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References - Selected Publications
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References - Selected Publications
References
Antibody Engineering
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Jin Q, Ding W, Mulder KM. The TgfΒ Receptor-Interacting Protein Km23-1/Dynlrb1 Plays An Adaptor Role In TgfΒ1 Autoinduction Via Its Association With Ras.
J. Biol. Chem.
2012-7; 287(31): 26453 - 26463
Karin Williams, Ritwik Ghosh, Premkumar Vummidi Giridhar, Guangyu Gu, Thomas Case, Scott M. Belcher, and Susan Kasper Inhibition Of Stathmin1 Accelerates The Metastatic Process.
Cancer Research.
2012-10; 72(20): 5407 - 5417
Nu Zhang, Xinjian Wu, Lixuan Yang, Feizhe Xiao, Heng Zhang, Aidong Zhou, Zhengsong Huang, and Suyun Huang Foxm1 Inhibition Sensitizes Resistant Glioblastoma Cells To Temozolomide By Downregulating The Expression Of Dna-Repair Gene Rad51.
Clin Cancer Res.
2012-11; 18(NULL): 5961 - 5971
Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells Myo1C Facilitates G-Actin Transport To The Leading Edge Of Migrating Endothelial Cells.
J. Cell Biol.
2012-7; 198(1): 47 - 55
Ryan L. Boudreau, Ryan M. Spengler, Ray H. Hylock, Brandyn J. Kusenda, Heather A. Davis, David A. Eichmann, and Beverly L. Davidson Sispotr: A Tool For Designing Highly Specific And Potent Sirnas For Human And Mouse.
Nucleic Acids Res.
2013-1; 10(NULL): 1093
Hu B, Nandhu MS, Sim H, Agudelo-Garcia PA, Saldivar JC, Dolan CE, Mora ME, Nuovo GJ, Cole SE, Viapiano MS. Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.
Cancer Research.
2012-8; NULL(NULL): NULL
Lv XC, Huang ZQ, Zhang W, Rao PF, Ni L. Identification and characterization of filamentous fungi isolated from fermentation starters for Hong Qu glutinous rice wine brewing.
J Gen Appl Microbiol.
2012; 58(1): 33-42
Li ZZ, Tao LL, Zhang J, Zhang HJ, Qu JM. Role of NOD2 in regulating the immune response to Aspergillus fumigatus.
Inflamm Res.
2012-6; NULL(NULL): NULL
Yuan W, Zhang X, Xia X, Sun H. Inhibition Of Infectious Bursal Disease Virus Infection By Artificial Micrornas Targeting Chicken Heat-Shock Protein 90.
J Gen Virol.
2012-4; 93(Pt 4): 876 - 9
Liu XL, Zhang PF, Ding SF, Wang Y, Zhang M, Zhao YX, Ni M, Zhang Y. Local gene silencing of monocyte chemoattractant protein-1 prevents vulnerable plaque disruption in apolipoprotein e-knockout mice.
PLoS One.
2012; 7(3): e33497
Rios AC, Marcelle C, Serralbo O. Gene Loss-Of-Function And Live Imaging In Chick Embryos.
Methods Mol Biol.
2012; 839(NULL): 105-17
Matthias Liniger, Artur Summerfield, Gert Zimmer, Kenneth C. McCullough and Nicolas Ruggli Chicken Cells Sense Influenza A Virus Infection Through Mda5 And Cardif-Signaling Involving Lgp2.
Journal of virology
2011-11; NULL(NULL): NULL
X-X He, Y Chang, F-Y Meng, M-Y Wang, Q-H Xie, F Tang, P-Y Li, Y-H Song and J-S Lin Microrna-375 Targets Aeg-1 In Hepatocellular Carcinoma And Suppresses Liver Cancer Cell Growth In Vitro And In Vivo.
Oncogene.
2012-7; NULL(NULL): NULL
Yiai Tong, Thomas J. Ha, Li Liu, Andrew Nishimoto, Anton Reiner, and Dan Goldowitz. Spatial and Temporal Requirements for huntingtin (
Htt
) in Neuronal Migration and Survival during Brain Development.
J. Neurosci.
2011-10; 31(41): 14794 - 14799
Moumita Datta and Nitai P. Bhattacharyya. Regulation of RE1 Protein Silencing Transcription Factor (REST) Expression by HIP1 Protein Interactor (HIPPI).
J. Biol. Chem.
2011-9; 286(39): 33759 - 33769
Alexander C. Zambon, Andrea Wilderman, Angela Ho, and Paul A. Insel. Increased Expression of the Pro-apoptotic Protein BIM, a Mechanism for cAMP/Protein Kinase A (PKA)-induced Apoptosis of Immature T Cells.
