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Sequence in raw or FASTA format:

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CRLF1 cytokine receptor-like factor 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18874 NM_004750 Homo sapiens cytokine receptor-like factor 1 (CRLF1), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu51895 XM_006722934 PREDICTED: Homo sapiens cytokine receptor-like factor 1 (CRLF1), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu18874C NM_004750 Homo sapiens cytokine receptor-like factor 1 (CRLF1), mRNA. Customized vector On-demand 7-9 $269.00
OHu51895C XM_006722934 PREDICTED: Homo sapiens cytokine receptor-like factor 1 (CRLF1), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol CRLF1
Entrez Gene ID 9244
Full Name cytokine receptor-like factor 1
Synonyms CISS, CISS1, CLF, CLF-1, NR6, zcytor5
General protein information
Preferred Names
cytokine receptor-like factor 1
Names
cytokine receptor-like factor 1
cytokine-like factor 1
class I cytokine receptor
cytokine type 1 receptor CRLP-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p12

Summary This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009].
Disorder

MIM: 604237

Cold-induced sweating syndrome, 272430 (3); Crisponi syndrome,

mRNA Protein Product Sequence Price Select
NM_004750, 260655997 NP_004741, 4758062 cytokine receptor-like factor 1 precursor ORF Sequence $550.00
XM_006722934, 578833718 XP_006722997, 578833719 cytokine receptor-like factor 1 isoform X1 ORF Sequence $400.00
Homo sapiens (human)CRLF1NP_004741.1
Pan troglodytes (chimpanzee)CRLF1XP_001135263.3
Macaca mulatta (Rhesus monkey)CRLF1XP_001115478.2
Canis lupus familiaris (dog)CRLF1XP_005633255.1
Bos taurus (cattle)CRLF1XP_002688582.2
Mus musculus (house mouse)Crlf1NP_061297.1
Rattus norvegicus (Norway rat)Crlf1NP_001099544.1
Gallus gallus (chicken)CRLF1XP_004948964.1
Danio rerio (zebrafish)crlf1aNP_001002650.1
Xenopus (Silurana) tropicalis (western clawed frog)crlf1XP_002940253.2
Process
IDNameEvidence
GO:0001657ureteric bud developmentIEA
GO:0008284positive regulation of cell proliferationIDA
GO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinIDA
GO:0043524negative regulation of neuron apoptotic processIDA
GO:2000672negative regulation of motor neuron apoptotic processIEA
Component
IDNameEvidence
GO:0005615extracellular spaceTAS
GO:0097058CRLF-CLCF1 complexIDA
Function
IDNameEvidence
GO:0004872receptor activityTAS
GO:0005125cytokine activityIDA
GO:0005127ciliary neurotrophic factor receptor bindingIDA
GO:0005515protein bindingIPI
GO:0019955cytokine bindingIPI
GO:0046982protein heterodimerization activityIDA
GeneCards CRLF1
UniProt O75462
Vega OTTHUMG00000183111
MIM 604237
Ensembl ENSG00000006016
HGNC 2364
HPRD 09177

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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