Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), mRNA.
| RefSeq Version | NM_002123.3, 150418001 |
| Length | 1241 bp |
| Structure | linear |
| Update Date | 16-APR-2011 |
| Organism | Homo sapiens (human) |
| Definition | Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), mRNA. |
| Product | HLA class II histocompatibility antigen, DQ beta 1 chain precursor |
| Comment | Summary: HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq]. |
| RefSeq | NP_002114.3 |
| CDS | 83..868 | Exon (1) | 1..191 | Exon (2) | 1..191 | Exon (3) | 192..461 | Exon (4) | 462..743 | Exon (5) | 744..854 | Exon (6) | 855..1224 |
| Translation | MSWKKALRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVT
RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFR
GILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLI
RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVL
GLIFLGLGLIIRQRSQKGLLH
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| Position | Chain | Variation | Link |
| 20 | + | c, g | dbSNP:3210146 |
| complement(20) | - | g, c | dbSNP:117829618 |
| complement(41) | - | g, a | dbSNP:111933157 |
| complement(41) | - | g, a | dbSNP:67147537 |
| 42 | + | a, g | dbSNP:1049070 |
| 48 | + | a, t | dbSNP:3210147 |
| complement(60..62) | - | , cag | dbSNP:67819715 |
| complement(61..62) | - | , cag | dbSNP:9280060 |
| complement(62..64) | - | , agc | dbSNP:71789649 |
| 62 | + | a, g | dbSNP:1049053 |
| complement(62) | - | t, c | dbSNP:75161319 |
| complement(73) | - | g, a | dbSNP:117410658 |
| 80 | + | a, g | dbSNP:1049055 |
| complement(94) | - | t, c | dbSNP:9274522 |
| 98 | + | g, t | dbSNP:1049056 |
| 112 | + | c, t | dbSNP:1049072 |
| 117 | + | a, g | dbSNP:1049057 |
| complement(117) | - | t, c | dbSNP:76331164 |
| 126 | + | a, c, t | dbSNP:3189152 |
| complement(128) | - | g, c | dbSNP:116896182 |
| 136 | + | c, g, t | dbSNP:1049058 |
| 149 | + | g, t | dbSNP:3891176 |
| 154 | + | c, g | dbSNP:1049059 |
| 161 | + | a, g, t | dbSNP:1049060 |
| complement(164..165) | - | ag, ga | dbSNP:67851506 |
| 164 | + | c, t | dbSNP:1049061 |
| 165 | + | c, t | dbSNP:1049062 |
| 166 | + | a, g | dbSNP:1130373 |
| 167 | + | c, g | dbSNP:1130366 |
| 185 | + | c, t | dbSNP:12722106 |
| 203 | + | c, t | dbSNP:12722107 |
| complement(204) | - | t, a | dbSNP:9274407 |
| complement(204) | - | t, a | dbSNP:77051381 |
| complement(204) | - | t, a | dbSNP:78476585 |
| complement(205) | - | t, g | dbSNP:111588946 |
| 211 | + | a, t | dbSNP:56173496 |
| 216 | + | c, g | dbSNP:1130375 |
| 218 | + | a, c | dbSNP:1130368 |
| 219 | + | c, g | dbSNP:41556424 |
| 235 | + | c, t | dbSNP:76033807 |
| 235 | + | c, t | dbSNP:3204373 |
| 238 | + | c, g | dbSNP:72558170 |
| 241 | + | a, c, g | dbSNP:1049079 |
| 246 | + | g, t | dbSNP:41540813 |
