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NPEPPS aminopeptidase puromycin sensitive [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu08979 NM_006310 Homo sapiens aminopeptidase puromycin sensitive (NPEPPS), mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu50823 XM_006722187 PREDICTED: Homo sapiens aminopeptidase puromycin sensitive (NPEPPS), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu08979C NM_006310 Homo sapiens aminopeptidase puromycin sensitive (NPEPPS), mRNA. Customized vector On-demand 12-14 $329.00
OHu50823C XM_006722187 PREDICTED: Homo sapiens aminopeptidase puromycin sensitive (NPEPPS), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol NPEPPS
Entrez Gene ID 9520
Full Name aminopeptidase puromycin sensitive
Synonyms AAP-S, MP100, PSA
General protein information
Preferred Names
puromycin-sensitive aminopeptidase
Names
puromycin-sensitive aminopeptidase
metalloproteinase MP100
cytosol alanyl aminopeptidase
NP_006301.3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21

Summary This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008].
Disorder

MIM: 606793

mRNA Protein Product Sequence Price Select
NM_006310, 158937235 NP_006301, 158937236 puromycin-sensitive aminopeptidase ORF Sequence $750.00
XM_006722187, 578831674 XP_006722250, 578831675 puromycin-sensitive aminopeptidase isoform X1 ORF Sequence $700.00
Reactome
REACT_6900Immune System
REACT_75774Adaptive Immune System
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_75842Antigen processing: Ubiquitination & Proteasome degradation
Homo sapiens (human)NPEPPSNP_006301.3
Pan troglodytes (chimpanzee)NPEPPSXP_001173517.2
Macaca mulatta (Rhesus monkey)NPEPPSXP_001082709.2
Canis lupus familiaris (dog)NPEPPSXP_537659.4
Bos taurus (cattle)NPEPPSNP_001180088.1
Mus musculus (house mouse)NpeppsNP_032968.2
Rattus norvegicus (Norway rat)NpeppsNP_536320.1
Gallus gallus (chicken)NPEPPSXP_001234986.3
Danio rerio (zebrafish)npeppsNP_001157499.1
Drosophila melanogaster (fruit fly)PsaNP_728614.1
Caenorhabditis eleganspam-1NP_001023210.1
Arabidopsis thaliana (thale cress)APM1NP_195035.2
Xenopus (Silurana) tropicalis (western clawed frog)npeppsNP_001072690.1
Process
IDNameEvidence
GO:0000209protein polyubiquitinationTAS
GO:0002474antigen processing and presentation of peptide antigen via MHC class ITAS
GO:0006508proteolysisIEA
GO:0071456cellular response to hypoxiaIDA
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005829cytosolTAS
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0004177aminopeptidase activityIEA
GO:0008237metallopeptidase activityIEA
GO:0008270zinc ion bindingIEA
GeneCards NPEPPS
UniProt P55786
Vega OTTHUMG00000165471
MIM 606793
Ensembl ENSG00000141279
HGNC 7900
HPRD 07366

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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