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MMP20 matrix metallopeptidase 20 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_004771 Homo sapiens matrix metallopeptidase 20 (MMP20), mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol MMP20
Entrez Gene ID 9313
Full Name matrix metallopeptidase 20
Synonyms AI2A2, MMP-20
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q22.3

Summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011].
Disorder

MIM: 604629

Amelogenesis imperfecta, type IIA2, 612529 (3)

mRNA Protein Product Sequence Price Select
NM_004771, 45359864 NP_004762, 45359865 matrix metalloproteinase-20 preproprotein ORF Sequence $550.00
WikiPathways
WP129Matrix Metalloproteinases
Homo sapiens (human)MMP20NP_004762.2
Pan troglodytes (chimpanzee)MMP20XP_001153208.1
Macaca mulatta (Rhesus monkey)MMP20XP_001097602.1
Canis lupus familiaris (dog)MMP20XP_854639.1
Bos taurus (cattle)MMP20NP_776816.1
Mus musculus (house mouse)Mmp20NP_038931.1
Rattus norvegicus (Norway rat)Mmp20NP_001100270.1
Danio rerio (zebrafish)LOC100537445XP_003200101.1
GeneCards MMP20
PDB 2JSD
UniProt O60882
MIM 604629
Ensembl ENSG00000137674
HGNC 7167
HPRD 05218

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
matrix metalloproteinase-20
Names
matrix metalloproteinase-20
enamel metalloproteinase
matrix metalloproteinase 20 (enamelysin)
NP_004762.2

Interactant



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