GDF3 growth differentiation factor 3 [Homo sapiens (human)]
| Gene Symbol | GDF3 |
| Entrez Gene ID | 9573 |
| Full Name | growth differentiation factor 3 |
| Synonyms | KFS3, MCOP7, MCOPCB6 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
12 12p13.1 |
| Summary | The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq]. |
| Disorder | MIM: 606522 Klippel-Feil syndrome 3, autosomal dominant, 613702 (3); |
| mRNA | NM_020634, 10190669 |
| Protein | NP_065685, 10190670 |
| Product | growth/differentiation factor 3 precursor |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | GDF3 | NP_065685.1 |
| Pan troglodytes (chimpanzee) | GDF3 | XP_508988.2 |
| Canis lupus familiaris (dog) | GDF3 | XP_534896.1 |
| Bos taurus (cattle) | LOC786521 | XP_001254181.1 |
| Bos taurus (cattle) | LOC504995 | XP_581211.1 |
| Mus musculus (house mouse) | Gdf3 | NP_032134.2 |
| Rattus norvegicus (Norway rat) | Gdf3 | XP_575661.1 |
| Gallus gallus (chicken) | GDF3 | NP_990542.1 |
| Danio rerio (zebrafish) | dvr1 | NP_571023.1 |
| ID | Name | Evidence |
| GO:0001501 | skeletal system development | IMP |
| GO:0001654 | eye development | IMP |
| GO:0001701 | in utero embryonic development | IEA |
| GO:0002021 | response to dietary excess | IEA |
| GO:0007492 | endoderm development | IEA |
| GO:0007498 | mesoderm development | IEA |
| GO:0030903 | notochord development | IEA |
| GO:0032525 | somite rostral/caudal axis specification | IEA |
| GO:0040007 | growth | IEA |
| GO:0048859 | formation of anatomical boundary | IEA |
| GO:0090009 | primitive streak formation | IEA |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | IEA |
| GO:0005615 | extracellular space | IEA |
Function
| ID | Name | Evidence |
| GO:0005125 | cytokine activity | IEA |
| GO:0008083 | growth factor activity | IEA |
Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.
 |
Secured Online Quotation |
 |
Email: gene@genscript.com |
 |
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188 |
 |
Fax: 1-732-210-0262 1-732-885-5878 |