| complement(253..255) | - | ccc, aga | dbSNP:74184882 |
| 253 | + | g, t | dbSNP:1140310 |
| 254 | + | c, g, t | dbSNP:12722115 |
| 255 | + | a, g, t | dbSNP:1049066 |
| 257 | + | c, g | dbSNP:41563539 |
| 259 | + | a, g | dbSNP:1049068 |
| complement(259) | - | t, c | dbSNP:79502177 |
| complement(261) | - | g, c | dbSNP:9274405 |
| 263 | + | a, t | dbSNP:41553112 |
| 266 | + | a, c, t | dbSNP:1049069 |
| 266 | + | c, t | dbSNP:77080306 |
| complement(267) | - | t, c | dbSNP:9274403 |
| 277 | + | c, t | dbSNP:45496594 |
| 279 | + | a, c, g | dbSNP:75769070 |
| complement(283) | - | t, c | dbSNP:9274402 |
| 287 | + | a, g, t | dbSNP:1130370 |
| complement(288) | - | t, a | dbSNP:9274400 |
| 290 | + | a, g | dbSNP:45519640 |
| 291 | + | c, t | dbSNP:1063318 |
| 292 | + | a, g | dbSNP:1049082 |
| 312 | + | a, g | dbSNP:1049083 |
| complement(315) | - | t, a | dbSNP:9274398 |
| complement(318) | - | t, a | dbSNP:9274397 |
| 319 | + | c, t | dbSNP:1049073 |
| 322 | + | c, g | dbSNP:3210148 |
| 324 | + | c, t | dbSNP:41558214 |
| 325 | + | a, g | dbSNP:1049074 |
| 331 | + | c, g | dbSNP:41561518 |
| complement(333) | - | g, a | dbSNP:9274395 |
| 336 | + | a, t | dbSNP:1140313 |
| 342 | + | a, c, g, t | dbSNP:1130380 |
| 343 | + | c, g | dbSNP:41557617 |
| 345 | + | c, t | dbSNP:1130381 |
| 347 | + | a, g | dbSNP:41552812 |
| 348 | + | a, c, g, t | dbSNP:1071637 |
| 349 | + | c, t | dbSNP:1140314 |
| 356 | + | a, t | dbSNP:41562414 |
| 358 | + | c, t | dbSNP:41543717 |
| 364 | + | c, t | dbSNP:1130382 |
| 367 | + | c, g | dbSNP:41556215 |
| complement(376) | - | t, g | dbSNP:9274390 |
| complement(377) | - | t, c | dbSNP:9274389 |
| 378 | + | a, t | dbSNP:41563814 |
| 386 | + | a, g | dbSNP:1130386 |
| 387 | + | a, g | dbSNP:41563819 |
| 389 | + | a, g | dbSNP:1130390 |
| complement(390) | - | t, g | dbSNP:9274387 |
| complement(391) | - | t, g | dbSNP:9274386 |
| 394 | + | a, g | dbSNP:3204379 |
| 398 | + | g, t | dbSNP:1130385 |
| 399 | + | a, c | dbSNP:1130387 |
| complement(399) | - | tc, ga | dbSNP:74195786 |
| complement(401) | - | g, c, a | dbSNP:9274384 |
| 408 | + | c, g | dbSNP:1130392 |
| 409 | + | a, c, g | dbSNP:1130389 |
| 412 | + | a, g | dbSNP:1130391 |
| 428 | + | c, g | dbSNP:1140316 |
| 431 | + | g, t | dbSNP:1140317 |
| complement(435) | - | t, g, c | dbSNP:9274380 |
| complement(437) | - | g, a | dbSNP:9274379 |
| 438 | + | a, t | dbSNP:17412833 |
| 443 | + | a, g | dbSNP:1140318 |
| 444 | + | c, g | dbSNP:1140319 |
| 447 | + | c, t | dbSNP:1140320 |
| 449 | + | c, t | dbSNP:1130397 |
| 455 | + | a, c | dbSNP:1140321 |
| 458 | + | a, c | dbSNP:1140322 |
| complement(462) | - | , tc | dbSNP:9282131 |
| complement(463) | - | , g, a | dbSNP:9274030 |
| complement(464) | - | , t, c | dbSNP:9274029 |
| 465 | + | , g | dbSNP:41546916 |
