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Sequence in raw or FASTA format:

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RAB7A RAB7A, member RAS oncogene family [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_004637 Homo sapiens RAB7A, member RAS oncogene family (RAB7A), mRNA. ORF Sequence $180.96
Peptide Services
Antibody Services
Protein Services


Gene Symbol RAB7A
Entrez Gene ID 7879
Full Name RAB7A, member RAS oncogene family
Synonyms FLJ20819, PRO2706, RAB7
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3q21.3

Summary RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602298

Charcot-Marie-Tooth disease, type 2B, 600882 (3)

mRNA Protein Product Sequence Price Select
NM_004637, 40807361 NP_004628, 34147513 ras-related protein Rab-7a Full Length $649.60
ORF Sequence $180.96
KEGG
hsa05132Salmonella infection
hsa04145Phagosome
hsa04144Endocytosis
hsa05152Tuberculosis
hsa05146Amoebiasis
Pathway Interaction Database
il12_2pathwayIL12-mediated signaling events
Reactome
REACT_121399MHC class II antigen presentation
REACT_75774Adaptive Immune System
REACT_6900Immune System
Homo sapiens (human)RAB7ANP_004628.4
Pan troglodytes (chimpanzee)RAB7AXP_526302.3
Macaca mulatta (Rhesus monkey)RAB7AXP_001095709.2
Canis lupus familiaris (dog)RAB7ANP_001003316.1
Bos taurus (cattle)RAB7ANP_001030253.1
Mus musculus (house mouse)Rab7NP_033031.2
Rattus norvegicus (Norway rat)Rab7aNP_076440.1
Gallus gallus (chicken)RAB7AXP_414359.1
Danio rerio (zebrafish)rab7NP_957222.1
Drosophila melanogaster (fruit fly)Rab7NP_524472.1
Caenorhabditis elegansrab-7NP_496549.1
Arabidopsis thaliana (thale cress)RABG3ENP_001031161.1
Arabidopsis thaliana (thale cress)RAB7BNP_188512.1
GeneCards RAB7A
PDB 1YHN, 1T91, 3LAW
UniProt P51149
MIM 602298
Ensembl ENSG00000075785
HGNC 9788
HPRD 03805

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ras-related protein Rab-7a
Names
ras-related protein Rab-7a
Ras-associated protein RAB7
RAB7, member RAS oncogene family

Interactant

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