J. Biol. Chem.
2011-9; 286(38): 33260 - 33267
Qing Zhu, Zhengchao Wang, Min Xia, Pin-Lan Li, Benjamin W. Van Tassell, Antonio Abbate, Romesh Dhaduk, and Ningjun Li. Silencing of Hypoxia-Inducible Factor-1α Gene Attenuated Angiotensin II-induced Renal Injury in Sprague-Dawley Rats.
Hypertension.
2011-10; 58(4): 657 - 664
Nicole H. Wilson and Esther T. Stoeckli. Cell type specific, traceable gene silencing for functional gene analysis during vertebrate neural development.
Nucleic Acids Res.
2011-11; 39(20): e133
Zhaoxia Li, Feng Wu, Steven R. Brant, and John H. Kwon. IL-23 Receptor Regulation by Let-7f in Human CD4
+
Memory T Cells.
J. Immunol.
2011-6; 186(11): 6182 - 6190
Wenqiang Pang, Ying Zhang, Shiming Wang, Aiqun Jia, Wei Dong, Chun Cai, Zichun Hua, and Jianfa Zhang. The
mPlrp2
and
mClps
genes are involved in the hydrolysis of retinyl esters in the mouse liver.
J. Lipid Res.
2011-5; 52(5): 934 - 941
Xiao-Qing Dai, Greg Plummer, Marina Casimir, Youhou Kang, Catherine Hajmrle, Herbert Y. Gaisano, Jocelyn E. Manning Fox, and Patrick E. MacDonald. SUMOylation Regulates Insulin Exocytosis Downstream of Secretory Granule Docking in Rodents and Humans.
Diabetes.
2011-3; 60(3): 838 - 847
Wei-Dong Zhao, Wei Liu, Wen-Gang Fang, Kwang Sik Kim, and Yu-Hua Chen. Vascular Endothelial Growth Factor Receptor 1 Contributes to
Escherichia coli
K1 Invasion of Human Brain Microvascular Endothelial Cells through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway.
Infect Immun.
2010-11; 78(11): 4809 - 4816
Bhupinder P. S. Vohra, Yo Sasaki, Bradley R. Miller, Jufang Chang, Aaron DiAntonio, and Jeffrey Milbrandt. Amyloid Precursor Protein Cleavage-Dependent and -Independent Axonal Degeneration Programs Share a Common Nicotinamide Mononucleotide Adenylyltransferase 1-Sensitive Pathway.
J. Neurosci.
2010-10; 30(41): 13729 - 13738
Charalampos Rallis, Sheena M. Pinchin, and David Ish-Horowicz. Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis.
Development.
2010-11; 137(21): 3591 - 3601
Nolan R. Campbell, Catarina C. Fernandes, Andrew W. Halff, and Darwin K. Berg. Endogenous Signaling through α7-Containing Nicotinic Receptors Promotes Maturation and Integration of Adult-Born Neurons in the Hippocampus.
J. Neurosci.
2010-6; 30(26): 8734 - 8744
Xiuxin Liu, Kazue Hashimoto-Torii, Masaaki Torii, Chen Ding, and Pasko Rakic. Gap Junctions/Hemichannels Modulate Interkinetic Nuclear Migration in the Forebrain Precursors.
J. Neurosci.
2010-3; 30(12): 4197 - 4209
Katarzyna Brzeska, Jan Brzeski, Jacquelyn Smith, and Vicki L. Chandler. Transgenic expression of CBBP, a CXC domain protein, establishes paramutation in maize.
PNAS.
2010-3; 107(12): 5516 - 5521
Jianxin Zhu, Ortal Attias, Lamine Aoudjit, Ruihua Jiang, Hiroshi Kawachi, and Tomoko Takano. p21-activated kinases regulate actin remodeling in glomerular podocytes.
Am J Physiol Renal Physiol.
2010-4; 298(NULL): F951 - F961
Przemyslaw Juszczynski, Linfeng Chen, Evan O'Donnell, Jose M. Polo, Stella M. Ranuncolo, Riccardo Dalla-Favera, Ari Melnick, and Margaret A. Shipp. BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt.
Blood.
2009-12; 114(26): 5315 - 5321
Robert A. Neff, III, William G. Conroy, Jeffrey D. Schoellerman, and Darwin K. Berg. Synchronous and Asynchronous Transmitter Release at Nicotinic Synapses Are Differentially Regulated by Postsynaptic PSD-95 Proteins.
J. Neurosci.
2009-12; 29(50): 15770 - 15779
M. Banerjee, M. Datta, P. Majumder, D. Mukhopadhyay, and N. P. Bhattacharyya. Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1.
Nucleic Acids Res.
