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AIP aryl hydrocarbon receptor interacting protein [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18826 NM_003977 Homo sapiens aryl hydrocarbon receptor interacting protein (AIP), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu18826C NM_003977 Homo sapiens aryl hydrocarbon receptor interacting protein (AIP), mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol AIP
Entrez Gene ID 9049
Full Name aryl hydrocarbon receptor interacting protein
Synonyms ARA9, FKBP16, FKBP37, SMTPHN, XAP-2, XAP2
General protein information
Preferred Names
AH receptor-interacting protein
Names
AH receptor-interacting protein
immunophilin homolog ARA9
HBV X-associated protein 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q13.3

Summary The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. [provided by RefSeq, Sep 2008].
Disorder

MIM: 605555

Pituitary adenoma, growth hormone-secreting, 102200 (3);

mRNA Protein Product Sequence Price Select
NM_003977, 201860299 NP_003968, 201860300 AH receptor-interacting protein ORF Sequence $400.00
WikiPathways
WP2100AhR pathway
Homo sapiens (human)AIPNP_003968.2
Pan troglodytes (chimpanzee)AIPXP_508597.1
Macaca mulatta (Rhesus monkey)AIPXP_001105624.1
Canis lupus familiaris (dog)AIPXP_851841.1
Bos taurus (cattle)AIPNP_898905.1
Mus musculus (house mouse)AipNP_057875.1
Rattus norvegicus (Norway rat)AipNP_758830.2
Gallus gallus (chicken)AIPNP_989800.1
Danio rerio (zebrafish)aipNP_999877.1
Danio rerio (zebrafish)LOC100149392XP_001922877.1
Drosophila melanogaster (fruit fly)CG1847NP_727574.2
Caenorhabditis elegansC56C10.10NP_495339.1
Xenopus (Silurana) tropicalis (western clawed frog)aipNP_001096219.1
Process
IDNameEvidence
GO:0006626protein targeting to mitochondrionIDA
GO:0006805xenobiotic metabolic processIEA
GO:0007165signal transductionTAS
GO:0010738regulation of protein kinase A signalingIEA
GO:0022417protein maturation by protein foldingIDA
GO:0051344negative regulation of cyclic-nucleotide phosphodiesterase activityIEA
GO:2001141regulation of RNA biosynthetic processIEA
GO:2001141regulation of RNA biosynthetic processTAS
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolIDA
GO:0005829cytosolTAS
GO:0005886plasma membraneIDA
Function
IDNameEvidence
GO:0003713transcription coactivator activityTAS
GO:0004871signal transducer activityTAS
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingTAS
GO:0036004GAF domain bindingIDA
GO:0051082unfolded protein bindingIDA
GeneCards AIP
PDB 2LKN, 4AIF, 4APO
UniProt O00170
Vega OTTHUMG00000167674
MIM 605555
Ensembl ENSG00000110711
HGNC 358
HPRD 10408

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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