Homo sapiens albumin (ALB), mRNA.

Summary
Sequence
Translation
SNP
Other Variants
PubMed

RefSeq Version	NM_000477.5, 215982788
Length	2264 bp
Structure	linear
Update Date	10-APR-2011
Organism	Homo sapiens (human)
Definition	Homo sapiens albumin (ALB), mRNA.
Product	serum albumin preproprotein
Comment	Summary: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq].

RefSeq	NP_000468.1
CDS	74..1903
Exon (1)	1..152
Exon (2)	1..152
Exon (3)	153..210
Exon (4)	211..343
Exon (5)	344..555
Exon (6)	556..688
Exon (7)	689..786
Exon (8)	787..916
Exon (9)	917..1131
Exon (10)	1132..1264
Exon (11)	1265..1362
Exon (12)	1363..1501
Exon (13)	1502..1725
Exon (14)	1726..1858
Exon (15)	1859..1926
Exon (16)	1927..2247
Translation	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYAR RHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVV LNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV AASQAALGL Order your protein of interest with our Guaranteed or It's Free Service now! For details, please click here.

Position	Chain	Variation	Link
102	+	c, t	dbSNP:11538209
104	+	a, t	dbSNP:11538213
140	+	c, t	dbSNP:80008208
141	+	a, g	dbSNP:72552709
144	+	a, c, g, t	dbSNP:74821926
147	+	a, t	dbSNP:75353611
154	+	a, c, g	dbSNP:76285851
175	+	g, t	dbSNP:11538230
198	+	a, g	dbSNP:11538232
208	+	a, c	dbSNP:17854154
209..210	+	g, t	dbSNP:17855652
239	+	c, t	dbSNP:75470261
288	+	a, t	dbSNP:59066571
301..302	+	, at	dbSNP:75152012
307	+	c, t	dbSNP:11538229
315	+	a, g	dbSNP:11538221
323	+	a, g	dbSNP:77050410
332	+	a, g	dbSNP:78574148
339	+	c, t	dbSNP:11538216
340	+	a, t	dbSNP:59439476
342	+	c, t	dbSNP:77892378
380	+	a, g	dbSNP:11538226
389	+	a, g	dbSNP:80296402
457	+	a, g	dbSNP:11538225
485	+	c, g, t	dbSNP:77238412
500	+	a, g	dbSNP:75522063
510	+	a, t	dbSNP:77752336
528	+	a, g	dbSNP:80095457
545	+	c, t	dbSNP:11538217
564	+	a, g	dbSNP:78283180
611	+	c, t	dbSNP:116782027
655..656	+	a, g	dbSNP:11538219
670	+	a, t	dbSNP:77756256
675	+	g, t	dbSNP:77656691
685	+	a, g	dbSNP:58639526
702	+	a, g	dbSNP:58624704
712..713	+	a, g	dbSNP:11538220
715	+	g, t	dbSNP:17400586
716	+	a, g	dbSNP:3210154
717	+	c, t	dbSNP:3204504
726	+	c, g	dbSNP:11538228
732	+	a, t	dbSNP:3210163
787	+	a, g	dbSNP:76454301
798	+	a, c, g	dbSNP:75002628
818	+	a, c	dbSNP:79804069
863	+	a, g	dbSNP:79377490
874	+	a, g	dbSNP:11538224
875..876	+	, a	dbSNP:36067576
875	+	g, t	dbSNP:78340021
945	+	, a	dbSNP:77449454
948	+	a, g	dbSNP:80002911
951	+	a, g	dbSNP:79744198
964	+	c, t	dbSNP:56167251
973	+	c, g	dbSNP:74718349
1061	+	a, g	dbSNP:11538222
1084	+	g, t	dbSNP:72552710
1086	+	a, g, t	dbSNP:76242087
1097	+	a, g	dbSNP:11538223
1099	+	c, g	dbSNP:77544362
1103	+	a, g	dbSNP:78953271
1106	+	a, g	dbSNP:72552711
1131	+	c, t	dbSNP:79568748
1142	+	a, g	dbSNP:77354753
1205	+	a, g	dbSNP:76593094
1217	+	a, g	dbSNP:75791663
1222	+	c, g, t	dbSNP:75069738
1237	+	a, g	dbSNP:17854155
1238	+	c, g	dbSNP:77187142
1239	+	a, t	dbSNP:78538497
1250	+	c, t	dbSNP:11538215
1259	+	a, g	dbSNP:78166690
1268	+	a, c, g	dbSNP:77514449
1271	+	a, c, g	dbSNP:79047363
1289	+	a, g	dbSNP:76483862
1290	+	a, t	dbSNP:11538214
1298	+	c, t	dbSNP:75946332
1303	+	c, t	dbSNP:35683929
1348	+	a, c	dbSNP:78297318
1373	+	c, t	dbSNP:78575701
1433	+	c, t	dbSNP:11538212
1496	+	g, t	dbSNP:1140449
1498	+	c, t	dbSNP:1140450
1500..1501	+	a, g	dbSNP:77893506
1519	+	c, t	dbSNP:59597814
1541	+	a, g	dbSNP:1063469
1555	+	c, t	dbSNP:11538231
1578	+	c, t	dbSNP:60826059
1580	+	a, g	dbSNP:80259813
1598	+	c, t	dbSNP:78696173
1600	+	a, t	dbSNP:17853503
1625	+	a, g	dbSNP:75920790
1646	+	a, g	dbSNP:75523493
1658	+	a, g	dbSNP:74826639
1663	+	a, g	dbSNP:17853250
1681	+	c, t	dbSNP:56042353
1683	+	, t	dbSNP:77081291
1694	+	c, t	dbSNP:11538227
1741	+	c, g, t	dbSNP:962004
1742	+	a, g	dbSNP:78284052
1751	+	a, g	dbSNP:77645174
1753	+	c, g	dbSNP:57636959
1763	+	a, c	dbSNP:61579038
1766	+	a, g	dbSNP:80345158
complement(1777)	-	t, c	dbSNP:11538206
1778	+	a, g	dbSNP:72552712
complement(1788)	-	t, a	dbSNP:11538208
1794	+	a, c, g	dbSNP:79738788
1799	+	a, g	dbSNP:115943356
1823	+	a, g	dbSNP:76671808
1832	+	a, g	dbSNP:76587671
1838	+	a, g	dbSNP:75709682
1844	+	, t	dbSNP:74674594
1853	+	a, g	dbSNP:79228041
1859	+	, largedeletion	dbSNP:71740173
1862	+	a, g	dbSNP:80106970
1867	+	a, c, t	dbSNP:75738598
1867	+	, a	dbSNP:75000326
1883	+	, c	dbSNP:77158239
1922	+	c, t	dbSNP:61332165
1923..1926	+	, largedeletion	dbSNP:71756732
1962..1963	+	, g	dbSNP:35283985
complement(1991)	-	c, a	dbSNP:11538204
2068	+	a, t	dbSNP:3205432
2071	+	a, t	dbSNP:3211553
complement(2092)	-	t, a	dbSNP:77580720

