• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001126054 Homo sapiens calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 2, mRNA. ORF Sequence $782.13
Peptide Services
Antibody Services
Protein Services
NM_001126055 Homo sapiens calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 3, mRNA. ORF Sequence $781.26
Peptide Services
Antibody Services
Protein Services
NM_003688 Homo sapiens calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1, mRNA. ORF Sequence $802.14
Peptide Services
Antibody Services
Protein Services


Gene Symbol CASK
Entrez Gene ID 8573
Full Name calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Synonyms CAGH39, CAMGUK, CMG, FGS4, FLJ22219, FLJ31914, LIN2, MICPCH, TNRC8
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp11.4

Summary This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
Disorder

MIM: 300172

Mental retardation and microcephaly with pontine and cerebellar

mRNA Protein Product Sequence Price Select
NM_001126054, 193788695 NP_001119526, 186700627 peripheral plasma membrane protein CASK isoform 2 Full Length $0.00
ORF Sequence $782.13
NM_001126055, 193794869 NP_001119527, 186700629 peripheral plasma membrane protein CASK isoform 3 Full Length $0.00
ORF Sequence $781.26
NM_003688, 193788694 NP_003679, 186972120 peripheral plasma membrane protein CASK isoform 1 Full Length $0.00
ORF Sequence $802.14
KEGG
hsa04530Tight junction
WikiPathways
WP2359Parkin-Ubiquitin Proteasomal System pathway
Pathway Interaction Database
syndecan_3_pathwaySyndecan-3-mediated signaling events
syndecan_2_pathwaySyndecan-2-mediated signaling events
syndecan_1_pathwaySyndecan-1-mediated signaling events
Reactome
REACT_23832Nephrin interactions
REACT_111155Cell-Cell communication
Homo sapiens (human)CASKNP_003679.2
Pan troglodytes (chimpanzee)CASKXP_003317477.2
Macaca mulatta (Rhesus monkey)CASKXP_001095837.2
Canis lupus familiaris (dog)CASKXP_850618.2
Bos taurus (cattle)CASKNP_001095951.1
Mus musculus (house mouse)CaskNP_033936.2
Rattus norvegicus (Norway rat)CaskNP_071520.1
Gallus gallus (chicken)CASKXP_416769.2
Danio rerio (zebrafish)caskbNP_001135848.1
Drosophila melanogaster (fruit fly)CASKNP_001163681.1
Caenorhabditis eleganslin-2NP_001024587.1
GeneCards CASK
PDB 3TAC, 3C0I, 3C0G, 3MFU, 1KGD, 3C0H, 1KWA, 1ZL8, 3MFT, 3MFR, 3MFS
UniProt O14936
MIM 300172
Ensembl ENSG00000147044
HGNC 1497
HPRD 02164

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
peripheral plasma membrane protein CASK
Names
peripheral plasma membrane protein CASK
hCASK
protein lin-2 homolog
trinucleotide repeat containing 8
calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase
NP_001119526.1
NP_001119527.1
NP_003679.2

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Secured Online Quotation
Email: gene@genscript.com
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262 1-732-885-5878