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TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_005077 Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15
XM_005252151 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_005252152 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_005252153 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_005252154 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_005252155 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_005252156 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X6, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_005252162 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X12, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_005252163 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X13, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_006717258 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X14, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_006717259 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X15, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_006717260 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X16, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_006717261 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X17, mRNA. GenEZ ORF Cloning On-demand $849.00 20
XM_006717262 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X18, mRNA. GenEZ ORF Cloning On-demand $899.00 20
XM_006717263 PREDICTED: Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant X19, mRNA. GenEZ ORF Cloning On-demand $899.00 20

*Business Day

Related Services

Gene Symbol TLE1
Entrez Gene ID 7088
Full Name transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Synonyms ESG, ESG1, GRG1
General protein information
Preferred Names
transducin-like enhancer protein 1
Names
transducin-like enhancer protein 1
e(Sp1) homolog
enhancer of split groucho 1
enhancer of split groucho-like protein 1
transducin-like enhancer of split 1, homolog of Drosophila E(sp1)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q21.32

Summary
Disorder

MIM: 600189

mRNA Protein Product Sequence Price Select
NM_005077, 34147712 NP_005068, 21541824 transducin-like enhancer protein 1 ORF Sequence $660.00
XM_005252151, 530391450 XP_005252208, 530391451 transducin-like enhancer protein 1 isoform X1 ORF Sequence $750.00
XM_005252152, 530391452 XP_005252209, 530391453 transducin-like enhancer protein 1 isoform X2 ORF Sequence $750.00
XM_005252153, 530391454 XP_005252210, 530391455 transducin-like enhancer protein 1 isoform X3 ORF Sequence $750.00
XM_005252154, 530391456 XP_005252211, 530391457 transducin-like enhancer protein 1 isoform X4 ORF Sequence $750.00
XM_005252155, 530391458 XP_005252212, 530391459 transducin-like enhancer protein 1 isoform X5 ORF Sequence $750.00
XM_005252156, 530391460 XP_005252213, 530391461 transducin-like enhancer protein 1 isoform X6 ORF Sequence $750.00
XM_005252162, 530391472 XP_005252219, 530391473 transducin-like enhancer protein 1 isoform X12 ORF Sequence $700.00
XM_005252163, 530391474 XP_005252220, 530391475 transducin-like enhancer protein 1 isoform X13 ORF Sequence $700.00
XM_006717258, 578817823 XP_006717321, 578817824 transducin-like enhancer protein 1 isoform X14 ORF Sequence $750.00
XM_006717259, 578817825 XP_006717322, 578817826 transducin-like enhancer protein 1 isoform X15 ORF Sequence $700.00
XM_006717260, 578817827 XP_006717323, 578817828 transducin-like enhancer protein 1 isoform X16 ORF Sequence $700.00
XM_006717261, 578817829 XP_006717324, 578817830 transducin-like enhancer protein 1 isoform X17 ORF Sequence $700.00
XM_006717262, 578817831 XP_006717325, 578817832 transducin-like enhancer protein 1 isoform X18 ORF Sequence $750.00
XM_006717263, 578817833 XP_006717326, 578817834 transducin-like enhancer protein 1 isoform X19 ORF Sequence $750.00
WikiPathways
WP61Delta-Notch Signaling Pathway
Pathway Interaction Database
ps1pathwayPresenilin action in Notch and Wnt signaling
hes_heypathwayNotch-mediated HES/HEY network
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
Reactome
REACT_299Signaling by NOTCH
REACT_11045Signaling by Wnt
REACT_111102Signal Transduction
REACT_116125Disease
REACT_118859Signaling by NOTCH1
REACT_118780NOTCH1 Intracellular Domain Regulates Transcription
REACT_160248Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
REACT_160099FBXW7 Mutants and NOTCH1 in Cancer
REACT_160214Signaling by NOTCH1 in Cancer
REACT_160082Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
REACT_160133Signaling by NOTCH1 HD Domain Mutants in Cancer
REACT_160301Signaling by NOTCH1 PEST Domain Mutants in Cancer
REACT_200731deactivation of the beta-catenin transactivating complex
REACT_200777TCF dependent signaling in response to WNT
REACT_200753formation of the beta-catenin:TCF transactivating complex
Homo sapiens (human)TLE1NP_005068.2
Pan troglodytes (chimpanzee)LOC464546XP_003312170.1
Macaca mulatta (Rhesus monkey)TLE1XP_001104021.1
Canis lupus familiaris (dog)TLE1XP_533516.3
Mus musculus (house mouse)Tle1NP_035729.3
Rattus norvegicus (Norway rat)Tle1NP_001166904.1
Gallus gallus (chicken)TLE1XP_004949238.1
Xenopus (Silurana) tropicalis (western clawed frog)tle1NP_001163974.1
Process
IDNameEvidence
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0006351transcription, DNA-templatedIEA
GO:0007165signal transductionTAS
GO:0007219Notch signaling pathwayTAS
GO:0007275multicellular organismal developmentTAS
GO:0009887organ morphogenesisTAS
GO:0010628positive regulation of gene expressionIMP
GO:0016055Wnt signaling pathwayIEA
GO:0030178negative regulation of Wnt signaling pathwayNAS
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signalingIDA
GO:0045892negative regulation of transcription, DNA-templatedIDA
GO:2000811negative regulation of anoikisIMP
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005634nucleusIMP
GO:0005654nucleoplasmTAS
GO:0005667transcription factor complexIEA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolIMP
Function
IDNameEvidence
GO:0001106RNA polymerase II transcription corepressor activityIDA
GO:0003682chromatin bindingIEA
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingIDA
GO:0008134transcription factor bindingIPI
GeneCards TLE1
PDB 4OM2, 4OM3, 2CE8, 1GXR, 2CE9
UniProt Q04724
Vega OTTHUMG00000021008
MIM 600189
Ensembl ENSG00000196781
HGNC 11837
HPRD 02557

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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