Gene Symbol	ALB
Gene Synonym	DKFZp779N1935; PRO0883; PRO0903; PRO1341
Chromosome	4
Locus Map	4q13.3
All Transcripts	NM_000477

Title	Diagnosis of ischemic heart disease using CK-MB, troponin-I and ischemia modified albumin .
Author	Dawie,J., Chawla,R., Worku,Y. and Azazh,A.
Journal	Ethiop. Med. J. 49 (1), 25-33 (2011)
Title	Mutations and polymorphisms of the gene of the major human blood protein, serum albumin .
Author	Minchiotti,L., Galliano,M., Kragh-Hansen,U. and Peters,T. Jr.
Journal	Hum. Mutat. 29 (8), 1007-1016 (2008)
Title	Crystal structure of human serum albumin at 2.5 A resolution .
Author	Sugio,S., Kashima,A., Mochizuki,S., Noda,M. and Kobayashi,K.
Journal	Protein Eng. 12 (6), 439-446 (1999)
Title	Atomic structure and chemistry of human serum albumin .
Author	He,X.M. and Carter,D.C.
Journal	Nature 358 (6383), 209-215 (1992)
Title	Structure of human serum albumin .
Author	Carter,D.C. and He,X.M.
Journal	Science 249 (4966), 302-303 (1990)
Title	The human albumin gene. Characterization of the 5' and 3' flanking regions and the polymorphic gene transcripts .
Author	Urano,Y., Watanabe,K., Sakai,M. and Tamaoki,T.
Journal	J. Biol. Chem. 261 (7), 3244-3251 (1986)
Title	The human serum albumin gene: structure of a unique locus .
Author	Hawkins,J.W. and Dugaiczyk,A.
Journal	Gene 19 (1), 55-58 (1982)
Title	Nucleotide sequence and the encoded amino acids of human serum albumin mRNA .
Author	Dugaiczyk,A., Law,S.W. and Dennison,O.E.
Journal	Proc. Natl. Acad. Sci. U.S.A. 79 (1), 71-75 (1982)
Title	Limited pepsin digestion of human plasma albumin .
Author	Heaney-Kieras,J. and King,T.P.
Journal	J. Biol. Chem. 252 (12), 4326-4329 (1977)
Title	Complete amino acid sequence of human serum albumin .
Author	Meloun,B., Moravek,L. and Kostka,V.
Journal	FEBS Lett. 58 (1), 134-137 (1975)

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RefSeq Accession	Definition	Sequence	Price	Select
NM_000477	Homo sapiens albumin (ALB), mRNA.	Full Lenth	$656.56
NM_000477	Homo sapiens albumin (ALB), mRNA.	ORF Sequence	$530.70