TRIM4 tripartite motif containing 4 [Homo sapiens (human)]
| Gene Symbol | TRIM4 |
| Entrez Gene ID | 89122 |
| Full Name | tripartite motif containing 4 |
| Synonyms | RNF87 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
7 7q22-q31.1 |
| Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq]. |
| Disorder | MIM: |
| mRNA | NM_033017, 301601614 |
| Protein | NP_148977, 301601615 |
| Product | tripartite motif-containing protein 4 isoform alpha |
| RefSeq Status | REVIEWED |
| mRNA | NM_033091, 301601616 |
| Protein | NP_149082, 15011941 |
| Product | tripartite motif-containing protein 4 isoform beta |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | TRIM4 | NP_149082.1 |
| Pan troglodytes (chimpanzee) | TRIM4 | XP_519244.2 |
| Canis lupus familiaris (dog) | TRIM4 | XP_850838.1 |
| Bos taurus (cattle) | TRIM4 | XP_605970.3 |
| ID | Name | Evidence |
| GO:0070206 | protein trimerization | IDA |
Component
| ID | Name | Evidence |
| GO:0005622 | intracellular | IEA |
| GO:0005737 | cytoplasm | IDA |
| GO:0005886 | plasma membrane | IDA |
Function
| ID | Name | Evidence |
| GO:0008270 | zinc ion binding | IEA |
| GO:0046872 | metal ion binding | IEA |
| GeneCards | TRIM4 |
| UniProt | Q9C037 |
| Ensembl | ENSG00000146833 |
| HGNC | 16275 |
| HPRD | 15556 |
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