• THAT   AND

Sequence in raw or FASTA format:


Blast Method:


CASR calcium-sensing receptor [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000388 Homo sapiens calcium-sensing receptor (CASR), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001178065 Homo sapiens calcium-sensing receptor (CASR), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol CASR
Entrez Gene ID 846
Full Name calcium-sensing receptor
Synonyms CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, MGC138441, NSHPT, PCAR1
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008].

MIM: 601199

Hypocalciuric hypercalcemia, type I, 145980 (3); Hyperparathyroidism,

mRNA Protein Product Sequence Price Select
NM_000388, 189409146 NP_000379, 37577159 extracellular calcium-sensing receptor isoform 2 precursor ORF Sequence $1500.00
NM_001178065, 296010810 NP_001171536, 296010811 extracellular calcium-sensing receptor isoform 1 precursor ORF Sequence $1500.00
WP501GPCRs, Class C Metabotropic glutamate, pheromone
Pathway Interaction Database
ecadherin_keratinocyte_pathwayE-cadherin signaling in keratinocytes
REACT_111102Signal Transduction
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_18319Class C/3 (Metabotropic glutamate/pheromone receptors)
REACT_21340GPCR ligand binding
REACT_14797Signaling by GPCR
Homo sapiens (human)CASRNP_001171536.1
Pan troglodytes (chimpanzee)CASRXP_516689.2
Macaca mulatta (Rhesus monkey)CASRXP_001112009.2
Canis lupus familiaris (dog)CASRNP_001074978.1
Bos taurus (cattle)CASRNP_776427.1
Mus musculus (house mouse)CasrNP_038831.2
Rattus norvegicus (Norway rat)CasrNP_058692.1
Gallus gallus (chicken)CASRXP_416491.3
Danio rerio (zebrafish)LOC560607XP_689097.1
GeneCards CASR
UniProt P41180
MIM 601199
Ensembl ENSG00000036828
HGNC 1514
HPRD 03122

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
extracellular calcium-sensing receptor
extracellular calcium-sensing receptor
parathyroid Ca(2+)-sensing receptor 1
parathyroid cell calcium-sensing receptor


Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.