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CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu21723 NM_003476 Homo sapiens cysteine and glycine-rich protein 3 (cardiac LIM protein) (CSRP3), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu45019 XM_006718339 PREDICTED: Homo sapiens cysteine and glycine-rich protein 3 (cardiac LIM protein) (CSRP3), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu21723C NM_003476 Homo sapiens cysteine and glycine-rich protein 3 (cardiac LIM protein) (CSRP3), mRNA. Customized vector In-stock 5-7 $149.00
OHu45019C XM_006718339 PREDICTED: Homo sapiens cysteine and glycine-rich protein 3 (cardiac LIM protein) (CSRP3), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol CSRP3
Entrez Gene ID 8048
Full Name cysteine and glycine-rich protein 3 (cardiac LIM protein)
Synonyms CLP, CMD1M, CMH12, CRP3, LMO4, MLP
General protein information
Preferred Names
cysteine and glycine-rich protein 3
Names
cysteine and glycine-rich protein 3
LIM domain only 4
muscle LIM protein
cardiac LIM domain protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.1

Summary This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600824

Cardiomyopathy, dilated, 1M, 607482 (3); Cardiomyopathy,

mRNA Protein Product Sequence Price Select
NM_003476, 390608663 NP_003467, 4502893 cysteine and glycine-rich protein 3 ORF Sequence $159.00
XM_006718339, 578820840 XP_006718402, 578820841 cysteine and glycine-rich protein 3 isoform X1 ORF Sequence $250.00
Homo sapiens (human)CSRP3NP_003467.1
Pan troglodytes (chimpanzee)CSRP3XP_528813.2
Macaca mulatta (Rhesus monkey)CSRP3XP_001095430.1
Canis lupus familiaris (dog)CSRP3XP_852328.1
Bos taurus (cattle)CSRP3NP_001019860.1
Mus musculus (house mouse)Csrp3NP_001185770.1
Rattus norvegicus (Norway rat)Csrp3NP_476485.1
Gallus gallus (chicken)CSRP3NP_001186415.1
Danio rerio (zebrafish)csrp3NP_001006026.1
Drosophila melanogaster (fruit fly)Mlp60ANP_001137750.1
Xenopus (Silurana) tropicalis (western clawed frog)csrp3NP_001006836.1
Process
IDNameEvidence
GO:0002026regulation of the force of heart contractionISS
GO:0003300cardiac muscle hypertrophyIMP
GO:0006874cellular calcium ion homeostasisISS
GO:0007519skeletal muscle tissue developmentTAS
GO:0033365protein localization to organelleIMP
GO:0035995detection of muscle stretchIMP
GO:0048738cardiac muscle tissue developmentISS
GO:0055003cardiac myofibril assemblyISS
GO:0060048cardiac muscle contractionIMP
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005856cytoskeletonIEA
GO:0030018Z discIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0008307structural constituent of muscleIMP
GO:0031433telethonin bindingIDA
GO:0031433telethonin bindingIPI
GO:0042805actinin bindingISS
GeneCards CSRP3
PDB 2O13, 2O10
UniProt P50461, A2TDB8
Vega OTTHUMG00000166100
MIM 600824
Ensembl ENSG00000129170
HGNC 2472
HPRD 07525

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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