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TCF4 transcription factor 4 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001083962 Homo sapiens transcription factor 4 (TCF4), transcript variant 1, mRNA. ORF Sequence $584.64
Peptide Services
Antibody Services
Protein Services
NM_001243226 Homo sapiens transcription factor 4 (TCF4), transcript variant 3, mRNA. ORF Sequence $673.38
Peptide Services
Antibody Services
Protein Services
NM_001243227 Homo sapiens transcription factor 4 (TCF4), transcript variant 4, mRNA. ORF Sequence $563.76
Peptide Services
Antibody Services
Protein Services
NM_001243228 Homo sapiens transcription factor 4 (TCF4), transcript variant 5, mRNA. ORF Sequence $589.86
Peptide Services
Antibody Services
Protein Services
NM_001243230 Homo sapiens transcription factor 4 (TCF4), transcript variant 6, mRNA. ORF Sequence $578.55
Peptide Services
Antibody Services
Protein Services
NM_001243231 Homo sapiens transcription factor 4 (TCF4), transcript variant 7, mRNA. ORF Sequence $544.62
Peptide Services
Antibody Services
Protein Services
NM_001243232 Homo sapiens transcription factor 4 (TCF4), transcript variant 8, mRNA. ORF Sequence $522.87
Peptide Services
Antibody Services
Protein Services
NM_001243233 Homo sapiens transcription factor 4 (TCF4), transcript variant 9, mRNA. ORF Sequence $468.06
Peptide Services
Antibody Services
Protein Services
NM_001243234 Homo sapiens transcription factor 4 (TCF4), transcript variant 10, mRNA. ORF Sequence $445.44
Peptide Services
Antibody Services
Protein Services
NM_001243235 Homo sapiens transcription factor 4 (TCF4), transcript variant 11, mRNA. ORF Sequence $441.96
Peptide Services
Antibody Services
Protein Services
NM_001243236 Homo sapiens transcription factor 4 (TCF4), transcript variant 12, mRNA. ORF Sequence $441.96
Peptide Services
Antibody Services
Protein Services
NM_003199 Homo sapiens transcription factor 4 (TCF4), transcript variant 2, mRNA. ORF Sequence $581.16
Peptide Services
Antibody Services
Protein Services


Gene Symbol TCF4
Entrez Gene ID 6925
Full Name transcription factor 4
Synonyms E2-2, ITF2, MGC149723, MGC149724, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

18

18q21.1

Summary This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Aug 2011].
Disorder

MIM: 602272

Pitt-Hopkins syndrome, 610954 (3)

mRNA Protein Product Sequence Price Select
NM_001083962, 145312266 NP_001077431, 145312267 transcription factor 4 isoform a Full Length $0.00
ORF Sequence $584.64
NM_001243226, 342672058 NP_001230155, 342672059 transcription factor 4 isoform c Full Length $0.00
ORF Sequence $673.38
NM_001243227, 342672060 NP_001230156, 342672061 transcription factor 4 isoform d Full Length $0.00
ORF Sequence $563.76
NM_001243228, 342672062 NP_001230157, 342672063 transcription factor 4 isoform e Full Length $0.00
ORF Sequence $589.86
NM_001243230, 342672064 NP_001230159, 342672065 transcription factor 4 isoform f Full Length $3506.85
ORF Sequence $578.55
NM_001243231, 342672066 NP_001230160, 342672067 transcription factor 4 isoform g Full Length $3489.30
ORF Sequence $544.62
NM_001243232, 342672068 NP_001230161, 342672069 transcription factor 4 isoform h Full Length $3504.60
ORF Sequence $522.87
NM_001243233, 342672070 NP_001230162, 342672071 transcription factor 4 isoform i Full Length $3472.65
ORF Sequence $468.06
NM_001243234, 342672072 NP_001230163, 342672073 transcription factor 4 isoform j Full Length $3312.45
ORF Sequence $445.44
NM_001243235, 342672074 NP_001230164, 342672075 transcription factor 4 isoform k Full Length $3307.05
ORF Sequence $441.96
NM_001243236, 342672076 NP_001230165, 342672077 transcription factor 4 isoform l Full Length $3314.25
ORF Sequence $441.96
NM_003199, 145386535 NP_003190, 4507399 transcription factor 4 isoform b Full Length $0.00
ORF Sequence $581.16
Pathway Interaction Database
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
ar_pathwayCoregulation of Androgen receptor activity
WikiPathways
WP363Wnt Signaling Pathway NetPath
WP2064Neural Crest Differentiation
Reactome
REACT_21402CDO in myogenesis
REACT_111045Developmental Biology
REACT_21303Myogenesis
Homo sapiens (human)TCF4NP_001077431.1
Pan troglodytes (chimpanzee)TCF4XP_003315984.1
Macaca mulatta (Rhesus monkey)TCF4XP_001084466.2
Canis lupus familiaris (dog)TCF4NP_001003268.1
Mus musculus (house mouse)Tcf4NP_038713.1
Rattus norvegicus (Norway rat)Tcf4NP_445821.1
GeneCards TCF4
PDB 2KWF
UniProt P15884, H3BTP3, B7Z5M6, E9PH57, B3KVA4, G0LNU5
MIM 602272
Ensembl ENSG00000196628
HGNC 11634
HPRD 03780

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
transcription factor 4
Names
transcription factor 4
SL3-3 enhancer factor 2
transcription factor 4, isoform D
transcription factor 4, isoform E
transcription factor 4, isoform R
immunoglobulin transcription factor 2
class B basic helix-loop-helix protein 19

Interactant

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