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Sequence in raw or FASTA format:


Blast Method:


GDF3 growth differentiation factor 3 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_020634 Homo sapiens growth differentiation factor 3 (GDF3), mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

*Business Day

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Gene Symbol GDF3
Entrez Gene ID 9573
Full Name growth differentiation factor 3
Synonyms KFS3, MCOP7, MCOPCB6
General protein information
Preferred Names
growth/differentiation factor 3
growth/differentiation factor 3
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008].

MIM: 606522

Klippel-Feil syndrome 3, autosomal dominant, 613702 (3);

mRNA Protein Product Sequence Price Select
NM_020634, 10190669 NP_065685, 10190670 growth/differentiation factor 3 precursor ORF Sequence $269.00
Homo sapiens (human)GDF3NP_065685.1
Pan troglodytes (chimpanzee)GDF3XP_508988.2
Macaca mulatta (Rhesus monkey)GDF3XP_001112644.1
Canis lupus familiaris (dog)GDF3XP_534896.1
Bos taurus (cattle)GDF3XP_002687893.1
Mus musculus (house mouse)Gdf3NP_032134.2
Rattus norvegicus (Norway rat)Gdf3NP_001103141.1
Gallus gallus (chicken)GDF3NP_990542.1
Danio rerio (zebrafish)dvr1NP_571023.1
Xenopus (Silurana) tropicalis (western clawed frog)gdf3NP_001007905.1
Xenopus (Silurana) tropicalis (western clawed frog)gdf1NP_001016819.1
GO:0001501skeletal system developmentIMP
GO:0001654eye developmentIMP
GO:0001701in utero embryonic developmentIEA
GO:0002021response to dietary excessIEA
GO:0007165signal transductionIEA
GO:0007492endoderm developmentIEA
GO:0007498mesoderm developmentIEA
GO:0010453regulation of cell fate commitmentIDA
GO:0030514negative regulation of BMP signaling pathwayIDA
GO:0030903notochord developmentIEA
GO:0032525somite rostral/caudal axis specificationIEA
GO:0045605negative regulation of epidermal cell differentiationIDA
GO:0048859formation of anatomical boundaryIEA
GO:0090009primitive streak formationIEA
GO:0005615extracellular spaceIEA
GO:0005125cytokine activityIEA
GO:0008083growth factor activityIEA
GO:0019901protein kinase bindingIPI
GeneCards GDF3
UniProt Q9NR23
Vega OTTHUMG00000168433
MIM 606522
Ensembl ENSG00000184344
HGNC 4218
HPRD 05938

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the GDF3 gene?

The GDF3 gene provides instructions for making a protein that is part of the transforming growth factor beta (TGFβ) superfamily, which is a group of proteins that help control the growth and development of tissues throughout the body. Within the TGFβ superfamily, the GDF3 protein belongs to the bone morphogenetic protein family, which is involved in regulating the growth and maturation (differentiation) of bone and cartilage. Cartilage is a tough but flexible tissue that makes up much of the skeleton during early development. The proteins in this family are regulators of cell growth and differentiation in both embryonic and adult tissue. While the GDF3 gene is known to be involved in bone and cartilage development, its exact role is unclear.


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