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Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA.


Clone ID Definition Vector Stock Status Price *Turnaround time Order
OHu15823 Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. pcDNA3.1+-DYK In-stock $99.00 5-7
OHu15823C Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. Customized vector In-stock $149.00 5-7

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Sequence Information ORF Nucleotide Sequence
Protein sequence
Vector pcDNA3.1+-DYK or customized vector
Clone information Data sheet
Tag on pcDNA3.1+-DYK N terminal DYKDDDK tags
Restriction Sites Hind III- EcoR I
RefSeq Version NM_004335.3, 542133069
Length 543 bp
Structure linear
Update Date 13-APR-2014
Organism Homo sapiens (human)
Definition Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA.
Product bone marrow stromal antigen 2 precursor
Comment

Summary: Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008].

RefSeq NP_004326.1
CDS 82..624
Misc Feature(1)40..42
Misc Feature(2)40..42
Misc Feature(3)142..225
Misc Feature(4)<289..>537
Exon (1)1..366
Gene:BST2
Gene Synonym:CD317; TETHERIN
Exon (2)367..433
Gene:BST2
Gene Synonym:CD317; TETHERIN
Exon (3)434..494
Gene:BST2
Gene Synonym:CD317; TETHERIN
Exon (4)495..639
Gene:BST2
Gene Synonym:CD317; TETHERIN
Exon (5)640..1027
Gene:BST2
Gene Synonym:CD317; TETHERIN
Translation MASTSYDYCRVPMEDGDKRCKLLLGIGILVLLIIVILGVPLIIFTIKANSEACRDGLRAV MECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKVEELEGEI TTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSSAAAPQLLIVLLGLSALLQ
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Position Chain Variation Link
Gene SymbolBST2
Gene SynonymCD317; TETHERIN
Chromosome19
Locus Map19p13.1
All Transcripts
RefSeq Accession Definition Stock Status Price Turnaround time Business Day Select
NM_004335 Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. In-stock $99.00 5-7
Title BST2/CD317 counteracts human coronavirus 229E productive infection by tethering virions at the cell surface .
Author Wang SM, Huang KJ and Wang CT.
Journal Virology 449, 287-296 (2014)
Title CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules .
Author Petris G, Casini A, Sasset L, Cesaratto F, Bestagno M, Cereseto A and Burrone OR.
Journal J. Biol. Chem. 289 (1), 1-12 (2014)
Title Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity .
Author Zenner HL, Mauricio R, Banting G and Crump CM.
Journal J. Virol. 87 (24), 13115-13123 (2013)
Title Tetherin restricts herpes simplex virus 1 and is antagonized by glycoprotein M .
Author Blondeau C, Pelchen-Matthews A, Mlcochova P, Marsh M, Milne RS and Towers GJ.
Journal J. Virol. 87 (24), 13124-13133 (2013)
Title A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release .
Author Sauter D, Hotter D, Engelhart S, Giehler F, Kieser A, Kubisch C and Kirchhoff F.
Journal Retrovirology 10, 85 (2013)
Title Characterization of antibodies submitted to the B cell section of the 8th Human Leukocyte Differentiation Antigens Workshop by flow cytometry and immunohistochemistry .
Author Vidal-Laliena M, Romero X, March S, Requena V, Petriz J and Engel P.
Journal Cell. Immunol. 236 (1-2), 6-16 (2005)
Title Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways .
Author Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H and Sugano S.
Journal Oncogene 22 (21), 3307-3318 (2003)
Title Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells .
Author Ohtomo T, Sugamata Y, Ozaki Y, Ono K, Yoshimura Y, Kawai S, Koishihara Y, Ozaki S, Kosaka M, Hirano T and Tsuchiya M.
Journal Biochem. Biophys. Res. Commun. 258 (3), 583-591 (1999)
Title Cloning of a cDNA encoding rat bone marrow stromal cell antigen 1 (BST-1) from the islets of Langerhans .
Author Furuya Y, Takasawa S, Yonekura H, Tanaka T, Takahara J and Okamoto H.
Journal Gene 165 (2), 329-330 (1995)
Title Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth .
Author Ishikawa J, Kaisho T, Tomizawa H, Lee BO, Kobune Y, Inazawa J, Oritani K, Itoh M, Ochi T and Ishihara K.
Journal Genomics 26 (3), 527-534 (1995)

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