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CARD14 caspase recruitment domain family, member 14 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu10658 NM_052819 Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20651 NM_024110 Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu31526 NM_001257970 Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu10658C NM_052819 Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu20651C NM_024110 Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 1, mRNA. Customized vector On-demand 25 $1699.00
OHu31526C NM_001257970 Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 3, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol CARD14
Entrez Gene ID 79092
Full Name caspase recruitment domain family, member 14
Synonyms BIMP2, CARMA2, PRP, PSORS2, PSS1
General protein information
Preferred Names
caspase recruitment domain-containing protein 14
Names
caspase recruitment domain-containing protein 14
carma 2
card-maguk protein 2
CARD-containing MAGUK protein 2
bcl10-interacting maguk protein 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q25

Summary This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012].
Disorder

MIM: 607211

mRNA Protein Product Sequence Price Select
NM_001257970, 384229039 NP_001244899, 384229040 caspase recruitment domain-containing protein 14 isoform 3 ORF Sequence $700.00
NM_024110, 384229056 NP_077015, 332801087 caspase recruitment domain-containing protein 14 isoform 1 ORF Sequence $1500.00
NM_052819, 332801088 NP_438170, 16507955 caspase recruitment domain-containing protein 14 isoform 2 ORF Sequence $550.00
Homo sapiens (human)CARD14NP_077015.2
Pan troglodytes (chimpanzee)CARD14XP_511725.3
Macaca mulatta (Rhesus monkey)CARD14XP_001110299.1
Canis lupus familiaris (dog)CARD14XP_540472.3
Bos taurus (cattle)CARD14NP_001192830.1
Mus musculus (house mouse)Card14NP_570956.1
Rattus norvegicus (Norway rat)Card14XP_006248022.1
Danio rerio (zebrafish)card14XP_697127.4
Xenopus (Silurana) tropicalis (western clawed frog)card14XP_002937355.2
Process
IDNameEvidence
GO:0001934positive regulation of protein phosphorylationIDA
GO:0006915apoptotic processIEA
GO:0007250activation of NF-kappaB-inducing kinase activityNAS
GO:0033209tumor necrosis factor-mediated signaling pathwayIMP
GO:0043066negative regulation of apoptotic processIMP
GO:0051092positive regulation of NF-kappaB transcription factor activityIMP
Component
IDNameEvidence
GO:0005737cytoplasmIDA
GO:0005886plasma membraneNAS
Function
IDNameEvidence
GO:0050700CARD domain bindingIPI
GeneCards CARD14
UniProt Q9BXL6
Vega OTTHUMG00000177549
MIM 607211
Ensembl ENSG00000141527
HGNC 16446
HPRD 06235

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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