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Sequence in raw or FASTA format:

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VLDLR very low density lipoprotein receptor [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu22485 NM_003383 Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu25103 NM_001018056 Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu42845 XM_006716864 PREDICTED: Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu42846 XM_006716865 PREDICTED: Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu22485C NM_003383 Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant 1, mRNA. Customized vector On-demand 12-14 $329.00
OHu25103C NM_001018056 Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant 2, mRNA. Customized vector On-demand 12-14 $329.00
OHu42845C XM_006716864 PREDICTED: Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu42846C XM_006716865 PREDICTED: Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant X2, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol VLDLR
Entrez Gene ID 7436
Full Name very low density lipoprotein receptor
Synonyms CARMQ1, CHRMQ1, VLDLRCH
General protein information
Preferred Names
very low-density lipoprotein receptor
Names
very low-density lipoprotein receptor
VLDL-R
VLDL receptor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9p24

Summary The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009].
Disorder

MIM: 192977

Cerebellar hypoplasia and mental retardation with or without

mRNA Protein Product Sequence Price Select
NM_001018056, 65301163 NP_001018066, 65301164 very low-density lipoprotein receptor isoform b precursor ORF Sequence $750.00
NM_003383, 65301166 NP_003374, 65301167 very low-density lipoprotein receptor isoform a precursor ORF Sequence $750.00
XM_006716864, 578816710 XP_006716927, 578816711 very low-density lipoprotein receptor isoform X1 ORF Sequence $750.00
XM_006716865, 578816712 XP_006716928, 578816713 very low-density lipoprotein receptor isoform X2 ORF Sequence $750.00
Pathway Interaction Database
reelinpathwayReelin signaling pathway
lis1pathwayLissencephaly gene (LIS1) in neuronal migration and development
Homo sapiens (human)VLDLRNP_003374.3
Pan troglodytes (chimpanzee)VLDLRXP_520460.3
Macaca mulatta (Rhesus monkey)VLDLRNP_001028079.1
Canis lupus familiaris (dog)VLDLRXP_533538.2
Bos taurus (cattle)VLDLRNP_776914.1
Mus musculus (house mouse)VldlrNP_038731.2
Rattus norvegicus (Norway rat)VldlrNP_037287.2
Gallus gallus (chicken)VLDLRNP_990560.1
Danio rerio (zebrafish)vldlrNP_957217.2
Drosophila melanogaster (fruit fly)LpR2NP_001097928.1
Drosophila melanogaster (fruit fly)LpR1NP_001262974.1
Caenorhabditis elegansT13C2.6NP_872023.2
Xenopus (Silurana) tropicalis (western clawed frog)vldlrXP_002934223.1
Process
IDNameEvidence
GO:0000122negative regulation of transcription from RNA polymerase II promoterISS
GO:0006869lipid transportIEA
GO:0006898receptor-mediated endocytosisIDA
GO:0007165signal transductionTAS
GO:0007399nervous system developmentTAS
GO:0007613memoryTAS
GO:0008203cholesterol metabolic processIEA
GO:0021517ventral spinal cord developmentIEA
GO:0034436glycoprotein transportIDA
GO:0034447very-low-density lipoprotein particle clearanceIDA
GO:0038026reelin-mediated signaling pathwayISS
GO:0045860positive regulation of protein kinase activityIEA
GO:1900006positive regulation of dendrite developmentISS
Component
IDNameEvidence
GO:0005886plasma membraneTAS
GO:0005905coated pitIEA
GO:0016020membraneIDA
GO:0016021integral component of membraneIEA
GO:0034361very-low-density lipoprotein particleIEA
GO:0043235receptor complexIDA
Function
IDNameEvidence
GO:0001948glycoprotein bindingIPI
GO:0005041low-density lipoprotein receptor activityTAS
GO:0005509calcium ion bindingIEA
GO:0005515protein bindingIPI
GO:0030229very-low-density lipoprotein particle receptor activityIDA
GO:0034185apolipoprotein bindingIDA
GO:0034185apolipoprotein bindingISS
GO:0034189very-low-density lipoprotein particle bindingIDA
GO:0034437glycoprotein transporter activityIDA
GO:0038025reelin receptor activityISS
GO:0048306calcium-dependent protein bindingIPI
GeneCards VLDLR
UniProt P98155, Q5VVF5
Vega OTTHUMG00000019447
MIM 192977
Ensembl ENSG00000147852
HGNC 12698
HPRD 01895

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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