Reviewed (UniProtKB/Swiss-Prot)

  • THAT AND
  • THAT AND

Reviewed (UniProtKB/Swiss-Prot)





Protein Names | ProteinIDs  | Organism | Gene Names  | GeneID | Genome Annotation(Ensembl) |  Protein Sequence | 
General annotation |  References | Order
Protein Names
Recommended name:
 NADH-ubiquinone oxidoreductase chain 4;
Alternative name(s):
Protein IDs
(Accession numbers)
UniProtKB
 A0S0D2
NCBI RefSeq
Organism
Latin Name/
(Common Name)
Sus scrofa (Pig).
Taxonomic Identifier (NCBI)
 9823
Gene Names
 ND4
GeneID
Genome
Annotation (Ensembl)
Protein Sequence
 
SEQUENCE   459 AA;  51929 MW;  E0909A1E0A783521 CRC64;
MLKIIIPTTM LLPMTWMSKH NMIWINATVH SLLISLISLS LLNQLGENSL NFSLTFFSDS
LSAPLLVLTT WLLPLMLMAS QIHLSKETTT RKKLYITMLI LLQLFLIMTF TATELILFYI
LFEATLVPTL IIITRWGNQT ERLNAGLYFL FYTLAGSLPL LVALVYIQNT TGSLNFLIIH
YWSHPLSNSW SNIFMWLACI MAFMVKMPLY GLHLWLPKAH VEAPIAGSMV LAAVLLKLGG
YGMMRITTIL KPLTNYMAYP FLMLSMWGMI MTSSICLRQT DLKSLIPYSS VSHMALVIVA
IMIQTPWSFM GATALMIAHG LTSSMLFCLA NTNYERVHSR TMILARGLQT LLPLMATWWL
MASLTNLALP PSINLIGELF IITASFSWSN ITIILMGMNM MITALYSLYM LIITQRGKYT
HHINNIKPSF TRENALMALH ILPLLLLTLN PKMILGPLY
General annotation
Function
 Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Cofactor
Subunit structure
Subcellular location

Mitochondrion membrane; Multi-pass membrane protein (By similarity).
Tissue specificity
Induction
Domain
Post-translational modification

Involvement in disease

References

  • "Phylogenetic analysis and genetic diversity of the Korean wild boars based on complete mitochondrial DNA sequence.", Cho I.C., Han S.H., Ko M.S., Jeon J.T., Andersson L., Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.,

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Protein Domain Databases
InterPro

IPR010227, NADH_Q_OxRdtase_chainM/4.

IPR000260, NADH_UbQ_OxRdtase_chain4_N.

IPR003918, NADH_UbQ_OxRdtase.

IPR001750, NADH_UbQ/plastoQ_OxRdtase.
Gene3D
PANTHER
Pfam

PF01059, Oxidored_q5_N; 1.

PF00361, Oxidored_q1; 1.
PRINTS

PR01437, NUOXDRDTASE4.
SUPFAM
PROSITE
3D Structure
Database (PDB)
Entry
Method
Resolution (A)
Chain
Positions
PDBsum
Sequence
Annotation
Feature key
Position(s)
Length
Description
Protein-protein
Interaction
Databases
DIP
IntAct
MINT
STRING

A0S0D2
Binary Interactions
With
Entry
#Exp.
IntAct
Enzyme and Pathway Databases
Pathway
Interaction DB
Reactome
Phylogenomic Database
HOVERGEN

HBG093667
InParanoid
OMA
OrthoDB
Proteomics
Database (PRIDE)
Comparative
Toxicogenomics
Database (CTD)
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