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Sequence in raw or FASTA format:


Blast Method:


ZIC3 Zic family member 3 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18212D NM_003413 Homo sapiens Zic family member 3 (ZIC3), mRNA. pcDNA3.1-C-(k)DYK In-stock TBD Starting from $99
OHu18212C NM_003413 Homo sapiens Zic family member 3 (ZIC3), mRNA. Customized vector In-stock TBD Starting from $99

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Gene Symbol ZIC3
Entrez Gene ID 7547
Full Name Zic family member 3
Synonyms HTX, HTX1, VACTERLX, ZNF203
General protein information
Preferred Names
zinc finger protein ZIC 3
zinc finger protein ZIC 3
heterotaxy 1
zinc finger protein 203
zinc finger protein of the cerebellum 3
Zic family member 3 (odd-paired homolog, Drosophila)
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008].

MIM: 300265

Heterotaxy, visceral, 1, X-linked 306955 (3); Congenital heart

mRNA Protein Product Sequence Price Select
NM_003413, 194272159 NP_003404, 4507973 zinc finger protein ZIC 3 ORF Sequence $550.00
REACT_111045Developmental Biology
REACT_200812Transcriptional regulation of pluripotent stem cells
REACT_200759POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Homo sapiens (human)ZIC3NP_003404.1
Canis lupus familiaris (dog)ZIC3XP_549291.3
Bos taurus (cattle)ZIC3NP_001179742.1
Mus musculus (house mouse)Zic3NP_033601.2
Gallus gallus (chicken)ZIC3XP_420237.4
Danio rerio (zebrafish)zic3NP_001001950.1
Xenopus (Silurana) tropicalis (western clawed frog)zic3NP_001005691.1
GO:0001947heart loopingIMP
GO:0006351transcription, DNA-templatedIEA
GO:0007368determination of left/right symmetryIMP
GO:0009952anterior/posterior pattern specificationIEA
GO:0030154cell differentiationIEA
GO:0030324lung developmentIMP
GO:0035469determination of pancreatic left/right asymmetryIMP
GO:0035545determination of left/right asymmetry in nervous systemIEA
GO:0045893positive regulation of transcription, DNA-templatedISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0071907determination of digestive tract left/right asymmetryIMP
GO:0071910determination of liver left/right asymmetryIMP
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0005515protein bindingIPI
GO:0043565sequence-specific DNA bindingIDA
GO:0046872metal ion bindingIEA
GeneCards ZIC3
UniProt O60481
Vega OTTHUMG00000022525
MIM 300265
Ensembl ENSG00000156925
HGNC 12874
HPRD 02225

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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