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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001100118 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 3, mRNA. ORF Sequence $301.89
Peptide Services
Antibody Services
Protein Services
NM_001100119 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 1, mRNA. ORF Sequence $301.89
Peptide Services
Antibody Services
Protein Services
NM_005432 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, mRNA. ORF Sequence $301.89
Peptide Services
Antibody Services
Protein Services


Gene Symbol XRCC3
Entrez Gene ID 7517
Full Name X-ray repair complementing defective repair in Chinese hamster cells 3
Synonyms CMM6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q32.3

Summary This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600675

{Melanoma, cutaneous malignant, susceptibility to, 6} (3); {Breast

mRNA Protein Product Sequence Price Select
NM_001100118, 153946426 NP_001093588, 153946427 DNA repair protein XRCC3 Full Length $743.27
ORF Sequence $301.89
NM_001100119, 153946429 NP_001093589, 153946430 DNA repair protein XRCC3 Full Length $770.53
ORF Sequence $301.89
NM_005432, 153946428 NP_005423, 4885659 DNA repair protein XRCC3 Full Length $759.80
ORF Sequence $301.89
KEGG
hsa03440Homologous recombination
WikiPathways
WP1984Integrated Breast Cancer Pathway
WP1601Fluoropyrimidine Activity
Homo sapiens (human)XRCC3NP_005423.1
Pan troglodytes (chimpanzee)XRCC3XP_003314577.1
Macaca mulatta (Rhesus monkey)XRCC3XP_001083970.1
Canis lupus familiaris (dog)XRCC3XP_003435154.1
Bos taurus (cattle)XRCC3NP_001071585.1
Mus musculus (house mouse)Xrcc3NP_083151.1
Rattus norvegicus (Norway rat)Xrcc3XP_002729772.1
Gallus gallus (chicken)XRCC3NP_001006489.1
Danio rerio (zebrafish)xrcc3NP_001013559.1
Drosophila melanogaster (fruit fly)spn-BNP_476740.1
Arabidopsis thaliana (thale cress)XRCC3NP_200554.1
GeneCards XRCC3
UniProt O43542, Q53XC8
MIM 600675
Ensembl ENSG00000126215
HGNC 12830
HPRD 07201

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
DNA repair protein XRCC3
Names
DNA repair protein XRCC3
X-ray repair cross-complementing protein 3

Interactant

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