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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


MLPH melanophilin [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu00565 NM_001042467 Homo sapiens melanophilin (MLPH), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu00622 NM_024101 Homo sapiens melanophilin (MLPH), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu07874 NM_001281474 Homo sapiens melanophilin (MLPH), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu10316 NM_001281473 Homo sapiens melanophilin (MLPH), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu36597 XM_006712737 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu36598 XM_006712738 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu36599 XM_006712739 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu36600 XM_006712740 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu36601 XM_006712741 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu36602 XM_006712742 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu00565C NM_001042467 Homo sapiens melanophilin (MLPH), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu00622C NM_024101 Homo sapiens melanophilin (MLPH), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OHu07874C NM_001281474 Homo sapiens melanophilin (MLPH), transcript variant 4, mRNA. Customized vector On-demand 7-9 $269.00
OHu10316C NM_001281473 Homo sapiens melanophilin (MLPH), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00
OHu36597C XM_006712737 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00
OHu36598C XM_006712738 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OHu36599C XM_006712739 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00
OHu36600C XM_006712740 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X4, mRNA. Customized vector On-demand 7-9 $269.00
OHu36601C XM_006712741 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X5, mRNA. Customized vector On-demand 7-9 $269.00
OHu36602C XM_006712742 PREDICTED: Homo sapiens melanophilin (MLPH), transcript variant X6, mRNA. Customized vector On-demand 7-9 $269.00

*Business Day

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Gene Symbol MLPH
Entrez Gene ID 79083
Full Name melanophilin
Synonyms SLAC2-A
General protein information
Preferred Names
melanophilin
Names
melanophilin
exophilin-3
synaptotagmin-like protein 2a
slp homolog lacking C2 domains a
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q37.3

Summary This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013].
Disorder

MIM: 606526

Griscelli syndrome, type 3, 609227 (3)

mRNA Protein Product Sequence Price Select
NM_001042467, 527317392 NP_001035932, 109826351 melanophilin isoform 2 ORF Sequence $700.00
NM_001281473, 527317393 NP_001268402, 527317394 melanophilin isoform 3 ORF Sequence $550.00
NM_001281474, 527317395 NP_001268403, 527317396 melanophilin isoform 4 ORF Sequence $550.00
NM_024101, 527317391 NP_077006, 13129108 melanophilin isoform 1 ORF Sequence $700.00
XM_006712737, 578804868 XP_006712800, 578804869 melanophilin isoform X1 ORF Sequence $550.00
XM_006712738, 578804870 XP_006712801, 578804871 melanophilin isoform X2 ORF Sequence $550.00
XM_006712739, 578804872 XP_006712802, 578804873 melanophilin isoform X3 ORF Sequence $550.00
XM_006712740, 578804874 XP_006712803, 578804875 melanophilin isoform X4 ORF Sequence $550.00
XM_006712741, 578804876 XP_006712804, 578804877 melanophilin isoform X5 ORF Sequence $550.00
XM_006712742, 578804878 XP_006712805, 578804879 melanophilin isoform X6 ORF Sequence $550.00
WikiPathways
WP2291Deregulation of Rab and Rab Effector Genes in Bladder Cancer
Homo sapiens (human)MLPHNP_077006.1
Pan troglodytes (chimpanzee)MLPHXP_516180.3
Canis lupus familiaris (dog)MLPHNP_001096689.2
Bos taurus (cattle)MLPHNP_001075066.1
Mus musculus (house mouse)MlphNP_443748.2
Rattus norvegicus (Norway rat)MlphNP_001012135.1
Danio rerio (zebrafish)LOC557015XP_005167685.1
Process
IDNameEvidence
GO:0006605protein targetingIEA
GO:0030318melanocyte differentiationIEA
GO:0032400melanosome localizationIEA
Component
IDNameEvidence
GO:0001725stress fiberIEA
GO:0005815microtubule organizing centerIEA
GO:0030864cortical actin cytoskeletonIEA
GO:0035371microtubule plus-endIEA
Function
IDNameEvidence
GO:0003779actin bindingIEA
GO:0017137Rab GTPase bindingIEA
GO:0031489myosin V bindingIEA
GO:0046872metal ion bindingIEA
GO:0051010microtubule plus-end bindingIEA
GeneCards MLPH
UniProt B3KSS2, Q9BV36, G5E9G5
Vega OTTHUMG00000133298
MIM 606526
Ensembl ENSG00000115648
HGNC 29643
HPRD 09409

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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