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XPA xeroderma pigmentosum, complementation group A [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000380 Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $449.00 14

*Business Day

Related Services

Gene Symbol XPA
Entrez Gene ID 7507
Full Name xeroderma pigmentosum, complementation group A
Synonyms XP1, XPAC
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q22.3

Summary This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].
Disorder

MIM: 611153

Xeroderma pigmentosum, group A, 278700 (3)

mRNA Protein Product Sequence Price Select
NM_000380, 156564394 NP_000371, 4507937 DNA repair protein complementing XP-A cells ORF Sequence $300.00
KEGG
hsa03420Nucleotide excision repair
Reactome
REACT_311Dual incision reaction in GG-NER
REACT_2253Global Genomic NER (GG-NER)
REACT_216DNA Repair
REACT_1826Nucleotide Excision Repair
REACT_257Formation of incision complex in GG-NER
Homo sapiens (human)XPANP_000371.1
Pan troglodytes (chimpanzee)XPAXP_001156167.2
Macaca mulatta (Rhesus monkey)XPAXP_001114093.1
Canis lupus familiaris (dog)XPAXP_538745.2
Bos taurus (cattle)XPANP_001033770.1
Mus musculus (house mouse)XpaNP_035858.2
Rattus norvegicus (Norway rat)XpaNP_001100126.1
Gallus gallus (chicken)XPANP_990184.1
Danio rerio (zebrafish)xpaNP_956765.1
Drosophila melanogaster (fruit fly)XpacNP_476866.1
Caenorhabditis elegansxpa-1NP_492025.1
GeneCards XPA
PDB 2JNW, 1D4U, 1XPA
UniProt P23025
MIM 611153
Ensembl ENSG00000136936
HGNC 12814
HPRD 02045

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
DNA repair protein complementing XP-A cells
Names
DNA repair protein complementing XP-A cells
excision repair-controlling
xeroderma pigmentosum group A-complementing protein

Interactant



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