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DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu26667 NM_025219 Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu26667C NM_025219 Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol DNAJC5
Entrez Gene ID 80331
Full Name DnaJ (Hsp40) homolog, subfamily C, member 5
Synonyms CLN4, CLN4B, CSP, DNAJC5A, NCL
General protein information
Preferred Names
dnaJ homolog subfamily C member 5
Names
dnaJ homolog subfamily C member 5
cysteine string protein alpha
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20q13.33

Summary This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010].
Disorder

MIM: 611203

mRNA Protein Product Sequence Price Select
NM_025219, 313103004 NP_079495, 45504382 dnaJ homolog subfamily C member 5 ORF Sequence $250.00
KEGG
hsa04141Protein processing in endoplasmic reticulum
Reactome
REACT_13723Neurotransmitter Release Cycle
REACT_13477Transmission across Chemical Synapses
REACT_13685Neuronal System
REACT_23947GABA synthesis, release, reuptake and degradation
Homo sapiens (human)DNAJC5NP_079495.1
Pan troglodytes (chimpanzee)DNAJC5XP_530321.2
Macaca mulatta (Rhesus monkey)DNAJC5XP_001084014.1
Canis lupus familiaris (dog)DNAJC5XP_005635371.1
Bos taurus (cattle)DNAJC5NP_776958.2
Mus musculus (house mouse)Dnajc5NP_058055.1
Rattus norvegicus (Norway rat)Dnajc5NP_077075.1
Gallus gallus (chicken)DNAJC5NP_001264937.1
Danio rerio (zebrafish)dnajc5aaNP_001002464.1
Danio rerio (zebrafish)dnajc5abXP_001338363.1
Drosophila melanogaster (fruit fly)CspNP_524213.1
Process
IDNameEvidence
GO:0007268synaptic transmissionTAS
GO:0007269neurotransmitter secretionTAS
GO:0008219cell deathIEA
GO:0043524negative regulation of neuron apoptotic processIEA
Component
IDNameEvidence
GO:0005739mitochondrionIDA
GO:0005765lysosomal membraneIDA
GO:0005886plasma membraneIDA
GO:0005886plasma membraneTAS
GO:0008021synaptic vesicleIEA
GO:0016020membraneIDA
GO:0042470melanosomeIEA
GO:0061202clathrin-sculpted gamma-aminobutyric acid transport vesicle membraneTAS
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0001948glycoprotein bindingIEA
GO:0043008ATP-dependent protein bindingIEA
GeneCards DNAJC5
UniProt Q6AHX3, Q9H3Z4
Vega OTTHUMG00000033007
MIM 611203
Ensembl ENSG00000101152
HGNC 16235
HPRD 08539

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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