• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


TGFBI transforming growth factor, beta-induced, 68kDa [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu26539 NM_000358 Homo sapiens transforming growth factor, beta-induced, 68kDa (TGFBI), mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu26539C NM_000358 Homo sapiens transforming growth factor, beta-induced, 68kDa (TGFBI), mRNA. Customized vector On-demand 12-14 $329.00

*Business Day

Related Services

Gene Symbol TGFBI
Entrez Gene ID 7045
Full Name transforming growth factor, beta-induced, 68kDa
Synonyms BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q31

Summary This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008].
Disorder

MIM: 601692

Corneal dystrophy, Groenouw type I, 121900 (3); Corneal dystrophy,

mRNA Protein Product Sequence Price Select
NM_000358, 170650698 NP_000349, 4507467 transforming growth factor-beta-induced protein ig-h3 precursor ORF Sequence $700.00
Reactome
REACT_75925Amyloids
REACT_116125Disease
Homo sapiens (human)TGFBINP_000349.1
Pan troglodytes (chimpanzee)TGFBIXP_001169327.1
Macaca mulatta (Rhesus monkey)TGFBIXP_001111447.1
Canis lupus familiaris (dog)TGFBIXP_538640.3
Bos taurus (cattle)TGFBINP_001192331.1
Mus musculus (house mouse)TgfbiNP_033395.1
Rattus norvegicus (Norway rat)TgfbiNP_446254.1
Gallus gallus (chicken)TGFBINP_990367.1
Danio rerio (zebrafish)tgfbiNP_878282.1
Drosophila melanogaster (fruit fly)mfasNP_788650.1
Xenopus (Silurana) tropicalis (western clawed frog)tgfbiNP_001072329.1
Process
IDNameEvidence
GO:0001525angiogenesisIEP
GO:0002062chondrocyte differentiationIEA
GO:0007155cell adhesionIEA
GO:0007162negative regulation of cell adhesionTAS
GO:0007601visual perceptionIEA
GO:0008283cell proliferationTAS
GO:0030198extracellular matrix organizationIEA
GO:0050896response to stimulusIEA
Component
IDNameEvidence
GO:0005576extracellular regionTAS
GO:0005604basement membraneIEA
GO:0005615extracellular spaceIDA
GO:0005802trans-Golgi networkIDA
GO:0005886plasma membraneTAS
GO:0031012extracellular matrixIDA
GO:0031012extracellular matrixISS
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0005178integrin bindingTAS
GO:0005515protein bindingIPI
GO:0005518collagen bindingIPI
GO:0050840extracellular matrix bindingIEA
GeneCards TGFBI
PDB 1X3B, 2LTB, 2VXP, 2LTC
UniProt Q15582
Vega OTTHUMG00000163213
MIM 601692
Ensembl ENSG00000120708
HGNC 11771
HPRD 03409

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.