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CAMK2A calcium/calmodulin-dependent protein kinase II alpha [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_015981 Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_171825 Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol CAMK2A
Entrez Gene ID 815
Full Name calcium/calmodulin-dependent protein kinase II alpha
Synonyms CAMKA, KIAA0968
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008].

MIM: 114078

mRNA Protein Product Sequence Price Select
NM_015981, 212549564 NP_057065, 25952114 calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1 ORF Sequence $360.00
NM_171825, 212549565 NP_741960, 25952118 calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2 ORF Sequence $550.00
hsa04012ErbB signaling pathway
hsa04114Oocyte meiosis
hsa04912GnRH signaling pathway
hsa04740Olfactory transduction
hsa04725Cholinergic synapse
hsa04728Dopaminergic synapse
hsa05031Amphetamine addiction
hsa04971Gastric acid secretion
hsa04066HIF-1 signaling pathway
hsa04020Calcium signaling pathway
hsa04713Circadian entrainment
hsa04720Long-term potentiation
hsa04310Wnt signaling pathway
hsa04722Neurotrophin signaling pathway
Pathway Interaction Database
ifngpathwayIFN-gamma pathway
fgf_pathwayFGF signaling pathway
tgfbrpathwayTGF-beta receptor signaling
pi3kplctrkpathwayTrk receptor signaling mediated by PI3K and PLC-gamma
wnt_noncanonical_pathwayNoncanonical Wnt signaling pathway
WP2256Integrated Pancreatic Cancer Pathway
WP366TGF-beta Receptor Signaling Pathway
WP437EGFR1 Signaling Pathway
WP2377Integrated Pancreatic Cancer Pathway
WP289Myometrial Relaxation and Contraction Pathways
WP536Calcium Regulation in the Cardiac Cell
WP363Wnt Signaling Pathway NetPath
WP673ErbB signaling pathway
REACT_6900Immune System
REACT_20546Ras activation uopn Ca2+ infux through NMDA receptor
REACT_18307Trafficking of AMPA receptors
REACT_20593Post NMDA receptor activation events
REACT_20568CREB phosphorylation through the activation of Ras
REACT_13685Neuronal System
REACT_18347Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
REACT_20642CREB phosphorylation through the activation of CaMKII
REACT_25229Interferon Signaling
REACT_20563Activation of NMDA receptor upon glutamate binding and postsynaptic events
REACT_20594Unblocking of NMDA receptor, glutamate binding and activation
REACT_75790Cytokine Signaling in Immune system
REACT_13477Transmission across Chemical Synapses
REACT_25078Interferon gamma signaling
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Homo sapiens (human)CAMK2ANP_057065.2
Pan troglodytes (chimpanzee)CAMK2AXP_001165329.2
Canis lupus familiaris (dog)CAMK2AXP_853581.1
Bos taurus (cattle)CAMK2ANP_001069406.1
Mus musculus (house mouse)Camk2aNP_803126.1
Rattus norvegicus (Norway rat)Camk2aNP_037052.1
Gallus gallus (chicken)CAMK2ANP_989626.1
Danio rerio (zebrafish)camk2aNP_001017741.2
Arabidopsis thaliana (thale cress)CPK29NP_974150.2
GeneCards CAMK2A
UniProt Q7LDD5, Q9UQM7, Q8IWE0, A8K161
MIM 114078
Ensembl ENSG00000070808
HGNC 1460
HPRD 06532

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
calcium/calmodulin-dependent protein kinase type II subunit alpha
calcium/calmodulin-dependent protein kinase type II subunit alpha
CaMK-II alpha subunit
caMK-II subunit alpha
CaM-kinase II alpha chain
CaM kinase II alpha subunit
caM kinase II subunit alpha
calcium/calmodulin-dependent protein kinase II alpha-B subunit
calcium/calmodulin-dependent protein kinase type II alpha chain
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha


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