2010-1; NULL(NULL): NULL
Yongjuan Wang, Huaichang Sun, Pengpeng Shen, Xinyu Zhang, and Xiaoli Xia. Effective inhibition of infectious bursal disease virus replication by recombinant avian adeno-associated virus-delivered microRNAs.
J. Gen. Virol.
2009-6; 90(6): 1417 - 1422
Colin A Flaveny, Iain A Murray, Chris R Chiaro, and Gary H Perdew. Ligand Selectivity and Gene Regulation by the Human Aryl Hydrocarbon Receptor in Transgenic Mice.
Mol. Pharmacol.
2009-6; 75(6): 1412 - 1420
Xin Ge, Horace H Loh, and Ping-Yee Law. mu-Opioid receptor cell surface expression is regulated by its direct interaction with RibophorinI.
Mol. Pharmacol.
2009-6; 75(6): 1307 - 1316
Thomas D. Helton, Takeshi Otsuka, Ming-Chia Lee, Yuanyue Mu, and Michael D. Ehlers. Pruning and loss of excitatory synapses by the parkin ubiquitin ligase.
PNAS.
2008-9; 105(49): 19492 - 19497
P.N. Pushparaj, J.J. Aarthi, J. Manikandan, and S.D. Kumar. siRNA, miRNA, and shRNA:
in vivo
Applications.
J. Dent. Res.
2008-11; 87(11): 992 - 1003
Rosendo Estrada, Qun Zeng, Hongwei Lu, Harshini Sarojini, Jen-Fu Lee, Steven P. Mathis, Teresa Sanchez, Eugenia Wang, Christopher D. Kontos, Chen-Yon Lin, Timothy Hla, Bodduluri Haribabu, and Menq-Jer Lee. Up-regulating sphingosine-1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.
J. Biol. Chem.
2008-10; 283(44): 30363 - 30375
Xiuxin Liu, Kazue Hashimoto-Torii, Masaaki Torii, Tarik F. Haydar, and Pasko Rakic. The role of ATP signaling in the migration of intermediate neuronal progenitors to the neocortical subventricular zone.
PNAS.
2008-8; 105(33): 11802 - 11807
Sarah Hummasti and Peter Tontonoz. HRASLS3 is a PPARγ-selective target gene that promotes adipocyte differentiation.
J. Lipid Res.
2008-12; 49(NULL): 2535 - 2544
Sailesh Surapureddi, Ritu Rana, Janardan K Reddy, and Joyce A Goldstein. Nuclear Receptor Coactivator 6 Mediates the Synergistic Activation of Human Cytochrome P-450 2C9 by the Constitutive Androstane Receptor and Hepatic Nuclear Factor-4α.
Mol. Pharmacol.
2008-9; 74(3): 913 - 923
KangAe Lee, Jeremy D. Lynd, Sandra O'Reilly, Matti Kiupel, J. Justin McCormick, and John J. LaPres. The Biphasic Role of the Hypoxia-Inducible Factor Prolyl-4-Hydroxylase, PHD2, in Modulating Tumor-Forming Potential.
Mol. Cancer Res.
2008-5; 6(5): 829 - 842
Kenjiro Sakaki, Jun Wu, and Randal J. Kaufman. Protein kinase C-theta is required for autophagy in response to stress in the endoplasmic reticulum.
J. Biol. Chem.
2008-5; 283(22): 15370 - 15380
Kristi A. Hohenstein, April D. Pyle, Jing Yi Chern, Leslie F. Lock, and Peter J. Donovan. Nucleofection Mediates High-efficiency Stable Gene Knockdown and Transgene Expression in Human Embryonic Stem Cells.
Stem Cells.
2008-6; 26(6): 1436 - 1443
Young Mook Lee, Seong H. Park, Dong-Ik Shin, Jee-Yeon Hwang, BoKyung Park, Yun-Jong Park, Tae H. Lee, Ho Z. Chae, Byung K. Jin, Tae H. Oh, and Young J. Oh. Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson's disease.
J. Biol. Chem.
2008-4; 283(15): 9986 - 9998
Xing Guo, Alejandro Ramirez, David S. Waddell, Zhizhong Li, Xuedong Liu, and Xiao-Fan Wang. Axin and GSK3-β control Smad3 protein stability and modulate TGF-β signaling.
Genes & Dev.
2008-1; 22(1): 106 - 120
ZHAOHONG YIN, yiai tong, haiqing zhu, and Mitchell A Watsky. ClC-3 is required for LPA-activated Cl
-
current activity and Fibroblast to Myofibroblast Differentiation.
Am. J. Physiol Cell Physiol.
