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POLR1C polymerase (RNA) I polypeptide C, 30kDa [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_203290 Homo sapiens polymerase (RNA) I polypeptide C, 30kDa (POLR1C), mRNA. ORF Sequence $301.89
Peptide Services
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Gene Symbol POLR1C
Entrez Gene ID 9533
Full Name polymerase (RNA) I polypeptide C, 30kDa
Synonyms RPA39, RPA40, RPA5, RPAC1, TCS3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p21.1

Summary The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS). [provided by RefSeq, Mar 2011].
Disorder

MIM: 610060

Treacher Collins syndrome 3, 248390 (3)

mRNA Protein Product Sequence Price Select
NM_203290, 327365362 NP_976035, 42560246 DNA-directed RNA polymerases I and III subunit RPAC1 Full Length $392.37
ORF Sequence $301.89
KEGG
hsa04623Cytosolic DNA-sensing pathway
hsa_M00181RNA polymerase III, eukaryotes
hsa00240Pyrimidine metabolism
hsa05169Epstein-Barr virus infection
hsa03020RNA polymerase
hsa00230Purine metabolism
hsa_M00182RNA polymerase I, eukaryotes
WikiPathways
WP231TNF-alpha/NF-kB Signaling Pathway
Reactome
REACT_1913RNA Polymerase I Promoter Escape
REACT_1974RNA Polymerase I Promoter Clearance
REACT_1074RNA Polymerase I Transcription Termination
REACT_953RNA Polymerase I Transcription Initiation
REACT_22339RNA Polymerase III Abortive And Retractive Initiation
REACT_63RNA Polymerase III Transcription Termination
REACT_1371RNA Polymerase III Transcription
REACT_756RNA Polymerase III Chain Elongation
REACT_1309RNA Polymerase I Transcription
REACT_347RNA Polymerase III Transcription Initiation From Type 1 Promoter
REACT_571RNA Polymerase III Transcription Initiation From Type 3 Promoter
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_281RNA Polymerase III Transcription Initiation
REACT_2204RNA Polymerase I Chain Elongation
REACT_1036RNA Polymerase III Transcription Initiation From Type 2 Promoter
REACT_71Gene Expression
Homo sapiens (human)POLR1CNP_976035.1
Pan troglodytes (chimpanzee)POLR1CXP_001136605.2
Canis lupus familiaris (dog)POLR1CXP_532147.1
Bos taurus (cattle)POLR1CNP_001033213.1
Mus musculus (house mouse)Polr1cNP_033111.2
Rattus norvegicus (Norway rat)Polr1cNP_001008331.1
Gallus gallus (chicken)POLR1CXP_419502.1
Danio rerio (zebrafish)polr1cNP_956860.1
Drosophila melanogaster (fruit fly)CG3756NP_608885.1
Caenorhabditis elegansH43I07.2NP_504166.2
Arabidopsis thaliana (thale cress)ATRPAC42NP_176282.1
Arabidopsis thaliana (thale cress)RPAC43NP_176261.1
GeneCards POLR1C
UniProt O15160
MIM 610060
Ensembl ENSG00000171453
HGNC 20194
HPRD 09661

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
DNA-directed RNA polymerases I and III subunit RPAC1
Names
DNA-directed RNA polymerases I and III subunit RPAC1
AC40
RPC40
RNA polymerases I and III subunit AC1
DNA-directed RNA polymerase I subunit C
DNA-directed RNA polymerases I and III 40 kDa polypeptide

Interactant

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