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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


CDKL5 cyclin-dependent kinase-like 5 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu25494 NM_003159 Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant I, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu25494 NM_001037343 Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant II, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu25494 XM_006724511 PREDICTED: Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu53954 XM_005274584 PREDICTED: Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu53955 XM_005274585 PREDICTED: Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu25494C NM_003159 Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant I, mRNA. Customized vector On-demand 25 $1699.00
OHu25494C NM_001037343 Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant II, mRNA. Customized vector On-demand 25 $1699.00
OHu25494C XM_006724511 PREDICTED: Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant X3, mRNA. Customized vector On-demand 25 $1699.00
OHu53954C XM_005274584 PREDICTED: Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant X1, mRNA. Customized vector On-demand 25 $1699.00
OHu53955C XM_005274585 PREDICTED: Homo sapiens cyclin-dependent kinase-like 5 (CDKL5), transcript variant X2, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol CDKL5
Entrez Gene ID 6792
Full Name cyclin-dependent kinase-like 5
Synonyms EIEE2, ISSX, STK9
General protein information
Preferred Names
cyclin-dependent kinase-like 5
Names
cyclin-dependent kinase-like 5
serine/threonine kinase 9
serine/threonine-protein kinase 9
cyclin dependent kinase 5 transcript
NP_001032420.1
NP_003150.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp22

Summary This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].
Disorder

MIM: 300203

Epileptic encephalopathy, early infantile, 2, 300672 (3);

mRNA Protein Product Sequence Price Select
NM_001037343, 83367068 NP_001032420, 83367069 cyclin-dependent kinase-like 5 ORF Sequence $1500.00
NM_003159, 83367066 NP_003150, 4507281 cyclin-dependent kinase-like 5 ORF Sequence $1500.00
XM_005274584, 530421240 XP_005274641, 530421241 cyclin-dependent kinase-like 5 isoform X1 ORF Sequence $1500.00
XM_005274585, 530421242 XP_005274642, 530421243 cyclin-dependent kinase-like 5 isoform X2 ORF Sequence $750.00
XM_006724511, 578837947 XP_006724574, 578837948 cyclin-dependent kinase-like 5 isoform X3 ORF Sequence $1500.00
WikiPathways
WP2380BDNF signaling pathway
Homo sapiens (human)CDKL5NP_001032420.1
Pan troglodytes (chimpanzee)CDKL5XP_003317430.1
Macaca mulatta (Rhesus monkey)LOC693974XP_002808564.1
Canis lupus familiaris (dog)CDKL5XP_005641221.1
Bos taurus (cattle)CDKL5XP_002700425.2
Mus musculus (house mouse)Cdkl5NP_001019795.1
Rattus norvegicus (Norway rat)Cdkl5XP_006256971.1
Gallus gallus (chicken)CDKL5XP_425571.2
Danio rerio (zebrafish)cdkl5NP_001124243.1
Xenopus (Silurana) tropicalis (western clawed frog)cdkl5XP_004911815.1
Process
IDNameEvidence
GO:0001764neuron migrationISS
GO:0006468protein phosphorylationTAS
GO:0032855positive regulation of Rac GTPase activityISS
GO:0045773positive regulation of axon extensionISS
GO:0046777protein autophosphorylationIDA
GO:0050773regulation of dendrite developmentISS
GO:0050775positive regulation of dendrite morphogenesisISS
GO:0051726regulation of cell cycleIEA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0032587ruffle membraneISS
GO:0032839dendrite cytoplasmISS
GO:0044294dendritic growth coneISS
Function
IDNameEvidence
GO:0004672protein kinase activityIDA
GO:0004674protein serine/threonine kinase activityTAS
GO:0004693cyclin-dependent protein serine/threonine kinase activityIEA
GO:0005524ATP bindingIDA
GO:0016301kinase activityIDA
GO:0048365Rac GTPase bindingISS
GeneCards CDKL5
UniProt O76039
Vega OTTHUMG00000021214
MIM 300203
Ensembl ENSG00000008086
HGNC 11411
HPRD 02190

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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