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Homo sapiens ribosomal protein S13 (RPS13), mRNA.


RefSeq Accession Definition Services Price Order
NM_001017 Homo sapiens ribosomal protein S13 (RPS13), mRNA. ORF Sequence $159.00
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RefSeq Version NM_001017.2, 14591910
Length 529 bp
Structure linear
Update Date 17-APR-2013
Organism Homo sapiens (human)
Definition Homo sapiens ribosomal protein S13 (RPS13), mRNA.
Product 40S ribosomal protein S13
Comment

Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S15P family of ribosomal proteins. It is located in the cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps in ribosome assembly. This gene is co-transcribed with two U14 small nucleolar RNA genes, which are located in its third and fifth introns. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].

RefSeq NP_001008.1
CDS 33..488
Misc Feature(1)1
Misc Feature(2)1
Misc Feature(3)7
Misc Feature(4)33..212
Misc Feature(5)33..212
Misc Feature(6)42..485
Misc Feature(7)111..113
Misc Feature(8)144..146
Misc Feature(9)144..146
Misc Feature(10)240..467
Misc Feature(11)order(243..245,282..284,291..293,312..314,324..326,
Misc Feature(12)order(297..299,306..311,318..320,327..329,447..449,
Misc Feature(13)order(387..389,399..401,462..467)
Misc Feature(14)414..416
Misc Feature(15)417..419
Exon (1)1..55
Gene:RPS13
Gene Synonym:S13
Exon (2)56..104
Gene:RPS13
Gene Synonym:S13
Exon (3)105..183
Gene:RPS13
Gene Synonym:S13
Exon (4)184..353
Gene:RPS13
Gene Synonym:S13
Exon (5)354..454
Gene:RPS13
Gene Synonym:S13
Exon (6)455..529
Gene:RPS13
Gene Synonym:S13
Translation MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGV AQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIES RIHRLARYYKTKRVLPPNWKYESSTASALVA
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Position Chain Variation Link
complement(8)-g, adbSNP:78520678
complement(38)-c, adbSNP:201083860
complement(42)-t, cdbSNP:142912098
complement(86)-dbSNP:
complement(86)-t, cdbSNP:11550522
complement(89)-t, cdbSNP:113610512
complement(121)-dbSNP:
complement(121)-g, adbSNP:138459373
complement(215)-dbSNP:
complement(215)-t, adbSNP:1804352
complement(265)-t, cdbSNP:150106605
complement(291..292)-, tdbSNP:36097163
complement(320)-g, adbSNP:185336922
complement(323)-t, cdbSNP:11050
complement(331)-c, adbSNP:1804354
complement(359)-dbSNP:
complement(359)-g, adbSNP:1804348
complement(364)-g, cdbSNP:140723889
complement(374)-t, cdbSNP:11550521
complement(383)-t, g, c, adbSNP:1059640
complement(384..385)-g, adbSNP:11550525
complement(384)-g, adbSNP:3200417
complement(400)-c, adbSNP:11550526
complement(416)-g, adbSNP:190655000
complement(452)-t, cdbSNP:146930376
complement(501)-dbSNP:
complement(501)-t, adbSNP:147452342
Gene SymbolRPS13
Gene SynonymS13
Chromosome11
Locus Map11p15
All Transcripts
RefSeq Accession Definition Sequence Price Select
NM_001017 Homo sapiens ribosomal protein S13 (RPS13), mRNA. Full Length $159.00
ORF Sequence $159.00
Title [Binding of human ribosomal protein S13 to the central domain of 18S rRNA] .
Author Ivanov,A.V., Malygin,A.A. and Karpova,G.G.
Journal Mol. Biol. (Mosk.) 45 (6), 1046-1054 (2011)
Title Human ribosomal protein S13 promotes gastric cancer growth through down-regulating p27(Kip1) .
Author Guo,X., Shi,Y., Gou,Y., Li,J., Han,S., Zhang,Y., Huo,J., Ning,X., Sun,L., Chen,Y., Sun,S. and Fan,D.
Journal J. Cell. Mol. Med. 15 (2), 296-306 (2011)
Title Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism .
Author Malygin,A.A., Parakhnevitch,N.M., Ivanov,A.V., Eperon,I.C. and Karpova,G.G.
Journal Nucleic Acids Res. 35 (19), 6414-6423 (2007)
Title Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes .
Author Yu,Y., Ji,H., Doudna,J.A. and Leary,J.A.
Journal Protein Sci. 14 (6), 1438-1446 (2005)
Title Human ribosomal protein S13: cloning, expression, refolding, and structural stability .
Author Malygin,A., Parakhnevitch,N. and Karpova,G.
Journal Biochim. Biophys. Acta 1747 (1), 93-97 (2005)
Title U14 snoRNAs are encoded in introns of human ribosomal protein S13 gene .
Author Kenmochi,N., Higa,S., Yoshihama,M. and Tanaka,T.
Journal Biochem. Biophys. Res. Commun. 228 (2), 371-374 (1996)
Title Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry .
Author Vladimirov,S.N., Ivanov,A.V., Karpova,G.G., Musolyamov,A.K., Egorov,T.A., Thiede,B., Wittmann-Liebold,B. and Otto,A.
Journal Eur. J. Biochem. 239 (1), 144-149 (1996)
Title Structure and evolution of mammalian ribosomal proteins .
Author Wool,I.G., Chan,Y.L. and Gluck,A.
Journal Biochem. Cell Biol. 73 (11-12), 933-947 (1995)
Title Cloning and analysis of the human S13 ribosomal protein cDNA .
Author Chadeneau,C., LeMoullac,B. and Denis,M.G.
Journal Nucleic Acids Res. 21 (12), 2945 (1993)
Title The primary structure of rat ribosomal protein S13 .
Author Suzuki,K., Olvera,J. and Wool,I.G.
Journal Biochem. Biophys. Res. Commun. 171 (2), 519-524 (1990)

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