| complement(466) | - | , t, c | dbSNP:9282130 |
| 467 | + | , g | dbSNP:41542716 |
| 468 | + | , c | dbSNP:41550312 |
| 469 | + | , c | dbSNP:41543319 |
| 470 | + | , c | dbSNP:41542118 |
| complement(471) | - | , t, a | dbSNP:9274028 |
| 472 | + | , c | dbSNP:41560717 |
| 473 | + | , a | dbSNP:41545112 |
| complement(474) | - | , t, c | dbSNP:9274027 |
| complement(475) | - | , g, a | dbSNP:9274026 |
| complement(476) | - | , g, c | dbSNP:9274025 |
| 477 | + | , a | dbSNP:41558012 |
| 478 | + | , c | dbSNP:41562015 |
| complement(479) | - | , tgt, g | dbSNP:9282129 |
| 480 | + | , a | dbSNP:41561417 |
| complement(481) | - | , g, a | dbSNP:9274024 |
| 482 | + | , c | dbSNP:41546013 |
| 483 | + | , t | dbSNP:41560420 |
| complement(484) | - | , g, c | dbSNP:9274023 |
| complement(485) | - | g, a | dbSNP:9274022 |
| complement(486) | - | g, c | dbSNP:9274021 |
| complement(487) | - | t, c | dbSNP:9274020 |
| complement(489..490) | - | , agca | dbSNP:9282128 |
| complement(492..493) | - | , a | dbSNP:9282127 |
| complement(500) | - | , c, a | dbSNP:9274019 |
| complement(501) | - | g, a | dbSNP:9274018 |
| complement(502) | - | g, a | dbSNP:9274017 |
| complement(504..505) | - | , g | dbSNP:9280021 |
| complement(507) | - | t, a | dbSNP:9274016 |
| complement(511) | - | g, c | dbSNP:9274015 |
| complement(513) | - | , t | dbSNP:9280020 |
| complement(515) | - | t, g | dbSNP:9274014 |
| complement(517) | - | g, c | dbSNP:9274013 |
| complement(518) | - | t, g | dbSNP:9274012 |
| complement(520) | - | g, c | dbSNP:9274011 |
| complement(521) | - | t, g | dbSNP:9274010 |
| complement(522) | - | t, a | dbSNP:9274009 |
| complement(523) | - | t, c | dbSNP:9274008 |
| 524 | + | a, g | dbSNP:1049100 |
| complement(524) | - | t, c | dbSNP:77166284 |
| complement(524) | - | t, c | dbSNP:77501678 |
| complement(527) | - | g, a | dbSNP:9274007 |
| complement(529) | - | g, c | dbSNP:9274006 |
| complement(530..531) | - | , t, g, c | dbSNP:9280019 |
| 532 | + | a, g | dbSNP:1063321 |
| complement(535) | - | c, a | dbSNP:9274005 |
| complement(536) | - | t, a | dbSNP:9274004 |
| complement(538) | - | t, c | dbSNP:9274003 |
| complement(541) | - | t, a | dbSNP:9274002 |
| complement(545) | - | , c, a, ga | dbSNP:9274001 |
| complement(546..547) | - | , a | dbSNP:9280017 |
| 551 | + | a, g | dbSNP:1049107 |
| complement(551) | - | t, c | dbSNP:77933679 |
| complement(551) | - | t, c | dbSNP:80055414 |
| complement(551) | - | t, c | dbSNP:80095453 |
| complement(552) | - | g, c | dbSNP:113231645 |
| 552 | + | , a, c, g | dbSNP:1063322 |
| complement(553) | - | g, c | dbSNP:9273999 |
| complement(554) | - | g, c | dbSNP:9273998 |
| complement(556) | - | g, c | dbSNP:76051596 |
| 556 | + | c, g | dbSNP:41542812 |
| complement(557..558) | - | , a | dbSNP:9280016 |
