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RBM8A RNA binding motif protein 8A [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu20462D NM_005105 Homo sapiens RNA binding motif protein 8A (RBM8A), mRNA. pcDNA3.1-C-(k)DYK In-stock 5-7 Starting from $99
OHu20462C NM_005105 Homo sapiens RNA binding motif protein 8A (RBM8A), mRNA. Customized vector In-stock 5-7 Starting from $99

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Gene Symbol RBM8A
Entrez Gene ID 9939
Full Name RNA binding motif protein 8A
Synonyms BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1
General protein information
Preferred Names
RNA-binding protein 8A
RNA-binding protein 8A
binder of OVCA1-1
ribonucleoprotein RBM8
RNA-binding protein Y14
ribonucleoprotein RBM8A
RNA binding motif protein 8B
RNA-binding motif protein 8A
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013].

MIM: 605313

mRNA Protein Product Sequence Price Select
NM_005105, 525345282 NP_005096, 4826972 RNA-binding protein 8A ORF Sequence $159.00
hsa03013RNA transport
hsa03015mRNA surveillance pathway
hsa_M00430Exon junction complex (EJC)
REACT_71Gene Expression
REACT_1281Transport of Mature Transcript to Cytoplasm
REACT_467mRNA Splicing - Major Pathway
REACT_1849mRNA 3'-end processing
REACT_1735mRNA Splicing
REACT_1597Transport of Mature mRNA derived from an Intron-Containing Transcript
REACT_1366RNA Polymerase II Transcription
REACT_894RNA Polymerase II Transcription Termination
REACT_387Cleavage of Growing Transcript in the Termination Region
REACT_125Processing of Capped Intron-Containing Pre-mRNA
REACT_75822Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
REACT_75886Nonsense-Mediated Decay (NMD)
Homo sapiens (human)RBM8ANP_005096.1
Pan troglodytes (chimpanzee)RBM8AXP_001162472.1
Canis lupus familiaris (dog)RBM8AXP_533035.1
Bos taurus (cattle)RBM8ANP_001030401.1
Mus musculus (house mouse)Rbm8aNP_001095877.1
Rattus norvegicus (Norway rat)Rbm8aNP_001258067.1
Danio rerio (zebrafish)rbm8aNP_001013363.1
Drosophila melanogaster (fruit fly)tsuNP_610454.2
Caenorhabditis elegansrnp-4NP_497891.1
Arabidopsis thaliana (thale cress)Y14NP_564591.1
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIMP
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTAS
GO:0000381regulation of alternative mRNA splicing, via spliceosomeIMP
GO:0000398mRNA splicing, via spliceosomeIC
GO:0000398mRNA splicing, via spliceosomeTAS
GO:0006366transcription from RNA polymerase II promoterTAS
GO:0006369termination of RNA polymerase II transcriptionTAS
GO:0006406mRNA export from nucleusTAS
GO:0006417regulation of translationIEA
GO:0008380RNA splicingTAS
GO:0010467gene expressionTAS
GO:0016070RNA metabolic processTAS
GO:0016071mRNA metabolic processTAS
GO:0031124mRNA 3'-end processingTAS
GO:0016607nuclear speckIEA
GO:0035145exon-exon junction complexIDA
GO:0071013catalytic step 2 spliceosomeIDA
GO:0000166nucleotide bindingIEA
GO:0003723RNA bindingNAS
GO:0003729mRNA bindingNAS
GO:0005515protein bindingIPI
GO:0044822poly(A) RNA bindingIDA
GeneCards RBM8A
UniProt Q9Y5S9
Vega OTTHUMG00000013736
MIM 605313
Ensembl ENSG00000131795
HGNC 9905
HPRD 05609

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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