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GDF3 growth differentiation factor 3 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18012 NM_020634 Homo sapiens growth differentiation factor 3 (GDF3), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu18012C NM_020634 Homo sapiens growth differentiation factor 3 (GDF3), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol GDF3
Entrez Gene ID 9573
Full Name growth differentiation factor 3
Synonyms KFS3, MCOP7, MCOPCB6
General protein information
Preferred Names
growth/differentiation factor 3
Names
growth/differentiation factor 3
GDF-3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13.1

Summary The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008].
Disorder

MIM: 606522

Klippel-Feil syndrome 3, autosomal dominant, 613702 (3);

mRNA Protein Product Sequence Price Select
NM_020634, 10190669 NP_065685, 10190670 growth/differentiation factor 3 precursor ORF Sequence $269.00
Homo sapiens (human)GDF3NP_065685.1
Pan troglodytes (chimpanzee)GDF3XP_508988.2
Macaca mulatta (Rhesus monkey)GDF3XP_001112644.1
Canis lupus familiaris (dog)GDF3XP_534896.1
Bos taurus (cattle)GDF3XP_002687893.1
Mus musculus (house mouse)Gdf3NP_032134.2
Rattus norvegicus (Norway rat)Gdf3NP_001103141.1
Gallus gallus (chicken)GDF3NP_990542.1
Danio rerio (zebrafish)dvr1NP_571023.1
Xenopus (Silurana) tropicalis (western clawed frog)gdf3NP_001007905.1
Xenopus (Silurana) tropicalis (western clawed frog)gdf1NP_001016819.1
Process
IDNameEvidence
GO:0001501skeletal system developmentIMP
GO:0001654eye developmentIMP
GO:0001701in utero embryonic developmentIEA
GO:0002021response to dietary excessIEA
GO:0007165signal transductionIEA
GO:0007492endoderm developmentIEA
GO:0007498mesoderm developmentIEA
GO:0010453regulation of cell fate commitmentIDA
GO:0030514negative regulation of BMP signaling pathwayIDA
GO:0030903notochord developmentIEA
GO:0032525somite rostral/caudal axis specificationIEA
GO:0040007growthIEA
GO:0045605negative regulation of epidermal cell differentiationIDA
GO:0048859formation of anatomical boundaryIEA
GO:0090009primitive streak formationIEA
Component
IDNameEvidence
GO:0005615extracellular spaceIEA
GO:0005737cytoplasmIDA
Function
IDNameEvidence
GO:0005125cytokine activityIEA
GO:0008083growth factor activityIEA
GO:0019901protein kinase bindingIPI
GeneCards GDF3
UniProt Q9NR23
Vega OTTHUMG00000168433
MIM 606522
Ensembl ENSG00000184344
HGNC 4218
HPRD 05938

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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