• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


TGFBR3 transforming growth factor, beta receptor III [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu15987 NM_003243 Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu16032 NM_001195683 Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu16032 NM_001195684 Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu15987 XM_006710867 PREDICTED: Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu15987 XM_006710868 PREDICTED: Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu15987C NM_003243 Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, mRNA. Customized vector On-demand 12-14 $329.00
OHu16032C NM_001195683 Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 2, mRNA. Customized vector On-demand 12-14 $329.00
OHu16032C NM_001195684 Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 3, mRNA. Customized vector On-demand 12-14 $329.00
OHu15987C XM_006710867 PREDICTED: Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu15987C XM_006710868 PREDICTED: Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant X2, mRNA. Customized vector On-demand 12-14 $329.00

*Business Day

Related Services

Gene Symbol TGFBR3
Entrez Gene ID 7049
Full Name transforming growth factor, beta receptor III
Synonyms BGCAN, betaglycan
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p33-p32

Summary This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010].
Disorder

MIM: 600742

mRNA Protein Product Sequence Price Select
NM_001195683, 307574690 NP_001182612, 307574691 transforming growth factor beta receptor type 3 isoform b precursor ORF Sequence $750.00
NM_001195684, 307574633 NP_001182613, 307574634 transforming growth factor beta receptor type 3 isoform b precursor ORF Sequence $750.00
NM_003243, 307574689 NP_003234, 56682966 transforming growth factor beta receptor type 3 isoform a precursor ORF Sequence $750.00
XM_006710867, 578799690 XP_006710930, 578799691 transforming growth factor beta receptor type 3 isoform X1 ORF Sequence $750.00
XM_006710868, 578799692 XP_006710931, 578799693 transforming growth factor beta receptor type 3 isoform X2 ORF Sequence $750.00
WikiPathways
WP366TGF-beta Receptor Signaling Pathway
WP560TGF Beta Signaling Pathway
Pathway Interaction Database
tgfbrpathwayTGF-beta receptor signaling
Homo sapiens (human)TGFBR3NP_003234.2
Pan troglodytes (chimpanzee)TGFBR3XP_513555.2
Macaca mulatta (Rhesus monkey)TGFBR3XP_001098070.1
Canis lupus familiaris (dog)TGFBR3XP_005621992.1
Bos taurus (cattle)TGFBR3XP_005204393.1
Mus musculus (house mouse)Tgfbr3NP_035708.2
Rattus norvegicus (Norway rat)Tgfbr3NP_058952.1
Gallus gallus (chicken)TGFBR3NP_989670.1
Danio rerio (zebrafish)tgfbr3XP_002662477.3
Xenopus (Silurana) tropicalis (western clawed frog)tgfbr3XP_002933852.2
Process
IDNameEvidence
GO:0001568blood vessel developmentIEA
GO:0001666response to hypoxiaIEA
GO:0001824blastocyst developmentIEA
GO:0001837epithelial to mesenchymal transitionIDA
GO:0001889liver developmentISS
GO:0003007heart morphogenesisISS
GO:0006955immune responseIMP
GO:0007179transforming growth factor beta receptor signaling pathwayIDA
GO:0007179transforming growth factor beta receptor signaling pathwayIMP
GO:0007181transforming growth factor beta receptor complex assemblyIEA
GO:0010633negative regulation of epithelial cell migrationIEA
GO:0010719negative regulation of epithelial to mesenchymal transitionIEA
GO:0016049cell growthISS
GO:0016477cell migrationISS
GO:0030509BMP signaling pathwayIDA
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathwayIEA
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayIEA
GO:0031100organ regenerationIEA
GO:0032354response to follicle-stimulating hormoneIDA
GO:0034695response to prostaglandin EIDA
GO:0034699response to luteinizing hormoneIDA
GO:0035556intracellular signal transductionIMP
GO:0043393regulation of protein bindingIEA
GO:0050680negative regulation of epithelial cell proliferationISS
GO:0051092positive regulation of NF-kappaB transcription factor activityIEA
GO:0051271negative regulation of cellular component movementIDA
GO:0055010ventricular cardiac muscle tissue morphogenesisISS
GO:0060021palate developmentISS
GO:0060038cardiac muscle cell proliferationISS
GO:0060216definitive hemopoiesisISS
GO:0060317cardiac epithelial to mesenchymal transitionIDA
GO:0060318definitive erythrocyte differentiationISS
GO:0060347heart trabecula formationISS
GO:0060389pathway-restricted SMAD protein phosphorylationIMP
Component
IDNameEvidence
GO:0005578proteinaceous extracellular matrixIEA
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceTAS
GO:0005783endoplasmic reticulumIEA
GO:0005887integral component of plasma membraneISS
GO:0009897external side of plasma membraneIDA
GO:0009986cell surfaceISS
GO:0034673inhibin-betaglycan-ActRII complexIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0005024transforming growth factor beta-activated receptor activityIDA
GO:0005114type II transforming growth factor beta receptor bindingIDA
GO:0005160transforming growth factor beta receptor bindingISS
GO:0005515protein bindingIPI
GO:0005515protein bindingIPI
GO:0005539glycosaminoglycan bindingISS
GO:0005539glycosaminoglycan bindingTAS
GO:0008201heparin bindingISS
GO:0015026coreceptor activityIDA
GO:0017134fibroblast growth factor bindingIEA
GO:0030165PDZ domain bindingISS
GO:0046332SMAD bindingIMP
GO:0048185activin bindingIEA
GO:0050431transforming growth factor beta bindingIDA
GO:0070123transforming growth factor beta receptor activity, type IIIIDA
GeneCards TGFBR3
UniProt Q03167
MIM 600742
Ensembl ENSG00000069702
HGNC 11774
HPRD 02846

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.