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TUBA4A tubulin, alpha 4a [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_006000 Homo sapiens tubulin, alpha 4a (TUBA4A), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

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Gene Symbol TUBA4A
Entrez Gene ID 7277
Full Name tubulin, alpha 4a
Synonyms FLJ30169, H2-ALPHA, TUBA1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q35

Summary Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. [provided by RefSeq, Jul 2008].
Disorder

MIM: 191110

mRNA Protein Product Sequence Price Select
NM_006000, 17921988 NP_005991, 17921989 tubulin alpha-4A chain ORF Sequence $360.00
KEGG
hsa04540Gap junction
hsa05130Pathogenic Escherichia coli infection
hsa04145Phagosome
WikiPathways
WP2359Parkin-Ubiquitin Proteasomal System pathway
WP2272Pathogenic Escherichia coli infection
Reactome
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_152Cell Cycle, Mitotic
REACT_17004Chaperonin-mediated protein folding
REACT_15451Loss of proteins required for interphase microtubule organization####from the centrosome
REACT_16936Prefoldin mediated transfer of substrate to CCT/TriC
REACT_604Hemostasis
REACT_2203G2/M Transition
REACT_16956Formation of tubulin folding intermediates by CCT/TriC
REACT_115566Cell Cycle
REACT_318Platelet degranulation
REACT_15364Loss of Nlp from mitotic centrosomes
REACT_798Platelet activation, signaling and aggregation
REACT_17029Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REACT_21391Mitotic G2-G2/M phases
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_17015Metabolism of proteins
REACT_15479Centrosome maturation
REACT_16967Post-chaperonin tubulin folding pathway
REACT_16952Protein folding
Homo sapiens (human)TUBA4ANP_005991.1
Pan troglodytes (chimpanzee)TUBA4AXP_003309539.1
Macaca mulatta (Rhesus monkey)TUBA4AXP_001101117.1
Canis lupus familiaris (dog)TUBA4AXP_536077.2
Bos taurus (cattle)TUBA4ANP_001071626.1
Mus musculus (house mouse)Tuba4aNP_033473.1
Rattus norvegicus (Norway rat)Tuba4aNP_001007005.1
Gallus gallus (chicken)LOC100857214XP_003641691.1
Gallus gallus (chicken)LOC100857247XP_003641692.1
Danio rerio (zebrafish)tuba8l2NP_956985.1
GeneCards TUBA4A
UniProt P68366
MIM 191110
Ensembl ENSG00000127824
HGNC 12407
HPRD 01851

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
tubulin alpha-4A chain
Names
tubulin alpha-4A chain
tubulin H2-alpha
tubulin alpha-1 chain
tubulin, alpha 1 (testis specific)

Interactant



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