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TNFRSF8 tumor necrosis factor receptor superfamily, member 8 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001243 Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_152942 Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

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Related Services

Gene Symbol TNFRSF8
Entrez Gene ID 943
Full Name tumor necrosis factor receptor superfamily, member 8
Synonyms CD30, D1S166E, Ki-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36

Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Disorder

MIM: 153243

mRNA Protein Product Sequence Price Select
NM_001243, 68348710 NP_001234, 68348711 tumor necrosis factor receptor superfamily member 8 isoform 1 precursor ORF Sequence $700.00
NM_152942, 68348712 NP_694421, 23510437 tumor necrosis factor receptor superfamily member 8 isoform 2 ORF Sequence $99.00
KEGG
hsa04060Cytokine-cytokine receptor interaction
WikiPathways
WP231TNF-alpha/NF-kB Signaling Pathway
Homo sapiens (human)TNFRSF8NP_001234.2
Pan troglodytes (chimpanzee)TNFRSF8XP_514397.3
Macaca mulatta (Rhesus monkey)TNFRSF8XP_001118873.2
Canis lupus familiaris (dog)TNFRSF8XP_544563.4
Bos taurus (cattle)TNFRSF8XP_002694100.1
Mus musculus (house mouse)Tnfrsf8NP_033427.1
Rattus norvegicus (Norway rat)Tnfrsf8NP_062008.1
Gallus gallus (chicken)TNFRSF8NP_989775.1
GeneCards TNFRSF8
PDB 1D01
UniProt P28908
MIM 153243
Ensembl ENSG00000120949
HGNC 11923
HPRD 01074

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
tumor necrosis factor receptor superfamily member 8
Names
tumor necrosis factor receptor superfamily member 8
Ki-1 antigen
CD30L receptor
cytokine receptor CD30
lymphocyte activation antigen CD30

Interactant



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