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Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA.


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_004335 Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

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RefSeq Version NM_004335.2, 7262372
Length 983 bp
Structure linear
Update Date 29-APR-2013
Organism Homo sapiens (human)
Definition Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA.
Product bone marrow stromal antigen 2
Comment

Summary: Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008].

RefSeq NP_004326.1
CDS 10..552
Misc Feature(1)70..153
Misc Feature(2)70..153
Misc Feature(3)<217..>456
Translation MASTSYDYCRVPMEDGDKRCKLLLGIGILVLLIIVILGVPLIIFTIKANSEACRDGLRAV MECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKVEELEGEI TTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSSAAAPQLLIVLLGLSALLQ
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Position Chain Variation Link
complement(31)-g, adbSNP:141648094
complement(155)-t, cdbSNP:144978205
complement(169)-g, adbSNP:200950817
complement(213)-t, cdbSNP:11542666
complement(252)-g, adbSNP:34737311
complement(312)-g, adbSNP:139197754
complement(376)-g, adbSNP:150805489
complement(394)-t, cdbSNP:200644366
complement(396)-g, cdbSNP:189347354
complement(415)-t, gdbSNP:201516178
complement(436)-t, gdbSNP:1804402
complement(444)-t, cdbSNP:11542665
complement(445)-c, adbSNP:201005145
complement(469)-g, adbSNP:201381365
complement(501)-t, cdbSNP:143149224
Gene SymbolBST2
Gene SynonymCD317; TETHERIN
Chromosome19
Locus Map19p13.1
All Transcripts
RefSeq Accession Definition Stock Status Price Turnaround time Business Day Select
NM_004335 Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. In-stock $308.00 $259.00 10
Title BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1) .
Author Jones,P.H., Maric,M., Madison,M.N., Maury,W., Roller,R.J. and Okeoma,C.M.
Journal Virology 438 (1), 37-49 (2013)
Title Cell-cell transmission allows human T-lymphotropic virus 1 to circumvent tetherin restriction .
Author Ilinskaya,A., Derse,D., Hill,S., Princler,G. and Heidecker,G.
Journal Virology 436 (1), 201-209 (2013)
Title Association of BST-2 gene variants with HIV disease progression underscores the role of BST-2 in HIV type 1 infection .
Author Laplana,M., Caruz,A., Pineda,J.A., Puig,T. and Fibla,J.
Journal J. Infect. Dis. 207 (3), 411-419 (2013)
Title Stimulation of NF-kappaB activity by the HIV restriction factor BST2 .
Author Tokarev,A., Suarez,M., Kwan,W., Fitzpatrick,K., Singh,R. and Guatelli,J.
Journal J. Virol. 87 (4), 2046-2057 (2013)
Title The size and conservation of a coiled-coil structure in the ectodomain of human BST-2/tetherin is dispensable for inhibition of HIV-1 virion release .
Author Andrew,A.J., Berndsen,C.E., Kao,S. and Strebel,K.
Journal J. Biol. Chem. 287 (53), 44278-44288 (2012)
Title Characterization of antibodies submitted to the B cell section of the 8th Human Leukocyte Differentiation Antigens Workshop by flow cytometry and immunohistochemistry .
Author Vidal-Laliena,M., Romero,X., March,S., Requena,V., Petriz,J. and Engel,P.
Journal Cell. Immunol. 236 (1-2), 6-16 (2005)
Title Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways .
Author Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O., Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H. and Sugano,S.
Journal Oncogene 22 (21), 3307-3318 (2003)
Title Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells .
Author Ohtomo,T., Sugamata,Y., Ozaki,Y., Ono,K., Yoshimura,Y., Kawai,S., Koishihara,Y., Ozaki,S., Kosaka,M., Hirano,T. and Tsuchiya,M.
Journal Biochem. Biophys. Res. Commun. 258 (3), 583-591 (1999)
Title Cloning of a cDNA encoding rat bone marrow stromal cell antigen 1 (BST-1) from the islets of Langerhans .
Author Furuya,Y., Takasawa,S., Yonekura,H., Tanaka,T., Takahara,J. and Okamoto,H.
Journal Gene 165 (2), 329-330 (1995)
Title Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth .
Author Ishikawa,J., Kaisho,T., Tomizawa,H., Lee,B.O., Kobune,Y., Inazawa,J., Oritani,K., Itoh,M., Ochi,T., Ishihara,K. et al.
Journal Genomics 26 (3), 527-534 (1995)


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