| complement(562) | - | t, g | dbSNP:9273997 |
| complement(563) | - | c, a | dbSNP:9273996 |
| complement(564) | - | c, a | dbSNP:9273995 |
| complement(565) | - | g, c | dbSNP:9273994 |
| 567 | + | a, g | dbSNP:41544112 |
| complement(567) | - | t, c | dbSNP:77483500 |
| complement(568) | - | c, a | dbSNP:9273993 |
| complement(571) | - | c, a | dbSNP:9273992 |
| complement(572) | - | c, a | dbSNP:9273991 |
| complement(574) | - | g, a | dbSNP:9273990 |
| 575 | + | c, t | dbSNP:63626961 |
| complement(576) | - | t, c | dbSNP:9273989 |
| complement(577) | - | g, c | dbSNP:9273988 |
| complement(578) | - | t, g | dbSNP:9273987 |
| complement(579) | - | t, g | dbSNP:9273986 |
| complement(580) | - | g, a | dbSNP:9273985 |
| complement(581) | - | g, c | dbSNP:9273984 |
| 582 | + | a, c, g | dbSNP:2647032 |
| 583 | + | c, t | dbSNP:1049086 |
| complement(583) | - | g, a | dbSNP:76725352 |
| complement(584) | - | g, c, a | dbSNP:9273981 |
| complement(586) | - | c, a | dbSNP:9273980 |
| complement(587) | - | c, a | dbSNP:9273979 |
| 589 | + | a, g | dbSNP:41543118 |
| complement(591..592) | - | , c | dbSNP:9280015 |
| 596 | + | a, g | dbSNP:74888860 |
| 596 | + | , a, g | dbSNP:1063323 |
| complement(597) | - | g, c | dbSNP:9273978 |
| 598 | + | c, t | dbSNP:1049087 |
| complement(598) | - | g, a | dbSNP:74356558 |
| complement(600) | - | t, c | dbSNP:9273976 |
| complement(602..603) | - | , ac | dbSNP:9280013 |
| complement(605..606) | - | , a | dbSNP:9280012 |
| complement(608) | - | t, a | dbSNP:9273975 |
| complement(612) | - | , t, g, a | dbSNP:9273974 |
| complement(613) | - | g, a | dbSNP:9273973 |
| complement(616) | - | t, g | dbSNP:9273972 |
| complement(617) | - | g, c | dbSNP:9273971 |
| complement(618) | - | t, a | dbSNP:9273970 |
| 619 | + | a, c, t | dbSNP:1049088 |
| complement(619) | - | g, a | dbSNP:76163881 |
| 619 | + | c, t | dbSNP:36233042 |
| complement(619) | - | g, a | dbSNP:79326791 |
| complement(621) | - | g, a | dbSNP:9273968 |
| complement(623) | - | t, c | dbSNP:9273967 |
| complement(625) | - | c, a | dbSNP:9273966 |
| complement(626) | - | t, c | dbSNP:9273965 |
| 628 | + | c, t | dbSNP:1049130 |
| complement(628) | - | g, a | dbSNP:17850864 |
| complement(628) | - | g, a | dbSNP:76605345 |
| complement(628) | - | g, a | dbSNP:75156092 |
| complement(630) | - | g, c | dbSNP:9273964 |
| complement(631..632) | - | , c | dbSNP:9282125 |
| complement(634) | - | t, g | dbSNP:9273963 |
| complement(635) | - | t, a | dbSNP:9273962 |
| complement(636) | - | c, a | dbSNP:9273961 |
| 640 | + | c, t | dbSNP:1049133 |
| complement(640) | - | g, a | dbSNP:79862994 |
| complement(642) | - | g, a | dbSNP:9273958 |
| complement(647..648) | - | , at | dbSNP:9280010 |
| complement(650) | - | g, c | dbSNP:9273957 |
