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CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23151 NM_004273 Homo sapiens carbohydrate (chondroitin 6) sulfotransferase 3 (CHST3), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu23151 XM_006718075 PREDICTED: Homo sapiens carbohydrate (chondroitin 6) sulfotransferase 3 (CHST3), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu23151C NM_004273 Homo sapiens carbohydrate (chondroitin 6) sulfotransferase 3 (CHST3), mRNA. Customized vector On-demand 7-9 $269.00
OHu23151C XM_006718075 PREDICTED: Homo sapiens carbohydrate (chondroitin 6) sulfotransferase 3 (CHST3), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol CHST3
Entrez Gene ID 9469
Full Name carbohydrate (chondroitin 6) sulfotransferase 3
Synonyms C6ST, C6ST1, HSD
General protein information
Preferred Names
carbohydrate sulfotransferase 3
Names
carbohydrate sulfotransferase 3
GST-0
C6ST-1
chondroitin 6-O-sulfotransferase 1
galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0
NP_004264.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q22.1

Summary This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009].
Disorder

MIM: 603799

Spondyloepiphyseal dysplasia with congenital joint dislocations,

mRNA Protein Product Sequence Price Select
NM_004273, 224493825 NP_004264, 19923281 carbohydrate sulfotransferase 3 ORF Sequence $550.00
XM_006718075, 578820025 XP_006718138, 578820026 carbohydrate sulfotransferase 3 isoform X1 ORF Sequence $550.00
KEGG
hsa00532Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
WikiPathways
WP702metapathway biotransformation
BIOCYC
HUMAN_PWY-6569chondroitin sulfate biosynthesis
META_PWY-6567chondroitin sulfate biosynthesis (late stages)
HUMAN_PWY-6567chondroitin sulfate biosynthesis (late stages)
META_PWY-6569chondroitin sulfate biosynthesis
Reactome
REACT_474Metabolism of carbohydrates
REACT_111217Metabolism
REACT_147749MPS IIID - Sanfilippo syndrome D
REACT_147825MPS IV - Morquio syndrome A
REACT_147719MPS VI - Maroteaux-Lamy syndrome
REACT_147753MPS IIIA - Sanfilippo syndrome A
REACT_147739MPS IX - Natowicz syndrome
REACT_147860MPS IIIC - Sanfilippo syndrome C
REACT_147853Mucopolysaccharidoses
REACT_147734MPS II - Hunter syndrome
REACT_147788MPS IIIB - Sanfilippo syndrome B
REACT_147759MPS VII - Sly syndrome
REACT_147798MPS IV - Morquio syndrome B
REACT_147857MPS I - Hurler syndrome
REACT_116125Disease
REACT_121315Glycosaminoglycan metabolism
REACT_120989Chondroitin sulfate biosynthesis
REACT_121206Chondroitin sulfate/dermatan sulfate metabolism
REACT_200783Myoclonic epilepsy of Lafora
REACT_200833Glycogen storage diseases
Homo sapiens (human)CHST3NP_004264.2
Pan troglodytes (chimpanzee)CHST3XP_521690.1
Macaca mulatta (Rhesus monkey)CHST3XP_001106464.2
Canis lupus familiaris (dog)CHST3XP_003639041.1
Bos taurus (cattle)CHST3NP_001192524.1
Mus musculus (house mouse)Chst3NP_058083.2
Rattus norvegicus (Norway rat)Chst3NP_445860.1
Gallus gallus (chicken)CHST3NP_990452.1
Danio rerio (zebrafish)chst3bNP_001103846.1
Danio rerio (zebrafish)chst3aNP_001139043.1
Xenopus (Silurana) tropicalis (western clawed frog)chst3XP_002939563.2
Process
IDNameEvidence
GO:0005975carbohydrate metabolic processTAS
GO:0006790sulfur compound metabolic processIDA
GO:0030203glycosaminoglycan metabolic processTAS
GO:0030204chondroitin sulfate metabolic processTAS
GO:0030206chondroitin sulfate biosynthetic processIDA
GO:0030206chondroitin sulfate biosynthetic processTAS
GO:0043029T cell homeostasisIEA
GO:0044281small molecule metabolic processTAS
Component
IDNameEvidence
GO:0000139Golgi membraneTAS
GO:0016021integral component of membraneIEA
Function
IDNameEvidence
GO:0008146sulfotransferase activityTAS
GO:0008459chondroitin 6-sulfotransferase activityIDA
GO:0050698proteoglycan sulfotransferase activityIEA
GeneCards CHST3
UniProt Q7LGC8
Vega OTTHUMG00000018431
MIM 603799
Ensembl ENSG00000122863
HGNC 1971
HPRD 07052

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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