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TNNI3 troponin I type 3 (cardiac) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000363 Homo sapiens troponin I type 3 (cardiac) (TNNI3), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

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Gene Symbol TNNI3
Entrez Gene ID 7137
Full Name troponin I type 3 (cardiac)
Synonyms CMD1FF, CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI
Gene Type protein-coding
Organism Homo sapiens (human)



Summary Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008].

MIM: 191044

Cardiomyopathy, familial hypertrophic, 7, 613690 (3); Cardiomyopathy,

mRNA Protein Product Sequence Price Select
NM_000363, 151101269 NP_000354, 151101270 troponin I, cardiac muscle ORF Sequence $159.00
hsa05414Dilated cardiomyopathy
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04260Cardiac muscle contraction
WP383Striated Muscle Contraction
REACT_17044Muscle contraction
REACT_16969Striated Muscle Contraction
Homo sapiens (human)TNNI3NP_000354.4
Pan troglodytes (chimpanzee)TNNI3XP_001134934.2
Macaca mulatta (Rhesus monkey)TNNI3XP_001085820.1
Canis lupus familiaris (dog)TNNI3NP_001003041.1
Bos taurus (cattle)TNNI3NP_001035607.1
Mus musculus (house mouse)Tnni3NP_033432.1
Rattus norvegicus (Norway rat)Tnni3NP_058840.1
GeneCards TNNI3
PDB 1LXF, 2L1R, 2KRD, 2KGB, 1J1E, 1MXL, 1J1D, 1OZS
UniProt Q6FGX2, P19429
MIM 191044
Ensembl ENSG00000129991
HGNC 11947
HPRD 11769

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
troponin I, cardiac muscle
troponin I, cardiac muscle


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