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ZBTB16 zinc finger and BTB domain containing 16 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001018011 Homo sapiens zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 2, mRNA. ORF Sequence $586.38
Peptide Services
Antibody Services
Protein Services
NM_006006 Homo sapiens zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1, mRNA. ORF Sequence $586.38
Peptide Services
Antibody Services
Protein Services


Gene Symbol ZBTB16
Entrez Gene ID 7704
Full Name zinc finger and BTB domain containing 16
Synonyms PLZF, ZNF145
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q23.1

Summary This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].
Disorder

MIM: 176797

Leukemia, acute promyelocytic, PL2F/RARA type (3); Skeletal defects,

mRNA Protein Product Sequence Price Select
NM_001018011, 66932931 NP_001018011, 66932932 zinc finger and BTB domain-containing protein 16 Full Length $655.98
ORF Sequence $586.38
NM_006006, 66932930 NP_005997, 21359888 zinc finger and BTB domain-containing protein 16 Full Length $700.93
ORF Sequence $586.38
KEGG
hsa05202Transcriptional misregulation in cancer
hsa05200Pathways in cancer
hsa05221Acute myeloid leukemia
Reactome
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_6900Immune System
REACT_75774Adaptive Immune System
REACT_75842Antigen processing: Ubiquitination & Proteasome degradation
Homo sapiens (human)ZBTB16NP_001018011.1
Pan troglodytes (chimpanzee)ZBTB16XP_003313422.1
Macaca mulatta (Rhesus monkey)ZBTB16XP_001086244.1
Canis lupus familiaris (dog)ZBTB16XP_850343.1
Bos taurus (cattle)ZBTB16NP_001032553.1
Mus musculus (house mouse)Zbtb16NP_001028496.1
Rattus norvegicus (Norway rat)Zbtb16NP_001013199.1
Gallus gallus (chicken)ZBTB16XP_417898.3
Danio rerio (zebrafish)zbtb16aNP_955929.1
GeneCards ZBTB16
PDB 1CS3, 1BUO
UniProt Q05516
MIM 176797
Ensembl ENSG00000109906
HGNC 12930
HPRD 11762

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 16
Names
zinc finger and BTB domain-containing protein 16
zinc finger protein PLZF
zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)

Interactant

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