2008-2; 294(2): C535 - C542
Michael Papetti and Arthur I. Skoultchi. Reprogramming Leukemia Cells to Terminal Differentiation and Growth Arrest by RNA Interference of PU.1.
Mol. Cancer Res.
2007-10; 5(NULL): 1053 - 1062
Wang L, Zhang ZG, Gregg SR, Zhang RL, Jiao Z, Letourneau Y, Liu X, Feng Y, Gerwien J, Torup L, Leist M, Noguchi CT, Chen ZY, Chopp M. The sonic hedgehog pathway mediates carbamylated EPO enhanced proliferation and differentiation of adult neural progenitor cells.
J. Biol. Chem.
2007-11; 282(44): 32462 - 32470
Ramakrishna Kommagani, Vandana Payal, and Madhavi P. Kadakia. Differential regulation of vitamin D receptor by the p53 family: p73-dependent Induction of VDR upon DNA damage.
J. Biol. Chem.
2007-10; 282(NULL): 29847 - 29854
Abouhamed M, Wolff NA, Lee WK, Smith CP, Thevenod F. Knockdown of endosomal/lysosomal divalent metal transporter 1 by RNA interference prevents cadmium-metallothionein-1 cytotoxicity in renal proximal tubule cells.
Am J Physiol Renal Physiol.
2007-9; 293(NULL): F705 - F712
Lin JH, Tsai CH, Chu JS, Chen JY, Takada K, Shew JY. Dysregulation of HER2/HER3 signaling axis in Epstein-Barr virus-infected breast carcinoma cells.
J. Virol.
2007-6; 81(11): 5705-5713
Devoogdt N, Revets H, Kindt A, Liu YQ, De Baetselier P, Ghassabeh GH. The Tumor-Promoting Effect of TNF-{alpha} Involves the Induction of Secretory Leukocyte Protease Inhibitor.
J. Immunol.
2006-12; 177(11): 8046-8052
Amanai M, Shoji S, Yoshida N, Brahmajosyula M, Perry AC. Injection of Mammalian Metaphase II Oocytes with Short Interfering RNAs to Dissect Meiotic and Early Mitotic Events.
Biol Reprod.
2006-8; NULL(NULL): NULL
Lee JF, Zeng Q, Ozaki H, Wang L, Hand AR, Hla T, Wang E, Lee MJ. Dual roles of tight junction associated protein, zonula occludens-1, in sphingosine-1-phosphate mediated endothelial chemotaxis and barrier integrity.
J. Biol. Chem.
2006-9; NULL(NULL): NULL
Shafiei M, Rockey DC. The role of integrin linked kinase in liver wound healing.
J. Biol. Chem.
2006-8; 281(34): 24863-24872
Li LX, Macdonald PE, Ahn DS, Oudit GY, Backx PH, Brubaker PL. Role of phosphatidylinositol 3-kinaseγ (PI3-Kγ) in the beta-cell: Interactions with glucagon-like peptide-1.
Endocrinology.
2006-7; 147(7): 3318-3325
Jianqing Ding, Elizabeth Allen, Wei Wang, Angela Valle, Chengbiao Wu, Timothy Nardine, Bianxiao Cui, Jing Yi, Anne Taylor, Noo Li Jeon, Steven Chu, Yuen So, Hannes Vogel, Ravi Tolwani, William Mobley, and Yanmin Yang. Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport.
Hum Mol Genet.
2006-5; 15(NULL): 1451-1463
Dileep Varma, Denis L. Dujardin, Stephanie A. Stehman, and Richard B. Vallee. Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function.
J. Cell Biol.
2006-2; 172(5): 655 - 662
Federici M, Hribal ML, Menghini R, Kanno H, Marchetti V, Porzio O, Sunnarborg SW, Rizza S, Serino M, Cunsolo V, Lauro D, Mauriello A, Smookler DS, Sbraccia P, Sesti G, Lee DC, Khokha R, Accili D, Lauro R. Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-α.
J. Clin. Invest.
2005-12; 115(12): 3494-3505
Ying Tian,Sheri E Kelemen,and Michael V Autieri. Inhibition of AIF-1 Expression by Constitutive siRNA Expression Reduces Macrophage Migration, Proliferation and Signal Transduction initiated by Atherogenic Stimuli.
Am. J. Physiol Cell Physiol.
2006-4; 290(4): C1083-C1091
Wenbo Zhou and Curt R.Freed. DJ-1 upregulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity.
J. Biol. Chem.
2005-12; 280(52): 43150-43158
Pedro J. Real, Adalberto Benito, Jorge Cuevas, Maria T. Berciano, Anade Juan, Paul Coffer, Javier Gomez-Roman, Miguel Lafarga, Jose M,Lopez-Vega, and Jose L. Fernandez-Luna. Blockade of Epidermal Growth Factor Receptors Chemosensitizes Breast Cancer Cells through Up-Regulation of Bnip3L.
