• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


TUBA4A tubulin, alpha 4a [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu09800 NM_001278552 Homo sapiens tubulin, alpha 4a (TUBA4A), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu21787 NM_006000 Homo sapiens tubulin, alpha 4a (TUBA4A), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu09800 XM_005246832 PREDICTED: Homo sapiens tubulin, alpha 4a (TUBA4A), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu09800C NM_001278552 Homo sapiens tubulin, alpha 4a (TUBA4A), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu21787C NM_006000 Homo sapiens tubulin, alpha 4a (TUBA4A), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu09800C XM_005246832 PREDICTED: Homo sapiens tubulin, alpha 4a (TUBA4A), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00

*Business Day

Related Services

Gene Symbol TUBA4A
Entrez Gene ID 7277
Full Name tubulin, alpha 4a
Synonyms H2-ALPHA, TUBA1
General protein information
Preferred Names
tubulin alpha-4A chain
Names
tubulin alpha-4A chain
tubulin H2-alpha
tubulin alpha-1 chain
tubulin, alpha 1 (testis specific)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q35

Summary Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013].
Disorder

MIM: 191110

mRNA Protein Product Sequence Price Select
NM_001278552, 514052658 NP_001265481, 514052659 tubulin alpha-4A chain isoform 2 ORF Sequence $550.00
NM_006000, 514052657 NP_005991, 17921989 tubulin alpha-4A chain isoform 1 ORF Sequence $360.00
XM_005246832, 530370915 XP_005246889, 530370916 tubulin alpha-4A chain isoform X1 ORF Sequence $550.00
KEGG
hsa05130Pathogenic Escherichia coli infection
hsa04540Gap junction
hsa04145Phagosome
WikiPathways
WP2359Parkin-Ubiquitin Proteasomal System pathway
WP2272Pathogenic Escherichia coli infection
Reactome
REACT_152Cell Cycle, Mitotic
REACT_2203G2/M Transition
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_15479Centrosome maturation
REACT_15364Loss of Nlp from mitotic centrosomes
REACT_15451Loss of proteins required for interphase microtubule organization####from the centrosome
REACT_798Platelet activation, signaling and aggregation
REACT_604Hemostasis
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_16936Prefoldin mediated transfer of substrate to CCT/TriC
REACT_17015Metabolism of proteins
REACT_16952Protein folding
REACT_17029Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REACT_16956Formation of tubulin folding intermediates by CCT/TriC
REACT_17004Chaperonin-mediated protein folding
REACT_16967Post-chaperonin tubulin folding pathway
REACT_21391Mitotic G2-G2/M phases
REACT_115566Cell Cycle
REACT_160315Regulation of PLK1 Activity at G2/M Transition
Homo sapiens (human)TUBA4ANP_005991.1
Pan troglodytes (chimpanzee)TUBA4AXP_003309539.1
Macaca mulatta (Rhesus monkey)TUBA4AXP_001101117.1
Canis lupus familiaris (dog)TUBA4AXP_536077.2
Bos taurus (cattle)TUBA4ANP_001071626.1
Mus musculus (house mouse)Tuba4aNP_033473.1
Rattus norvegicus (Norway rat)Tuba4aNP_001007005.1
Gallus gallus (chicken)LOC100857214XP_003641691.2
Danio rerio (zebrafish)tuba8l3NP_001003558.1
Danio rerio (zebrafish)tuba8l4NP_956479.1
Xenopus (Silurana) tropicalis (western clawed frog)tuba4bNP_001016694.1
Process
IDNameEvidence
GO:0000086G2/M transition of mitotic cell cycleTAS
GO:0000278mitotic cell cycleTAS
GO:0002576platelet degranulationTAS
GO:0006184GTP catabolic processIEA
GO:0006457protein foldingTAS
GO:0007017microtubule-based processIEA
GO:0007596blood coagulationTAS
GO:0030168platelet activationTAS
GO:0044267cellular protein metabolic processTAS
GO:0051084'de novo' posttranslational protein foldingTAS
GO:0051258protein polymerizationIEA
Component
IDNameEvidence
GO:0005576extracellular regionTAS
GO:0005829cytosolTAS
GO:0005874microtubuleIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0003924GTPase activityIEA
GO:0005200structural constituent of cytoskeletonIEA
GO:0005515protein bindingIPI
GO:0005525GTP bindingIEA
GeneCards TUBA4A
UniProt P68366
Vega OTTHUMG00000133126
MIM 191110
Ensembl ENSG00000127824
HGNC 12407
HPRD 01851

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.