| complement(654) | - | t, a | dbSNP:9273956 |
| 654 | + | a, t | dbSNP:75688764 |
| complement(657) | - | g, a | dbSNP:74577791 |
| complement(657) | - | g, a | dbSNP:9273955 |
| complement(658..659) | - | , a | dbSNP:9282124 |
| complement(661) | - | t, c | dbSNP:9273954 |
| complement(662) | - | g, c | dbSNP:9273953 |
| 662 | + | c, g | dbSNP:76620513 |
| complement(664) | - | t, g | dbSNP:9273952 |
| complement(665) | - | t, g | dbSNP:9273951 |
| complement(668) | - | t, g | dbSNP:9273950 |
| complement(670) | - | t, a | dbSNP:9273949 |
| complement(671..672) | - | , c | dbSNP:9282123 |
| complement(672) | - | g, a | dbSNP:9273948 |
| complement(672) | - | g, a | dbSNP:79544603 |
| complement(673) | - | g, c | dbSNP:9273947 |
| complement(674) | - | g, c | dbSNP:9273946 |
| complement(677..678) | - | , t | dbSNP:9282122 |
| 678 | + | a, c, g, t | dbSNP:701564 |
| complement(678) | - | t, c | dbSNP:79713081 |
| 678 | + | a, g | dbSNP:78854068 |
| complement(680) | - | , g, c | dbSNP:9273943 |
| complement(681) | - | , g, c | dbSNP:9273942 |
| 682 | + | , a | dbSNP:41548921 |
| 684 | + | a, c | dbSNP:41559620 |
| complement(685) | - | g, a | dbSNP:76063882 |
| complement(685) | - | g, a | dbSNP:75643968 |
| complement(685) | - | g, a | dbSNP:112692669 |
| 685 | + | , a, c, g, t | dbSNP:1049092 |
| 686 | + | a, g | dbSNP:80255621 |
| complement(689) | - | g, a | dbSNP:9273939 |
| complement(691) | - | g, c | dbSNP:9273938 |
| complement(692..693) | - | , gt | dbSNP:9282121 |
| complement(695) | - | g, a | dbSNP:9273937 |
| complement(696) | - | t, c | dbSNP:9273936 |
| complement(697) | - | g, a | dbSNP:9273935 |
| complement(699..700) | - | , a | dbSNP:9282120 |
| complement(707) | - | g, a | dbSNP:9273934 |
| complement(708) | - | t, c | dbSNP:9273933 |
| complement(709) | - | g, c | dbSNP:9273932 |
| complement(711) | - | g, c | dbSNP:9273931 |
| complement(712) | - | g, a | dbSNP:9273930 |
| complement(713..714) | - | , cct | dbSNP:9282119 |
| complement(715) | - | g, c | dbSNP:9273929 |
| complement(716) | - | t, g | dbSNP:9273928 |
| complement(718) | - | t, g | dbSNP:9273927 |
| complement(719) | - | g, a | dbSNP:9273926 |
| complement(720) | - | t, a | dbSNP:9273925 |
| complement(723..724) | - | , a | dbSNP:9282118 |
| 723 | + | a, c, g, t | dbSNP:1130398 |
| complement(723) | - | t, c | dbSNP:80225756 |
| complement(725) | - | g, a | dbSNP:9273923 |
| complement(727) | - | g, a | dbSNP:9273922 |
| complement(728) | - | t, c | dbSNP:9273921 |
| complement(730) | - | g, a | dbSNP:9273920 |
| 732 | + | c, t | dbSNP:1130399 |
| complement(732) | - | g, a | dbSNP:75568288 |
| complement(732) | - | g, a | dbSNP:76322373 |
| complement(734) | - | t, c | dbSNP:9273918 |
| complement(734) | - | t, c | dbSNP:80147466 |
| complement(738) | - | , t | dbSNP:9280008 |
