• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


STAT4 signal transducer and activator of transcription 4 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001243835 Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15
NM_003151 Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15

*Business Day

Related Services

Gene Symbol STAT4
Entrez Gene ID 6775
Full Name signal transducer and activator of transcription 4
Synonyms SLEB11
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q32.2-q32.3

Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].
Disorder

MIM: 600558

{Rheumatoid arthritis, association with}, 180300 (3); {Systemic

mRNA Protein Product Sequence Price Select
NM_001243835, 345110659 NP_001230764, 345110660 signal transducer and activator of transcription 4 ORF Sequence $490.00
NM_003151, 345110658 NP_003142, 4507255 signal transducer and activator of transcription 4 ORF Sequence $490.00
KEGG
hsa04630Jak-STAT signaling pathway
hsa05161Hepatitis B
WikiPathways
WP2203TSLP Signaling Pathway
Pathway Interaction Database
il23pathwayIL23-mediated signaling events
il12_stat4pathwayIL12 signaling mediated by STAT4
cd8tcrdownstreampathwayDownstream signaling in naive CD8+ T cells
il27pathwayIL27-mediated signaling events
il12_2pathwayIL12-mediated signaling events
Homo sapiens (human)STAT4NP_003142.1
Pan troglodytes (chimpanzee)STAT4XP_003309420.1
Macaca mulatta (Rhesus monkey)STAT4XP_001082561.2
Canis lupus familiaris (dog)STAT4XP_536007.3
Bos taurus (cattle)STAT4XP_002685507.1
Mus musculus (house mouse)Stat4NP_035617.1
Rattus norvegicus (Norway rat)Stat4NP_001012226.1
Gallus gallus (chicken)STAT4XP_001231299.2
Danio rerio (zebrafish)stat4NP_001004510.1
GeneCards STAT4
UniProt Q14765
MIM 600558
Ensembl ENSG00000138378
HGNC 11365
HPRD 02779

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
signal transducer and activator of transcription 4
Names
signal transducer and activator of transcription 4

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.