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TGM1 transglutaminase 1 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23436D NM_000359 Homo sapiens transglutaminase 1 (TGM1), mRNA. pcDNA3.1-C-(k)DYK In-stock 5-7 Starting from $99
OHu23436C NM_000359 Homo sapiens transglutaminase 1 (TGM1), mRNA. Customized vector In-stock 5-7 Starting from $99

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Gene Symbol TGM1
Entrez Gene ID 7051
Full Name transglutaminase 1
Synonyms ARCI1, ICR2, KTG, LI, LI1, TGASE, TGK
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq, Jul 2008].

MIM: 190195

Ichthyosis, lamellar, autosomal recessive, 242300 (3); Ichthyosiform

mRNA Protein Product Sequence Price Select
NM_000359, 110611244 NP_000350, 4507475 protein-glutamine gamma-glutamyltransferase K ORF Sequence $660.00
Homo sapiens (human)TGM1NP_000350.1
Pan troglodytes (chimpanzee)TGM1XP_001169496.3
Macaca mulatta (Rhesus monkey)TGM1XP_001113577.1
Canis lupus familiaris (dog)TGM1NP_001003079.1
Bos taurus (cattle)TGM1NP_001010991.1
Mus musculus (house mouse)Tgm1NP_001155187.1
Rattus norvegicus (Norway rat)Tgm1NP_113847.1
Danio rerio (zebrafish)LOC100334173XP_002665624.2
Danio rerio (zebrafish)tgm1l4NP_001025267.1
Danio rerio (zebrafish)LOC793448XP_001331914.1
Danio rerio (zebrafish)si:ch1073-138d10.2XP_005169495.1
Danio rerio (zebrafish)tgm1l1XP_694950.3
Danio rerio (zebrafish)LOC100535918XP_003201279.2
Danio rerio (zebrafish)tgm1l2XP_001332075.5
Drosophila melanogaster (fruit fly)TgNP_609174.1
Xenopus (Silurana) tropicalis (western clawed frog)tgm1XP_002939073.1
GO:0006464cellular protein modification processNAS
GO:0009887organ morphogenesisIEA
GO:0018149peptide cross-linkingIEA
GO:0030216keratinocyte differentiationIDA
GO:0043163cell envelope organizationTAS
GO:0001533cornified envelopeTAS
GO:0005913cell-cell adherens junctionIEA
GO:0031224intrinsic component of membraneIDA
GO:0070062extracellular vesicular exosomeIDA
GO:0003810protein-glutamine gamma-glutamyltransferase activityIDA
GO:0005515protein bindingIPI
GO:0046872metal ion bindingIEA
GeneCards TGM1
UniProt P22735
Vega OTTHUMG00000029329
MIM 190195
Ensembl ENSG00000092295
HGNC 11777
HPRD 01824

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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