• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


CAT catalase [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001752 Homo sapiens catalase (CAT), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

*Business Day

Related Services

Gene Symbol CAT
Entrez Gene ID 847
Full Name catalase
Synonyms MGC138422, MGC138424
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p13

Summary This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009].
Disorder

MIM: 115500

Acatalasemia (3)

mRNA Protein Product Sequence Price Select
NM_001752, 260436906 NP_001743, 4557014 catalase ORF Sequence $360.00
KEGG
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa00380Tryptophan metabolism
hsa04146Peroxisome
hsa00630Glyoxylate and dicarboxylate metabolism
Pathway Interaction Database
foxopathwayFoxO family signaling
WikiPathways
WP15Selenium Pathway
WP465Tryptophan metabolism
WP408Oxidative Stress
WP176Folate Metabolism
WP710DNA damage response (only ATM dependent)
BIOCYC
HUMAN_DETOX1-PWYsuperoxide radicals degradation
HUMAN_PWY66-162ethanol degradation IV
META_PWY66-162ethanol degradation IV
Reactome
REACT_1698Metabolism of nucleotides
REACT_522Purine metabolism
REACT_111217Metabolism
REACT_2086Purine catabolism
Homo sapiens (human)CATNP_001743.1
Pan troglodytes (chimpanzee)CATXP_001147928.1
Macaca mulatta (Rhesus monkey)CATXP_001115625.1
Canis lupus familiaris (dog)CATNP_001002984.1
Bos taurus (cattle)CATNP_001030463.1
Mus musculus (house mouse)CatNP_033934.2
Rattus norvegicus (Norway rat)CatNP_036652.1
Gallus gallus (chicken)CATNP_001026386.1
Danio rerio (zebrafish)catNP_570987.1
Drosophila melanogaster (fruit fly)CatNP_536731.1
Drosophila melanogaster (fruit fly)CG9314NP_609248.1
Caenorhabditis elegansctl-1NP_496979.2
Caenorhabditis elegansctl-2NP_001022473.1
Caenorhabditis elegansctl-3NP_741058.1
Arabidopsis thaliana (thale cress)CAT2NP_195235.1
Arabidopsis thaliana (thale cress)CAT1NP_564121.1
GeneCards CAT
PDB 1DGG, 1F4J, 1DGF, 1QQW, 1DGB, 1DGH
UniProt P04040
MIM 115500
Ensembl ENSG00000121691
HGNC 1516
HPRD 00282

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
catalase
Names
catalase
NP_001743.1

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.