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TECTA tectorin alpha [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_005422 Homo sapiens tectorin alpha (TECTA), mRNA. ORF Sequence $2910.60
Peptide Services
Antibody Services
Protein Services


Gene Symbol TECTA
Entrez Gene ID 7007
Full Name tectorin alpha
Synonyms DFNA12, DFNA8, DFNB21
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q22-q24

Summary The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602574

Deafness, autosomal dominant 8/12, 601543 (3); Deafness, autosomal

mRNA Protein Product Sequence Price Select
NM_005422, 134268639 NP_005413, 134268640 alpha-tectorin precursor Full Length $2910.60
ORF Sequence $2910.60
Homo sapiens (human)TECTANP_005413.2
Pan troglodytes (chimpanzee)TECTAXP_508823.2
Canis lupus familiaris (dog)TECTAXP_546475.2
Bos taurus (cattle)TECTAXP_003586997.1
Mus musculus (house mouse)TectaNP_033373.2
Rattus norvegicus (Norway rat)TectaNP_001100284.1
Gallus gallus (chicken)TECTANP_990204.1
Danio rerio (zebrafish)LOC561355XP_689855.4
GeneCards TECTA
UniProt O75443
MIM 602574
Ensembl ENSG00000109927
HGNC 11720
HPRD 03985

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
alpha-tectorin
Names
alpha-tectorin

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