Cancer Research.
2005-9; 65(18): 8151-8157
Chen Y, Chen H, Hoffmann A, Cool DR, Diz DI, Chappell MC, Chen A, Morris M. Adenovirus-Mediated Small-Interference RNA for In Vivo Silencing of Angiotensin AT
1a
Receptors in Mouse Brain.
Hypertension.
2006-2; 47(NULL): 230-237
Nihal Kaplan-Albuquerque, Vicki Van Putten, Mary C. Weiser-Evans, and Raphael A. Nemenoff. Depletion of Serum Response Factor by RNA Interference Mimics the Mitogenic Effects of Platelet Derived Growth Factor-BB in Vascular Smooth Muscle Cells.
Circ. Res.
2005-9; 97(5): 427-433
Ian G. Mills, Luke Gaughan, Craig Robson, Theodora Ross, Stuart McCracken, John Kelly, and David E. Neal. Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors.
J. Cell Biol.
2005-7; 170(2): 191-200
Punita Dhawan, Amar B. Singh, Natasha G. Deane, YiRan No, Sheng-Ru Shiou, Carl Schmidt, John Neff, M. Kay Washington, and R. Daniel Beauchamp. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer.
J. Clin. Invest.
2005-7; 115(7): 1765-1776
Ping Gao, Ronald L Wange, Ning Zhang, Joost J Oppenheim, and O. M.Zack Howard. Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.
Blood.
2005-10; 106(8): 2619-2626
Maeda Y, Fukushima K, Nishizaki K, Smith RJ. In vitro and in vivo suppression of GJB2 expression by RNA interference.
Hum Mol Genet.
2005-6; 14(12): 1641-1650
Zhu T, Starling-Emerald B, Zhang X, Lee KO, Gluckman PD, Mertani HC, Lobie PE. Oncogenic transformation of human mammary epithelial cells by autocrine human growth hormone.
Cancer Research.
2005-1; 65(1): 317-324
Yau TO, Chan CY, Chan KL, Lee MF, Wong CM, Fan ST, Ng IO. HDPR1, a novel inhibitor of the WNT/b-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylationmediated gene silencing.
Oncogene.
2005-2; 24(9): 1607-1614
Marilee J. WICK, Stacy BLAINE, Vicki VAN PUTTEN, Milene SAAVEDRA and Raphael A. NEMENOFF. Lung Kruppel-like factor (LKLF) is a transcriptional activator of the cytosolic phospholipase A
2
α promoter.
Biochemical. J.
2005-4; 387(1): 239-246
Qing Shao, Hongling Wang, Elizabeth McLachlan, Gregory I.L. Veitch, and Dale W. Laird. Down-regulation of Cx43 by Retroviral Delivery of Small Interfering RNA Promotes an Aggressive Breast Cancer Cell Phenotype.
Cancer Research.
2005-4; 65(7): 2705-2711
Yao Chang, Shih-Shin Chang, Heng-Huan Lee, Shin-Lian Doong, Kenzo Takada, and Ching-Hwa Tsai. Inhibition of the EpsteinBarr virus lytic cycle by Zta-targeted RNA interference.
J. Gen. Virol.
2004-6; 85(6): 1371-1379
PCR and Cloning
Faye M. Drawnel, Dagmar Wachten, Jeffery D. Molkentin, Marjorie Maillet, Jan Magnus Aronsen, Fredrik Swift, Ivar Sjaastad, Ning Liu, Daniele Catalucci, Katsuhiko Mikoshiba, Chihiro Hisatsune, Hanneke Okkenhaug, Simon R. Andrews, Martin D. Bootman Mutual Antagonism Between Ip3Rii And Mirna-133A Regulates Calcium Signals And Cardiac Hypertrophy.
J. Cell Biol.
2013-2; NULL(NULL): NULL
Adikaram CP, Perera J, Wijesundera SS. Geographical Profile Of Rpob Gene Mutations In Rifampicin Resistant Mycobacterium Tuberculosis Isolates In Sri Lanka.
Microbial Drug Resistance.
2013-2; 18(5): 525-30
Naz S, Ranganathan P, Bodapati P, Shastry AH, Mishra LN, Kondaiah P. Regulation Of S100A2 Expression By Transforming Growth Factor-Beta Induced Mek/Erk Signaling And Its Role In Cell Migration/Invasion.
Biochemical Journal.
2012-7; 447(1): 81-91
Dhar A, Prigozhin M, Gelman H, Gruebele M. Studying IDP Stability and Dynamics by Fast Relaxation Imaging in Living Cells.