| complement(740) | - | g, a | dbSNP:9273917 |
| complement(741) | - | g, c | dbSNP:9273916 |
| complement(742) | - | g, c | dbSNP:9273915 |
| 743 | + | c, t | dbSNP:63267060 |
| complement(744) | - | t, c | dbSNP:9273667 |
| complement(746) | - | g, c | dbSNP:9273666 |
| complement(747) | - | t, g | dbSNP:9273665 |
| complement(748) | - | t, a | dbSNP:9273664 |
| complement(749) | - | g, c | dbSNP:9273663 |
| complement(751) | - | t, c, a | dbSNP:9273660 |
| complement(759) | - | , at, g, c | dbSNP:9273659 |
| complement(763) | - | , g, c | dbSNP:9273658 |
| complement(766) | - | c, a | dbSNP:9273657 |
| complement(767) | - | t, a | dbSNP:9273656 |
| 768 | + | a, c, g | dbSNP:1130429 |
| complement(771) | - | t, c | dbSNP:9273654 |
| complement(773) | - | t, g | dbSNP:9273653 |
| complement(775) | - | c, a | dbSNP:9273652 |
| complement(776..777) | - | , a | dbSNP:9279976 |
| complement(779) | - | t, c, a | dbSNP:9273651 |
| complement(780..781) | - | , g | dbSNP:9282094 |
| complement(784) | - | g, c, a | dbSNP:9273650 |
| complement(784) | - | g, a | dbSNP:77643116 |
| 785 | + | a, c, g, t | dbSNP:1049163 |
| complement(788..789) | - | , t | dbSNP:9282093 |
| complement(789) | - | c, a | dbSNP:9273647 |
| complement(790) | - | t, g | dbSNP:9273646 |
| complement(791) | - | c, a | dbSNP:9273645 |
| complement(792) | - | c, a | dbSNP:9273644 |
| complement(794) | - | g, a | dbSNP:9273643 |
| complement(798) | - | c, a | dbSNP:9273642 |
| complement(805) | - | g, c | dbSNP:9273641 |
| 808 | + | c, g, t | dbSNP:1130410 |
| complement(811) | - | g, a | dbSNP:9273639 |
| complement(812) | - | t, a | dbSNP:9273638 |
| complement(816) | - | t, a | dbSNP:9273637 |
| 817 | + | c, t | dbSNP:1130430 |
| 817 | + | c, t | dbSNP:35457576 |
| complement(819) | - | , g, c | dbSNP:9273635 |
| complement(820) | - | t, c | dbSNP:9273634 |
| 823 | + | g, t | dbSNP:17412886 |
| complement(823) | - | c, a | dbSNP:77960343 |
| 823 | + | , a, g, t | dbSNP:1130431 |
| complement(826) | - | t, g | dbSNP:9273632 |
| complement(827) | - | g, c | dbSNP:9273631 |
| complement(829) | - | g, a | dbSNP:9273630 |
| complement(832) | - | g, a | dbSNP:112517017 |
| 832 | + | , c, g, t | dbSNP:3210168 |
| complement(834) | - | t, a | dbSNP:9273628 |
| complement(835) | - | t, g | dbSNP:9273627 |
| complement(836) | - | g, c | dbSNP:9273626 |
| 837 | + | a, g | dbSNP:1140342 |
| 837 | + | a, g | dbSNP:34134876 |
| complement(839..840) | - | , tg | dbSNP:9279972 |
| 841 | + | a, c, g | dbSNP:1140343 |
| complement(846) | - | t, c | dbSNP:9273622 |
| complement(847) | - | g, a | dbSNP:9273621 |
| 849 | + | a, c, g | dbSNP:1130432 |
| 849 | + | a, g | dbSNP:17412893 |
| complement(853) | - | t, c | dbSNP:9273618 |
| 859 | + | c, t | dbSNP:1140347 |
