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TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001146274 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_001146283 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001146284 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001146285 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 5, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_001146286 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 6, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001198525 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 7, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001198526 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 8, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_001198527 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 9, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001198528 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 10, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001198529 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 11, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001198530 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 12, mRNA. GenEZ ORF Cloning On-demand $549.00 14
NM_001198531 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 13, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_030756 Homo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $849.00 20

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Gene Symbol TCF7L2
Entrez Gene ID 6934
Full Name transcription factor 7-like 2 (T-cell specific, HMG-box)
Synonyms TCF-4, TCF4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q25.3

Summary This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010].
Disorder

MIM: 602228

{Diabetes mellitus, type 2, susceptibility to}, 125853 (3)

mRNA Protein Product Sequence Price Select
NM_001146274, 226371763 NP_001139746, 226371764 transcription factor 7-like 2 isoform 1 ORF Sequence $700.00
NM_001146283, 226371619 NP_001139755, 226371620 transcription factor 7-like 2 isoform 3 ORF Sequence $550.00
NM_001146284, 226371622 NP_001139756, 226371623 transcription factor 7-like 2 isoform 4 ORF Sequence $550.00
NM_001146285, 226371624 NP_001139757, 226371625 transcription factor 7-like 2 isoform 5 ORF Sequence $700.00
NM_001146286, 226371626 NP_001139758, 226371627 transcription factor 7-like 2 isoform 6 ORF Sequence $550.00
NM_001198525, 309384249 NP_001185454, 309384250 transcription factor 7-like 2 isoform 7 ORF Sequence $550.00
NM_001198526, 309384251 NP_001185455, 309384252 transcription factor 7-like 2 isoform 8 ORF Sequence $700.00
NM_001198527, 309384253 NP_001185456, 309384254 transcription factor 7-like 2 isoform 9 ORF Sequence $550.00
NM_001198528, 309384256 NP_001185457, 309384257 transcription factor 7-like 2 isoform 10 ORF Sequence $550.00
NM_001198529, 309384258 NP_001185458, 309384259 transcription factor 7-like 2 isoform 11 ORF Sequence $550.00
NM_001198530, 309384260 NP_001185459, 309384261 transcription factor 7-like 2 isoform 12 ORF Sequence $400.00
NM_001198531, 309384262 NP_001185460, 309384263 transcription factor 7-like 2 isoform 13 ORF Sequence $550.00
NM_030756, 226371744 NP_110383, 170014696 transcription factor 7-like 2 isoform 2 ORF Sequence $700.00
KEGG
hsa05221Acute myeloid leukemia
hsa04310Wnt signaling pathway
hsa05215Prostate cancer
hsa04916Melanogenesis
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05213Endometrial cancer
hsa04520Adherens junction
hsa05217Basal cell carcinoma
hsa05210Colorectal cancer
hsa05200Pathways in cancer
hsa05216Thyroid cancer
Pathway Interaction Database
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
WikiPathways
WP2118Arrhythmogenic right ventricular cardiomyopathy
WP399Wnt Signaling Pathway and Pluripotency
WP53Id Signaling Pathway
Reactome
REACT_23974Incretin Synthesis, Secretion, and Inactivation
REACT_24019Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
REACT_1505Integration of energy metabolism
REACT_18325Regulation of Insulin Secretion
REACT_111217Metabolism
Homo sapiens (human)TCF7L2NP_001185455.1
Macaca mulatta (Rhesus monkey)LOC701759XP_001090054.2
Mus musculus (house mouse)Tcf7l2NP_001136394.1
Rattus norvegicus (Norway rat)Tcf7l2XP_001054844.2
Gallus gallus (chicken)TCF7L2NP_001193439.1
Danio rerio (zebrafish)tcf7l2NP_571334.1
Drosophila melanogaster (fruit fly)panNP_001014685.1

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
transcription factor 7-like 2
Names
transcription factor 7-like 2
hTCF-4
T-cell factor 4
T-cell factor-4 variant A
T-cell factor-4 variant B
T-cell factor-4 variant C
T-cell factor-4 variant D
T-cell factor-4 variant E
T-cell factor-4 variant F
T-cell factor-4 variant G
T-cell factor-4 variant H
T-cell factor-4 variant I
T-cell factor-4 variant J
T-cell factor-4 variant K
T-cell factor-4 variant L
T-cell factor-4 variant M
T-cell factor-4 variant X2
HMG box transcription factor 4
T-cell-specific transcription factor 4

Interactant



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