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TECTA tectorin alpha [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu25746 NM_005422 Homo sapiens tectorin alpha (TECTA), mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu45859 XM_005271653 PREDICTED: Homo sapiens tectorin alpha (TECTA), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 35 $3749.00
OHu25746C NM_005422 Homo sapiens tectorin alpha (TECTA), mRNA. Customized vector On-demand 35 $3749.00
OHu45859C XM_005271653 PREDICTED: Homo sapiens tectorin alpha (TECTA), transcript variant X1, mRNA. Customized vector On-demand 35 $3749.00

*Business Day

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Gene Symbol TECTA
Entrez Gene ID 7007
Full Name tectorin alpha
Synonyms DFNA12, DFNA8, DFNB21
General protein information
Preferred Names
alpha-tectorin
Names
alpha-tectorin
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q22-q24

Summary The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602574

Deafness, autosomal dominant 8/12, 601543 (3); Deafness, autosomal

mRNA Protein Product Sequence Price Select
NM_005422, 134268639 NP_005413, 134268640 alpha-tectorin precursor ORF Sequence $3500.00
XM_005271653, 530398337 XP_005271710, 530398338 alpha-tectorin isoform X1 ORF Sequence $3500.00
Homo sapiens (human)TECTANP_005413.2
Pan troglodytes (chimpanzee)TECTAXP_508823.2
Canis lupus familiaris (dog)TECTAXP_546475.2
Bos taurus (cattle)TECTAXP_003586997.1
Mus musculus (house mouse)TectaNP_033373.2
Rattus norvegicus (Norway rat)TectaNP_001100284.1
Gallus gallus (chicken)TECTAXP_004948075.1
Danio rerio (zebrafish)LOC561355XP_689855.5
Xenopus (Silurana) tropicalis (western clawed frog)LOC100490936XP_002935069.2
Process
IDNameEvidence
GO:0007160cell-matrix adhesionIEA
GO:0007605sensory perception of soundIEA
Component
IDNameEvidence
GO:0005578proteinaceous extracellular matrixIEA
GO:0005886plasma membraneIEA
GO:0031225anchored component of membraneIEA
GO:0070062extracellular vesicular exosomeIDA
GeneCards TECTA
UniProt O75443
Vega OTTHUMG00000149908
MIM 602574
Ensembl ENSG00000109927
HGNC 11720
HPRD 03985

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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