Methods Mol Biol.
2012-9; 895(NULL): 101 - 11
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JA Gantz, NJ Palpant, RE Welikson, SD Hauschka Targeted Genomic Integration Of A Selectable Floxed Dual Fluorescence Reporter In Human Embryonic Stem Cells.
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ND Lamb-Palmer, M Singh, JP Dalton, J Singh Prokaryotic Expression And Purification Of Soluble Maize Ac Transposase.
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Jan Terje Andersen, Stian Foss, Vania E. Kenanova, Tove Olafsen, Ingvild S. Leikfoss, Derry C. Roopenian, Anna M. Wu, and Inger Sandlie Anti-Carcinoembryonic Antigen Single-Chain Variable Fragment Antibody Variants Bind Mouse And Human Neonatal Fc Receptor With Different Affinities That Reveal Distinct Cross-Species Differences In Serum Half-Life.
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Dongping Wang, Jun Myoung Yu, Leland S. Pierson, III, and Elizabeth A. Pierson Differential Regulation Of Phenazine Biosynthesis By Rpea And Rpeb In Pseudomonas Chlororaphis 30-84.
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Jenkins DP, Strøbæk D, Hougaard C, Jensen ML, Hummel R, Sørensen US, Christophersen P, Wulff H. Negative Gating Modulation by (R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) Depends on Residues in the Inner Pore Vestibule: Pharmacological Evidence of Deep-Pore Gating of K
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Mol. Pharmacol.
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Yingfeng Zheng, Zhujun Ao, Binchen Wang, Kallesh Danappa Jayappa, and Xiaojian Yao. Host Protein Ku70 Binds and Protects HIV-1 Integrase from Proteasomal Degradation and Is Required for HIV Replication.
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Xianxuan Zhou, Kasemsiri Chandarajoti, Truong Quang Pham, Renpeng Liu, and Jian Liu. Expression of heparan sulfate sulfotransferases in
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Dominique Chu, David J. Barnes, and Tobias von der Haar. The role of tRNA and ribosome competition in coupling the expression of different mRNAs in
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Lesley-Ann Giddings, David K. Liscombe, John P. Hamilton, Kevin L. Childs, Dean DellaPenna, C. Robin Buell, and Sarah E. O'Connor. A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in
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Yi Shi, Doug W. Chan, Sung Yun Jung, Anna Malovannaya, Yi Wang, and Jun Qin. A Data Set of Human Endogenous Protein Ubiquitination Sites.
Mol. Cell. Proteomics.
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Andrew E. Firth, Norma M. Wills, Raymond F. Gesteland, and John F. Atkins. Stimulation of stop codon readthrough: frequent presence of an extended 3' RNA structural element.
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Alex C. Keene, Esteban O. Mazzoni, Jamie Zhen, Meg A. Younger, Satoko Yamaguchi, Justin Blau, Claude Desplan, and Simon G. Sprecher. Distinct Visual Pathways Mediate
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Hisatsugu Koshimizu, Niamh X. Cawley, Taeyoon Kim, Alfred L. Yergey, and Y. Peng Loh. Serpinin: A Novel Chromogranin A-Derived, Secreted Peptide Up-Regulates Protease Nexin-1 Expression and Granule Biogenesis in Endocrine Cells.
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Erinna F. Lee, Oliver B. Clarke, Marco Evangelista, Zhiping Feng, Terence P. Speed, Elissaveta B. Tchoubrieva, Andreas Strasser, Bernd H. Kalinna, Peter M. Colman, and W. Douglas Fairlie. From the Cover: Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes.
PNAS.
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Xinyao Liu, Sarah Fallon, Jie Sheng, and Roy Curtiss, III. CO2-limitation-inducible Green Recovery of fatty acids from cyanobacterial biomass.
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Xinyao Liu, Jie Sheng, and Roy Curtiss III. Fatty acid production in genetically modified cyanobacteria.
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John P. Bannister, Candice M. Thomas-Gatewood, Zachary P. Neeb, Adebowale Adebiyi, Xiaoyang Cheng, and Jonathan H. Jaggar. Ca
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Adrienne Law and Martin J. Boulanger. Defining a Structural and Kinetic Rationale for Paralogous Copies of Phenylacetate-CoA Ligases from the Cystic Fibrosis Pathogen Burkholderia cenocepacia J2315.
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Sam Ogwang, Hoa T. Nguyen, Marissa Sherman, Saralee Bajaksouzian, Michael R. Jacobs, W. Henry Boom, Guo-Fang Zhang, and Liem Nguyen. Bacterial Conversion of Folinic Acid Is Required for Antifolate Resistance.