| 880 | + | a, g | dbSNP:17416274 |
| complement(880) | - | t, c | dbSNP:74636670 |
| complement(889) | - | t, c, a | dbSNP:9273469 |
| 890 | + | a, g | dbSNP:17416288 |
| complement(890) | - | t, c | dbSNP:78557713 |
| complement(893) | - | g, a | dbSNP:76263361 |
| 893 | + | c, t | dbSNP:17412900 |
| complement(893) | - | g, a | dbSNP:113129258 |
| 905 | + | a, c, g, t | dbSNP:1063345 |
| complement(912) | - | t, c | dbSNP:9273467 |
| complement(914) | - | g, a | dbSNP:9273466 |
| 923 | + | a, g | dbSNP:7656 |
| 925 | + | c, g, t | dbSNP:1063347 |
| complement(943) | - | t, c | dbSNP:41269989 |
| complement(947) | - | g, a | dbSNP:9273463 |
| complement(958) | - | g, a | dbSNP:9273462 |
| 967 | + | , t | dbSNP:3842708 |
| 975 | + | a, g | dbSNP:1063349 |
| complement(996) | - | t, c | dbSNP:113664950 |
| complement(998) | - | t, a | dbSNP:76228204 |
| complement(999) | - | t, c | dbSNP:74785819 |
| 999 | + | a, g | dbSNP:1071639 |
| 1029 | + | c, t | dbSNP:1130420 |
| complement(1030) | - | c, a | dbSNP:9273459 |
| 1031 | + | a, g | dbSNP:3210176 |
| complement(1034..1035) | - | , c | dbSNP:66772188 |
| complement(1035..1036) | - | , c, a | dbSNP:9282076 |
| 1037 | + | a, c, g | dbSNP:1130422 |
| complement(1048) | - | g, a | dbSNP:1770 |
| complement(1051) | - | t, c | dbSNP:9273455 |
| complement(1063) | - | c, a | dbSNP:115749644 |
| complement(1069) | - | g, c | dbSNP:9273453 |
| 1074 | + | a, c, t | dbSNP:1049122 |
| complement(1074) | - | t, a | dbSNP:76918155 |
| complement(1083) | - | t, c | dbSNP:78083269 |
| 1083 | + | a, g | dbSNP:1071641 |
| complement(1086) | - | g, a | dbSNP:1766 |
| complement(1086) | - | g, a | dbSNP:76734826 |
| complement(1086) | - | g, a | dbSNP:78924926 |
| 1087 | + | a, g | dbSNP:1049123 |
| complement(1096) | - | g, a | dbSNP:1764 |
| complement(1096) | - | g, a | dbSNP:117396570 |
| complement(1097) | - | t, c | dbSNP:79173012 |
| complement(1097) | - | t, c | dbSNP:78372297 |
| complement(1104) | - | g, c | dbSNP:79471319 |
| 1108 | + | c, t | dbSNP:1049213 |
| 1118 | + | a, t | dbSNP:1049219 |
| 1118 | + | a, t | dbSNP:16871438 |
| 1129 | + | a, g | dbSNP:1049222 |
| complement(1129) | - | t, c | dbSNP:75420232 |
| complement(1134) | - | g, a | dbSNP:74485399 |
| complement(1134) | - | g, a | dbSNP:76484425 |
| 1134 | + | c, t | dbSNP:1049225 |
| 1167 | + | a, c | dbSNP:1063355 |
| complement(1167) | - | t, g | dbSNP:77119248 |
| 1167 | + | a, c | dbSNP:74466734 |
| 1167 | + | a, c | dbSNP:113823206 |
| 1168 | + | c, t | dbSNP:1049124 |
| 1181 | + | c, t | dbSNP:6689 |
| complement(1181) | - | g, a | dbSNP:77762292 |
| complement(1185..1186) | - | , a | dbSNP:71866696 |
| Gene Symbol | HLA-DQB1 |
| Gene Synonym | CELIAC1; HLA-DQB; IDDM1 |
| Chromosome | 6 |
| Locus Map | 6p21.3 |
| All Transcripts | NM_002123 |
