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Sequence in raw or FASTA format:

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UMOD uromodulin [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu20652 NM_001278614 Homo sapiens uromodulin (UMOD), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu21261 NM_001008389 Homo sapiens uromodulin (UMOD), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu21261 NM_003361 Homo sapiens uromodulin (UMOD), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu49191 XM_006721085 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu21261 XM_006721086 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu21261 XM_006721087 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu21261 XM_006721088 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu49192 XM_006721089 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20652C NM_001278614 Homo sapiens uromodulin (UMOD), transcript variant 3, mRNA. Customized vector On-demand 12-14 $329.00
OHu21261C NM_001008389 Homo sapiens uromodulin (UMOD), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu21261C NM_003361 Homo sapiens uromodulin (UMOD), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OHu49191C XM_006721085 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu21261C XM_006721086 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OHu21261C XM_006721087 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00
OHu21261C XM_006721088 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X4, mRNA. Customized vector On-demand 7-9 $269.00
OHu49192C XM_006721089 PREDICTED: Homo sapiens uromodulin (UMOD), transcript variant X5, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol UMOD
Entrez Gene ID 7369
Full Name uromodulin
Synonyms ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP
General protein information
Preferred Names
uromodulin
Names
uromodulin
uromucoid
Tamm-Horsfall urinary glycoprotein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p12.3

Summary The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013].
Disorder

MIM: 191845

Hyperuricemic nephropathy, familial juvenile 1, 162000 (3);

mRNA Protein Product Sequence Price Select
NM_001008389, 519666792 NP_001008390, 56550049 uromodulin isoform a preproprotein ORF Sequence $700.00
NM_001278614, 519666793 NP_001265543, 519666794 uromodulin isoform b preproprotein ORF Sequence $700.00
NM_003361, 519666791 NP_003352, 59850812 uromodulin isoform a preproprotein ORF Sequence $700.00
XM_006721085, 578828647 XP_006721148, 578828648 uromodulin isoform X1 ORF Sequence $700.00
XM_006721086, 578828649 XP_006721149, 578828650 uromodulin isoform X2 ORF Sequence $700.00
XM_006721087, 578828651 XP_006721150, 578828652 uromodulin isoform X3 ORF Sequence $700.00
XM_006721088, 578828653 XP_006721151, 578828654 uromodulin isoform X4 ORF Sequence $700.00
XM_006721089, 578828655 XP_006721152, 578828656 uromodulin isoform X5 ORF Sequence $550.00
Homo sapiens (human)UMODNP_001265543.1
Pan troglodytes (chimpanzee)UMODXP_003954410.1
Macaca mulatta (Rhesus monkey)UMODXP_001086040.2
Canis lupus familiaris (dog)UMODNP_001003003.1
Bos taurus (cattle)UMODNP_776638.1
Mus musculus (house mouse)UmodNP_001265534.1
Rattus norvegicus (Norway rat)UmodNP_058778.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100491428XP_002932031.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100491925XP_002932034.2
Xenopus (Silurana) tropicalis (western clawed frog)LOC101731793XP_004918347.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC101731733XP_004918346.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100492097XP_004918349.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC101732035XP_004918350.1
Process
IDNameEvidence
GO:0006968cellular defense responseTAS
GO:0007157heterophilic cell-cell adhesionIDA
GO:0007159leukocyte cell-cell adhesionIDA
GO:0007588excretionIEA
GO:0008285negative regulation of cell proliferationTAS
GO:0010033response to organic substanceIEA
GO:0048878chemical homeostasisIEA
GO:0072218metanephric ascending thin limb developmentIEA
GO:0072221metanephric distal convoluted tubule developmentIEA
GO:0072233metanephric thick ascending limb developmentIEA
GO:1990266neutrophil migrationIDA
GO:2000021regulation of ion homeostasisIEA
Component
IDNameEvidence
GO:0000922spindle poleIDA
GO:0005615extracellular spaceIEA
GO:0005794Golgi apparatusIEA
GO:0016323basolateral plasma membraneIDA
GO:0016324apical plasma membraneIDA
GO:0019898extrinsic component of membraneTAS
GO:0031225anchored component of membraneIDA
GO:0031410cytoplasmic vesicleIEA
GO:0045121membrane raftIEA
GO:0060170ciliary membraneIEA
GO:0070062extracellular vesicular exosomeIDA
GO:0072372primary ciliumIDA
Function
IDNameEvidence
GO:0005509calcium ion bindingIEA
GO:0019864IgG bindingIDA
GeneCards UMOD
UniProt P07911
Vega OTTHUMG00000131488
MIM 191845
Ensembl ENSG00000169344
HGNC 12559
HPRD 11771

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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