Reviewed (UniProtKB/Swiss-Prot)

  • THAT AND
  • THAT AND

Reviewed (UniProtKB/Swiss-Prot)





Protein Names | ProteinIDs  | Organism | Gene Names  | GeneID | Genome Annotation(Ensembl) |  Protein Sequence | 
General annotation |  References | Order
Protein Names
Recommended name:
 Pregnane X receptor;
Alternative name(s):
Protein IDs
(Accession numbers)
UniProtKB
 A5A0Y5
NCBI RefSeq

NP_001118144.1, NM_001124672.1.
Organism
Latin Name/
(Common Name)
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
Taxonomic Identifier (NCBI)
 8022
Gene Names
 ONCMY [GenPool]
GeneID

100136707
Genome
Annotation (Ensembl)
Protein Sequence
 
SEQUENCE   455 AA;  52183 MW;  F0D348B348C1ACDE CRC64;
MSKENLNDWP PSQTSAEEEE EEEDDGEPKV CQVCGDRATG YHFNAMTCEG CKGFFRRAMK
HPTKFCCPRQ GVCVITKNNR RQCQACRLHK CQSIGMLKEL IMSKEAVEKR RSQIRRNRMV
EEPPVLSPQQ EAVIQELFNA HEKTFDITFS HFQFRPIDRD LNPMSVWNQT ASEQSVKQTR
RMDNLSSSYS TSTSTSFSSS SCSLEDEEKE DRSGGKNTVF TTLPDVADLT TNMEEKKEEE
KEKKEDRSDG GKNTVFTTLP HIADLTTYMI QNIINFAKGL PSFRALAIDD QISLLKGAMF
EMMQIRFNMM FNVKTGIWEC GPLTYCMDDA VRAGFQRHLL DPLMRFHYTL RNLQLQEVEY
VLMQAISLFS PDRPGVINHG VIDSLQEKLA IALKVHIDSK RAKPEKHLLY PKILACLTEM
RTMNEEYTKQ VLQIQDIQPG NSFDPLILEV VSKDP
General annotation
Function
Cofactor
Subunit structure
Subcellular location

Tissue specificity
Induction
Domain
Post-translational modification

Involvement in disease

References

  • "Interactions of pharmaceuticals and other xenobiotics on hepatic pregnane X receptor and cytochrome P450 3A signaling pathway in rainbow trout (Oncorhynchus mykiss).", Wassmur B., Grans J., Kling P., Celander M.C., Aquat. Toxicol. 100:91-100(2010)., PubMed:20719396 DOI:10.1016/j.aquatox.2010.07.013

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Protein Domain Databases
InterPro

IPR013088, Znf_NHR/GATA.

IPR008946, Nucl_hormone_rcpt_ligand-bd.

IPR001628, Znf_hrmn_rcpt.

IPR000536, Nucl_hrmn_rcpt_lig-bd_core.

IPR001723, Str_hrmn_rcpt.
Gene3D

G3DSA:1.10.565.10, Nucl_hrmn_rcpt_lig_bd; 2.

G3DSA:3.30.50.10, Znf_NHR/GATA; 1.
PANTHER
Pfam

PF00104, Hormone_recep; 1.

PF00105, zf-C4; 1.
PRINTS

PR00047, STROIDFINGER.

PR00398, STRDHORMONER.
SUPFAM

SSF48508, Str_ncl_receptor; 2.
PROSITE

PS00031, NUCLEAR_REC_DBD_1; 1.

PS51030, NUCLEAR_REC_DBD_2; 1.
3D Structure
Database (PDB)
Entry
Method
Resolution (A)
Chain
Positions
PDBsum
Sequence
Annotation
Feature key
Position(s)
Length
Description
Protein-protein
Interaction
Databases
DIP
IntAct
MINT
STRING
Binary Interactions
With
Entry
#Exp.
IntAct
Enzyme and Pathway Databases
Pathway
Interaction DB
Reactome
Phylogenomic Database
HOVERGEN

HBG108655
InParanoid
OMA
OrthoDB
Proteomics
Database (PRIDE)
Comparative
Toxicogenomics
Database (CTD)

8856
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