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ZMYM2 zinc finger, MYM-type 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001190964 Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001190965 Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_003453 Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_197968 Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005266517 PREDICTED: Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005266518 PREDICTED: Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005266519 PREDICTED: Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005266520 PREDICTED: Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005266521 PREDICTED: Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant X6, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006719864 PREDICTED: Homo sapiens zinc finger, MYM-type 2 (ZMYM2), transcript variant X7, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol ZMYM2
Entrez Gene ID 7750
Full Name zinc finger, MYM-type 2
Synonyms FIM, MYM, RAMP, SCLL, ZNF198
General protein information
Preferred Names
zinc finger MYM-type protein 2
Names
zinc finger MYM-type protein 2
zinc finger protein 198
fused in myeloproliferative disorders protein
rearranged in an atypical myeloproliferative disorder
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q11-q12

Summary The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010].
Disorder

MIM: 602221

mRNA Protein Product Sequence Price Select
NM_001190964, 597955376 NP_001177893, 300192959 zinc finger MYM-type protein 2 ORF Sequence $1500.00
NM_001190965, 597955377 NP_001177894, 300192961 zinc finger MYM-type protein 2 ORF Sequence $1500.00
NM_003453, 597955374 NP_003444, 4508011 zinc finger MYM-type protein 2 ORF Sequence $1500.00
NM_197968, 597955375 NP_932072, 37574606 zinc finger MYM-type protein 2 ORF Sequence $1500.00
XM_005266517, 530402628 XP_005266574, 530402629 zinc finger MYM-type protein 2 isoform X2 ORF Sequence $1500.00
XM_005266518, 530402630 XP_005266575, 530402631 zinc finger MYM-type protein 2 isoform X3 ORF Sequence $1500.00
XM_005266519, 530402632 XP_005266576, 530402633 zinc finger MYM-type protein 2 isoform X4 ORF Sequence $1500.00
XM_005266520, 530402634 XP_005266577, 530402635 zinc finger MYM-type protein 2 isoform X5 ORF Sequence $1500.00
XM_005266521, 530402636 XP_005266578, 530402637 zinc finger MYM-type protein 2 isoform X6 ORF Sequence $1500.00
XM_006719864, 578824998 XP_006719927, 578824999 zinc finger MYM-type protein 2 isoform X7 ORF Sequence $1500.00
Reactome
REACT_116125Disease
REACT_121141Signaling by FGFR1 fusion mutants
REACT_120736Signaling by FGFR in disease
REACT_121398Signaling by FGFR mutants
REACT_120999Signaling by FGFR1 mutants
Homo sapiens (human)ZMYM2NP_932072.1
Pan troglodytes (chimpanzee)ZMYM2XP_003314108.1
Macaca mulatta (Rhesus monkey)ZMYM2XP_002800725.1
Canis lupus familiaris (dog)ZMYM2XP_005635627.1
Mus musculus (house mouse)Zmym2NP_083774.2
Rattus norvegicus (Norway rat)Zmym2XP_006252149.1
Gallus gallus (chicken)ZMYM2XP_004938870.1
Danio rerio (zebrafish)zmym2XP_001923572.4
Process
IDNameEvidence
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedIEA
GO:0008150biological_processND
Component
IDNameEvidence
GO:0005829cytosolTAS
GO:0016605PML bodyIDA
Function
IDNameEvidence
GO:0008270zinc ion bindingNAS
GO:0031624ubiquitin conjugating enzyme bindingIPI
GeneCards ZMYM2
UniProt A8K126, Q9UBW7
Vega OTTHUMG00000016507
MIM 602221
Ensembl ENSG00000121741
HGNC 12989
HPRD 03745

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the ZMYM2 gene?

The ZMYM2 gene (previously known as ZNF198) provides instructions for making a protein whose function is not clearly understood. It is a member of a family of zinc finger proteins, which contain one or more short regions called zinc finger domains. The zinc finger domains in the ZMYM2 protein are thought to allow it to regulate interactions between other proteins. ZMYM2 is found in the nucleus of the cell, where it likely associates with other proteins. Through these associations, the ZMYM2 protein may be involved in repairing DNA mistakes, controlling gene activity, or forming structures in the nucleus called PML nuclear bodies that block the growth and division of cells and promote their self-destruction (apoptosis).

Interactant

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