• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


TCAP titin-cap (telethonin) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_003673 Homo sapiens titin-cap (TCAP), mRNA. ORF Sequence $159.00
Peptide Services
Antibody Services
Protein Services


Gene Symbol TCAP
Entrez Gene ID 8557
Full Name titin-cap (telethonin)
Synonyms CMD1N, LGMD2G, T-cap, TELE, telethonin
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q12

Summary Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604488

Muscular dystrophy, limb-girdle, type 2G, 601954 (3);

mRNA Protein Product Sequence Price Select
NM_003673, 209862803 NP_003664, 4507435 telethonin Full Length $279.27
ORF Sequence $159.00
WikiPathways
WP383Striated Muscle Contraction
Reactome
REACT_17044Muscle contraction
REACT_16969Striated Muscle Contraction
Homo sapiens (human)TCAPNP_003664.1
Pan troglodytes (chimpanzee)TCAPXP_511458.3
Macaca mulatta (Rhesus monkey)TCAPXP_001089621.1
Canis lupus familiaris (dog)TCAPNP_001128597.1
Bos taurus (cattle)TCAPNP_001014915.1
Mus musculus (house mouse)TcapNP_035670.2
Danio rerio (zebrafish)tcapXP_684103.1
GeneCards TCAP
PDB 2F8V, 1YA5
UniProt O15273, A2TDC0
MIM 604488
Ensembl ENSG00000173991
HGNC 11610
HPRD 05133

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
telethonin
Names
telethonin
titin cap protein
19 kDa sarcomeric protein
limb girdle muscular dystrophy 2G (autosomal recessive)

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Secured Online Quotation
Email: gene@genscript.com
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262 1-732-885-5878