| Title | High frequency of low-risk human leukocyte antigen class II genotypes in latent celiac disease . |
| Author | Schirru,E., Jores,R.D., Cicotto,L., Frau,F., De Virgiliis,S., Rossino,R., Macis,M.D., Lampis,R. and Congia,M. |
| Journal | Hum. Immunol. 72 (2), 179-182 (2011) |
| Title | Genome-wide association study identifies susceptibility loci for IgA nephropathy . |
| Author | Gharavi,A.G., Kiryluk,K., Choi,M., Li,Y., Hou,P., Xie,J., Sanna-Cherchi,S., Men,C.J., Julian,B.A., Wyatt,R.J., Novak,J., He,J.C., Wang,H., Lv,J., Zhu,L., Wang,W., Wang,Z., Yasuno,K., Gunel,M., Mane,S., Umlauf,S., Tikhonova,I., Beerman,I., Savoldi,S., Magistroni,R., Ghiggeri,G.M., Bodria,M., Lugani,F., Ravani,P., Ponticelli,C., Allegri,L., Boscutti,G., Frasca,G., Amore,A., Peruzzi,L., Coppo,R., Izzi,C., Viola,B.F., Prati,E., Salvadori,M., Mignani,R., Gesualdo,L., Bertinetto,F., Mesiano,P., Amoroso,A., Scolari,F., Chen,N., Zhang,H. and Lifton,R.P. |
| Journal | Nat. Genet. 43 (4), 321-327 (2011) |
| Title | The relationship between human leukocyte antigens (HLA) and renal cell carcinoma . |
| Author | Yilmaz,E., Cekmen,A., Akkus,E., Onal,B., Ozalp,A.U., Solok,V., Erdogan,E. and Eren,B. |
| Journal | Bosn J Basic Med Sci 10 (4), 282-286 (2010) |
| Title | Frequency of HLA-DQA1*0501 and DQB1*0201 alleles in patients with coeliac disease, their first-degree relatives and controls in Jordan . |
| Author | El-Akawi,Z.J., Al-Hattab,D.M. and Migdady,M.A. |
| Journal | Ann Trop Paediatr 30 (4), 305-309 (2010) |
| Title | Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset . |
| Author | Khankhanian,P., Gourraud,P.A., Caillier,S.J., Santaniello,A., Hauser,S.L., Baranzini,S.E. and Oksenberg,J.R. |
| Journal | BMC Genomics 11, 626 (2010) |
| Title | Report on the sequence of DQB1*0301 gene in ocular cicatricial pemphigoid patients . |
| Author | Haider,N., Neuman,R., Foster,C.S. and Ahmed,A.R. |
| Journal | Curr. Eye Res. 11 (12), 1233-1238 (1992) |
| Title | Molecular analysis of novel HLA-DR2.DQwl haplotypes in Asian Indians . |
| Author | Singal,D.P., Qiu,X. and Sood,S.K. |
| Journal | Tissue Antigens 40 (2), 104-107 (1992) |
| Title | A rare HLA DQB allele sequenced from patients with systemic lupus erythematosus . |
| Author | Fronek,Z., Timmerman,L.A. and McDevitt,H.O. |
| Journal | Hum. Immunol. 30 (2), 77-84 (1991) |
| Title | Full length beta chain cDNAs of DQw9 and DQw8 molecules encode proteins that differ only at amino acid 57 . |
| Author | Giorda,R., Turco,E. and Trucco,M. |
| Journal | Immunogenetics 33 (5-6), 404-408 (1991) |
| Title | Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA . |
| Author | Bugawan,T.L. and Erlich,H.A. |
| Journal | Immunogenetics 33 (3), 163-170 (1991) |
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