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ACTC1 actin, alpha, cardiac muscle 1 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19196D NM_005159 Homo sapiens actin, alpha, cardiac muscle 1 (ACTC1), mRNA. pcDNA3.1-C-(k)DYK In-stock 5-7 Starting from $99
OHu19196C NM_005159 Homo sapiens actin, alpha, cardiac muscle 1 (ACTC1), mRNA. Customized vector In-stock 5-7 Starting from $99

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Gene Symbol ACTC1
Entrez Gene ID 70
Full Name actin, alpha, cardiac muscle 1
Synonyms ACTC, ASD5, CMD1R, CMH11, LVNC4
General protein information
Preferred Names
actin, alpha cardiac muscle 1
actin, alpha cardiac muscle 1
Gene Type protein-coding
Organism Homo sapiens (human)



Summary Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008].

MIM: 102540

Cardiomyopathy, dilated, 1R, 613424 (3); Cardiomyopathy, familial

mRNA Protein Product Sequence Price Select
NM_005159, 113722123 NP_005150, 4885049 actin, alpha cardiac muscle 1 proprotein ORF Sequence $269.00
hsa04260Cardiac muscle contraction
hsa05414Dilated cardiomyopathy
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04261Adrenergic signaling in cardiomyocytes
WP289Myometrial Relaxation and Contraction Pathways
WP383Striated Muscle Contraction
WP2406Cardiac Progenitor Differentiation
Homo sapiens (human)ACTC1NP_005150.1
Pan troglodytes (chimpanzee)ACTC1XP_510285.1
Macaca mulatta (Rhesus monkey)ACTC1XP_001088409.2
Canis lupus familiaris (dog)ACTC1XP_535424.1
Bos taurus (cattle)ACTC1NP_001029757.1
Mus musculus (house mouse)Actc1NP_033738.1
Rattus norvegicus (Norway rat)Actc1NP_062056.1
Gallus gallus (chicken)ACTC1NP_001072949.1
Danio rerio (zebrafish)actc1aNP_001001409.2
Danio rerio (zebrafish)hm:zewp0073XP_002665778.1
Danio rerio (zebrafish)zgc:86709NP_001002066.1
Danio rerio (zebrafish)actc1bNP_571666.1
Arabidopsis thaliana (thale cress)ACT7NP_196543.1
Xenopus (Silurana) tropicalis (western clawed frog)actc1NP_989094.1
GO:0006200ATP catabolic processIDA
GO:0006915apoptotic processISS
GO:0030048actin filament-based movementIDA
GO:0030049muscle filament slidingTAS
GO:0030240skeletal muscle thin filament assemblyISS
GO:0031032actomyosin structure organizationISS
GO:0033275actin-myosin filament slidingIMP
GO:0042493response to drugIEA
GO:0043066negative regulation of apoptotic processIEA
GO:0045471response to ethanolIEA
GO:0055003cardiac myofibril assemblyISS
GO:0055008cardiac muscle tissue morphogenesisISS
GO:0060047heart contractionIMP
GO:0060048cardiac muscle contractionIEA
GO:0005615extracellular spaceIDA
GO:0005884actin filamentIDA
GO:0031674I bandISS
GO:0042643actomyosin, actin portionIDA
GO:0070062extracellular vesicular exosomeIDA
GO:0072562blood microparticleIDA
GO:0005524ATP bindingIDA
GO:0016887ATPase activityIDA
GO:0017022myosin bindingIDA
GO:0017022myosin bindingIPI
GeneCards ACTC1
UniProt B3KPP5, P68032
Vega OTTHUMG00000129675
MIM 102540
Ensembl ENSG00000159251
HGNC 143
HPRD 00015

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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