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Tao Cai, Xiang Chen, Rennian Wang, Huan Xu, Yuhui You, Tao Zhang, Michael S. Lan, and Abner L. Notkins. Expression of Insulinoma-Associated 2 (INSM2) in Pancreatic Islet Cells Is Regulated by the Transcription Factors Ngn3 and NeuroD1.
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Catherine E. Winbanks, Bo Wang, Claudia Beyer, Phillip Koh, Lloyd White, Phillip Kantharidis, and Paul Gregorevic. TGF-β Regulates miR-206 and miR-29 to Control Myogenic Differentiation through Regulation of HDAC4.
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M. Gordon Joyce, Paul Tran, Marina A. Zhuravleva, Jessica Jaw, Marco Colonna, and Peter D. Sun. Crystal structure of human natural cytotoxicity receptor NKp30 and identification of its ligand binding site.
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Habchi J, Blangy S, Mamelli L, Jensen MR, Blackledge M, Darbon H, Oglesbee M, Shu Y, Longhi S. Characterization of the Interactions between the Nucleoprotein and the Phosphoprotein of
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Liger D, Mora L, Lazar N, Figaro S, Henri J, Scrima N, Buckingham RH, van Tilbeurgh H, Heurgué-Hamard V, Graille M. Mechanism of activation of methyltransferases involved in translation by the Trm112 ′hub′ protein.
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Delphine Gogendeau, Ilse Hurbain, Graca Raposo, Jean Cohen, France Koll, and Renata Basto. Sas-4 proteins are required during basal body duplication in
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Hojun Li, Nirav Malani, Shari R. Hamilton, Alexander Schlachterman, Giulio Bussadori, Shyrie E. Edmonson, Rachel Shah, Valder R. Arruda, Federico Mingozzi, J. Fraser Wright, Frederic D. Bushman, and Katherine A. High. Assessing the potential for AAV vector genotoxicity in a murine model.
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Amanda K. Welch, Caleb J. Bostwick, and Brian D. Cain. Manipulations in the Peripheral Stalk of the
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Jun-Rong Wei, Vidhya Krishnamoorthy, Kenan Murphy, Jee-Hyun Kim, Dirk Schnappinger, Tom Alber, Christopher M. Sassetti, Kyu Y. Rhee, and Eric J. Rubin. Depletion of antibiotic targets has widely varying effects on growth.
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Brenda J Leckie and Andrew R Bottrill. A specific binding site for the prorenin propart peptide Arg
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Benedikt B. Kaufer, Keith W. Jarosinski, and Nikolaus Osterrieder. Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation.
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Michaela Leroch, Dennis Mernke, Dieter Koppenhoefer, Prisca Schneider, Andreas Mosbach, Gunther Doehlemann, and Matthias Hahn. Living Colors in the Gray Mold Pathogen Botrytis cinerea: Codon-Optimized Genes Encoding Green Fluorescent Protein and mCherry, Which Exhibit Bright Fluorescence.
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Gudrun R. Stranzl, Eugenio Santelli, Laurie A. Bankston, Chandra La Clair, Andrey Bobkov, Robert Schwarzenbacher, Adam Godzik, Marta Perego, Marcin Grynberg, and Robert C. Liddington. Structural Insights into Inhibition of Bacillus anthracis Sporulation by a Novel Class of Non-heme Globin Sensor Domains.
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E Gandjbakhch, P Charron, V Fressart, G Lorin de la Grandmaison, F Simon, F Gary, A Vite, B Hainque, F Hidden-Lucet, M Komajda, and E Villard. Plakophilin 2A is the dominant isoform in human heart tissue: consequences for the genetic screening of arrhythmogenic right ventricular cardiomyopathy.
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G Levy and G Degani. Evidence of a reproduction-related function for pituitary adenylate cyclase-activating polypeptide-related peptide in an Anabantidae fish.
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Chia Lin Chang, James J. Cai, Po Jen Cheng, Ho Yen Chueh, and Sheau Yu Teddy Hsu. Identification of Metabolic Modifiers That Underlie Phenotypic Variations in Energy-Balance Regulation.
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David M. Mburu, Mary W. Ndung'u, Nguya K. Maniania, and Ahmed Hassanali. Comparison of volatile blends and gene sequences of two isolates of
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De Masi F, Grove CA, Vedenko A, Alibés A, Gisselbrecht SS, Serrano L, Bulyk ML, Walhout AJ. Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants.
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Ziad J. Sahab, Michael D. Hall, You Me Sung, Sivanesan Dakshanamurthy, Yun Ji, Deepak Kumar, and Stephen W. Byers. Tumor Suppressor RARRES1 Interacts with Cytoplasmic Carboxypeptidase AGBL2 to Regulate the α-Tubulin Tyrosination Cycle.
