS
GO:0008380RNA splicingTAS
GO:0010467gene expressionTAS
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005654nucleoplasmTAS
GO:0005681spliceosomal complexIDA
GO:0005685U1 snRNPIDA
GO:0005730nucleolusIDA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
Function
IDNameEvidence
GO:0000166nucleotide bindingIEA
GO:0003723RNA bindingIDA
GO:0005515protein bindingIPI
GO:0017069snRNA bindingIEA
GO:0044822poly(A) RNA bindingIDA
GeneCards SNRPA
PDB 3MUT, 3MUR, 3MUV, 3UD4, 3UCZ, 3IWN, 1VC0, 1NU4, 3HHN, 2OJ3, 1U6B, 3EGZ, 1DZ5, 3L3C, 3MUM, 1SJF, 3BO2, 1VC6, 3UD3, 1M5O, 3G8S, 1VC5, 1VBX, 1DRZ, 1SJ4, 3P49, 2U1A, 1VBY, 3CUL, 3G9C, 1VBZ, 3CUN, 1CX0, 1ZZN, 3UTR, 3K0J, 3R1H, 1AUD, 1OIA, 1M5V, 2A3J, 3R1L, 3IRW, 1FHT, 2OIH, 1M5P, 1M5K, 3PGW, 1VC7, 1URN, 3G96, 3G8T, 3BO3, 4C4W, 3MXH, 3IIN, 1SJ3, 3BO4, 2NZ4, 3UCU
UniProt P09012
Vega OTTHUMG00000182689
MIM 182285
Ensembl ENSG00000077312
HGNC 11151
HPRD 01658

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