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Sequence in raw or FASTA format:

Database:

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TRIO trio Rho guanine nucleotide exchange factor [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu25435 NM_007118 Homo sapiens trio Rho guanine nucleotide exchange factor (TRIO), mRNA. pcDNA3.1+-DYK On-demand -1 TBD
OHu39365 XM_006714495 PREDICTED: Homo sapiens trio Rho guanine nucleotide exchange factor (TRIO), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand -1 TBD
OHu25435C NM_007118 Homo sapiens trio Rho guanine nucleotide exchange factor (TRIO), mRNA. Customized vector On-demand -1 TBD
OHu39365C XM_006714495 PREDICTED: Homo sapiens trio Rho guanine nucleotide exchange factor (TRIO), transcript variant X2, mRNA. Customized vector On-demand -1 TBD

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Gene Symbol TRIO
Entrez Gene ID 7204
Full Name trio Rho guanine nucleotide exchange factor
Synonyms ARHGEF23, tgat
General protein information
Preferred Names
triple functional domain protein
Names
triple functional domain protein
PTPRF-interacting protein
triple functional domain (PTPRF interacting)
NP_009049.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5p15.2

Summary
Disorder

MIM: 601893

mRNA Protein Product Sequence Price Select
NM_007118, 45439358 NP_009049, 45439359 triple functional domain protein ORF Sequence $4500.00
XM_006714495, 578809983 XP_006714558, 578809984 triple functional domain protein isoform X2 ORF Sequence $3500.00
WikiPathways
WP2038Regulation of Microtubule Cytoskeleton
Pathway Interaction Database
rhoa_reg_pathwayRegulation of RhoA activity
rac1_reg_pathwayRegulation of RAC1 activity
Reactome
REACT_18266Axon guidance
REACT_19184GPCR downstream signaling
REACT_18407G alpha (12/13) signalling events
REACT_18283G alpha (q) signalling events
REACT_14797Signaling by GPCR
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_13638NRAGE signals death through JNK
REACT_11061Signalling by NGF
REACT_13776p75 NTR receptor-mediated signalling
REACT_11044Signaling by Rho GTPases
REACT_11051Rho GTPase cycle
REACT_22237Netrin-1 signaling
REACT_22351DCC mediated attractive signaling
REACT_111045Developmental Biology
REACT_111102Signal Transduction
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
Homo sapiens (human)TRIONP_009049.2
Pan troglodytes (chimpanzee)TRIOXP_517637.3
Macaca mulatta (Rhesus monkey)TRIOXP_002804369.1
Canis lupus familiaris (dog)TRIOXP_005639720.1
Mus musculus (house mouse)TrioNP_001074771.1
Rattus norvegicus (Norway rat)TrioXP_003749274.1
Gallus gallus (chicken)TRIOXP_419004.4
Danio rerio (zebrafish)trioaNP_001097996.1
Drosophila melanogaster (fruit fly)trioNP_651960.2
Caenorhabditis elegansunc-73NP_001021496.1
Xenopus (Silurana) tropicalis (western clawed frog)trioNP_001123393.1
Process
IDNameEvidence
GO:0006468protein phosphorylationIEA
GO:0007185transmembrane receptor protein tyrosine phosphatase signaling pathwayTAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0007411axon guidanceTAS
GO:0032321positive regulation of Rho GTPase activityIEA
GO:0043065positive regulation of apoptotic processTAS
GO:0043547positive regulation of GTPase activityTAS
GO:0048011neurotrophin TRK receptor signaling pathwayTAS
GO:0051056regulation of small GTPase mediated signal transductionTAS
GO:0097190apoptotic signaling pathwayTAS
Component
IDNameEvidence
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0004674protein serine/threonine kinase activityIEA
GO:0005085guanyl-nucleotide exchange factor activityTAS
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0019899enzyme bindingIEA
GeneCards TRIO
UniProt O75962
Vega OTTHUMG00000131057
MIM 601893
Ensembl ENSG00000038382
HGNC 12303
HPRD 03537

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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