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Sequence in raw or FASTA format:

Database:

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TNNT2 troponin T type 2 (cardiac) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu24695 NM_001276347 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 7, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24894 NM_001001432 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24914 NM_001001431 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24970 NM_000364 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24695 NM_001001430 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu25008 NM_001276346 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 6, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu25054 NM_001276345 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24695 XM_006711508 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu34665 XM_006711509 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu34666 XM_006711510 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu34667 XM_006711511 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24914 XM_006711512 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu34668 XM_006711513 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu34669 XM_006711514 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X7, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24695C NM_001276347 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 7, mRNA. Customized vector On-demand 7-9 $209.00
OHu24894C NM_001001432 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 4, mRNA. Customized vector On-demand 7-9 $209.00
OHu24914C NM_001001431 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 3, mRNA. Customized vector On-demand 7-9 $209.00
OHu24970C NM_000364 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 1, mRNA. Customized vector On-demand 7-9 $209.00
OHu24695C NM_001001430 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 2, mRNA. Customized vector On-demand 7-9 $209.00
OHu25008C NM_001276346 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 6, mRNA. Customized vector On-demand 7-9 $209.00
OHu25054C NM_001276345 Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant 5, mRNA. Customized vector On-demand 7-9 $209.00
OHu24695C XM_006711508 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00
OHu34665C XM_006711509 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X2, mRNA. Customized vector On-demand 7-9 $209.00
OHu34666C XM_006711510 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X3, mRNA. Customized vector On-demand 7-9 $209.00
OHu34667C XM_006711511 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X4, mRNA. Customized vector On-demand 7-9 $209.00
OHu24914C XM_006711512 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X5, mRNA. Customized vector On-demand 7-9 $209.00
OHu34668C XM_006711513 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X6, mRNA. Customized vector On-demand 7-9 $209.00
OHu34669C XM_006711514 PREDICTED: Homo sapiens troponin T type 2 (cardiac) (TNNT2), transcript variant X7, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol TNNT2
Entrez Gene ID 7139
Full Name troponin T type 2 (cardiac)
Synonyms CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
General protein information
Preferred Names
troponin T, cardiac muscle
Names
troponin T, cardiac muscle
troponin T2, cardiac
cardiomyopathy, hypertrophic 2
cardiomyopathy, dilated 1D (autosomal dominant)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q32

Summary The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008].
Disorder

MIM: 191045

Cardiomyopathy, familial hypertrophic, 2, 115195 (3); Cardiomyopathy,

mRNA Protein Product Sequence Price Select
NM_000364, 446714949 NP_000355, 48255877 troponin T, cardiac muscle isoform 1 ORF Sequence $300.00
NM_001001430, 446714948 NP_001001430, 48255879 troponin T, cardiac muscle isoform 2 ORF Sequence $300.00
NM_001001431, 446715104 NP_001001431, 48255881 troponin T, cardiac muscle isoform 3 ORF Sequence $300.00
NM_001001432, 446715106 NP_001001432, 48255883 troponin T, cardiac muscle isoform 4 ORF Sequence $300.00
NM_001276345, 446715146 NP_001263274, 446715147 troponin T, cardiac muscle isoform 5 ORF Sequence $300.00
NM_001276346, 446715552 NP_001263275, 446715553 troponin T, cardiac muscle isoform 6 ORF Sequence $300.00
NM_001276347, 446715781 NP_001263276, 446715782 troponin T, cardiac muscle isoform 2 ORF Sequence $300.00
XM_006711508, 578801422 XP_006711571, 578801423 troponin T, cardiac muscle isoform X1 ORF Sequence $300.00
XM_006711509, 578801424 XP_006711572, 578801425 troponin T, cardiac muscle isoform X2 ORF Sequence $300.00
XM_006711510, 578801426 XP_006711573, 578801427 troponin T, cardiac muscle isoform X3 ORF Sequence $300.00
XM_006711511, 578801428 XP_006711574, 578801429 troponin T, cardiac muscle isoform X4 ORF Sequence $300.00
XM_006711512, 578801430 XP_006711575, 578801431 troponin T, cardiac muscle isoform X5 ORF Sequence $300.00
XM_006711513, 578801432 XP_006711576, 578801433 troponin T, cardiac muscle isoform X6 ORF Sequence $300.00
XM_006711514, 578801434 XP_006711577, 578801435 troponin T, cardiac muscle isoform X7 ORF Sequence $300.00
KEGG
hsa04260Cardiac muscle contraction
hsa05414Dilated cardiomyopathy
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04261Adrenergic signaling in cardiomyocytes
WikiPathways
WP383Striated Muscle Contraction
WP2406Cardiac Progenitor Differentiation
Reactome
REACT_16969Striated Muscle Contraction
REACT_17044Muscle contraction
Homo sapiens (human)TNNT2NP_001001432.1
Pan troglodytes (chimpanzee)TNNT2XP_001145598.1
Macaca mulatta (Rhesus monkey)TNNT2XP_002802032.1
Canis lupus familiaris (dog)TNNT2NP_001003012.1
Bos taurus (cattle)TNNT2NP_777196.1
Mus musculus (house mouse)Tnnt2NP_001123650.1
Rattus norvegicus (Norway rat)Tnnt2NP_036808.1
Gallus gallus (chicken)TNNT2NP_990780.1
Danio rerio (zebrafish)tnnt2aNP_690853.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100493699XP_004919786.1
Process
IDNameEvidence
GO:0006200ATP catabolic processIDA
GO:0006937regulation of muscle contractionIEA
GO:0008016regulation of heart contractionIMP
GO:0030049muscle filament slidingIDA
GO:0030049muscle filament slidingTAS
GO:0032780negative regulation of ATPase activityIDA
GO:0032781positive regulation of ATPase activityIDA
GO:0045214sarcomere organizationIEA
GO:0051592response to calcium ionIDA
GO:0051592response to calcium ionIMP
GO:0055009atrial cardiac muscle tissue morphogenesisIEA
GO:0055010ventricular cardiac muscle tissue morphogenesisIMP
Component
IDNameEvidence
GO:0005829cytosolTAS
GO:0005861troponin complexIDA
GO:0005865striated muscle thin filamentIDA
GO:0030017sarcomereTAS
Function
IDNameEvidence
GO:0003779actin bindingIDA
GO:0005200structural constituent of cytoskeletonIEA
GO:0005523tropomyosin bindingIDA
GO:0016887ATPase activityIDA
GO:0030172troponin C bindingIPI
GO:0031013troponin I bindingIPI
GeneCards TNNT2
UniProt P45379, Q15607
Vega OTTHUMG00000035733
MIM 191045
Ensembl ENSG00000118194
HGNC 11949
HPRD 01844

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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