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Robert P. de Vries, Erik de Vries, Karen S. Moore, Alan Rigter, Peter J. M. Rottier, and Cornelis A. M. de Haan. Only Two Residues Are Responsible for the Dramatic Difference in Receptor Binding between Swine and New Pandemic H1 Hemagglutinin.
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Atsushi Ogawa. Rational design of artificial riboswitches based on ligand-dependent modulation of internal ribosome entry in wheat germ extract and their applications as label-free biosensors.
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Emiko Suzuki and Manabu Nakayama. VCre/VloxP and SCre/SloxP: new site-specific recombination systems for genome engineering.
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Steven D. Carson, Nora M. Chapman, Susan Hafenstein, and Steven Tracy. Variations of Coxsackievirus B3 Capsid Primary Structure, Ligands, and Stability Are Selected for in a Coxsackievirus and Adenovirus Receptor-Limited Environment.
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Mouhamed S. Awayda, Karen L. Awayda, Oleh Pochynyuk, Vladislav Bugaj, James D. Stockand, and Rudy M. Ortiz. Acute Cholesterol-induced Anti-natriuretic Effects: ROLE OF EPITHELIAL Na
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Xiaodong Tan, Jason L. Pecka, Jie Tang, Oseremen E. Okoruwa, Qian Zhang, Kirk W. Beisel, and David Z. Z. He. From Zebrafish to Mammal: Functional Evolution of Prestin, the Motor Protein of Cochlear Outer Hair Cells.
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Jennifer C. Pai, Jeffrey A. Culver, Jason E. Drury, Rakesh S. Motani, Raquel L. Lieberman, and Jennifer A. Maynard. Conversion of scFv peptide-binding specificity for crystal chaperone development.
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Paul Smith, Pravin A. Nair, Ushati Das, Hui Zhu, and Stewart Shuman. Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily.
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Narayan V, Pion E, Landré V, Müller P, Ball KL. Docking-dependent Ubiquitination of the Interferon Regulatory Factor-1 Tumor Suppressor Protein by the Ubiquitin Ligase CHIP.
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Tavares S, Grotkjær T, Obsen T, Haslam RP, Napier JA, Gunnarsson N. Metabolic Engineering of Saccharomyces cerevisiae for Production of Eicosapentaenoic Acid, Using a Novel Δ5-Desaturase from Paramecium tetraurelia.
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Yuko Yamamoto, Takaaki Hirai, Eiji Yamamoto, Mayuko Kawamura, Tomomi Sato, Hidemi Kitano, Makoto Matsuoka, and Miyako Ueguchi-Tanaka. A Rice gid1 Suppressor Mutant Reveals That Gibberellin Is Not Always Required for Interaction between Its Receptor, GID1, and DELLA Proteins.
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Gordon G. Simpson, Rebecca E. Laurie, Paul P. Dijkwel, Victor Quesada, Peter A. Stockwell, Caroline Dean, and Richard C. Macknight. Noncanonical Translation Initiation of the
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Xiaowang Qu, Xiaoben Pan, Jessica Weidner, Wenquan Yu, Dominic Alonzi, Xiaodong Xu, Terry Butters, Timothy Block, Ju-Tao Guo, and Jinhong Chang. Inhibitors of Endoplasmic Reticulum {alpha}-Glucosidases Potently Suppress Hepatitis C Virus Virion Assembly and Release.
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Ryan Rampersaud, Paul J. Planet, Tara M. Randis, Ritwij Kulkarni, Jorge L. Aguilar, Robert I. Lehrer, and Adam J. Ratner. Inerolysin, a Cholesterol-Dependent Cytolysin Produced by
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Jennifer J. Paynter, Isabelle Andres-Enguix, Philip W. Fowler, Stephen Tottey, Wayland Cheng, Decha Enkvetchakul, Vassiliy N. Bavro, Yoshio Kusakabe, Mark S. P. Sansom, Nigel J. Robinson, Colin G. Nichols, and Stephen J. Tucker. Functional Complementation and Genetic Deletion Studies of KirBac Channels: ACTIVATORY MUTATIONS HIGHLIGHT GATING-SENSITIVE DOMAINS.
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Jolanta Grembecka, Amalia M. Belcher, Thomas Hartley, and Tomasz Cierpicki. Molecular Basis of the Mixed Lineage Leukemia-Menin Interaction: IMPLICATIONS FOR TARGETING MIXED LINEAGE LEUKEMIAS.
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Morbitzer R, Römer P, Boch J, Lahaye T. Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors.
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David H. Aggen, Adam S. Chervin, Francis K. Insaidoo, Kurt H. Piepenbrink, Brian M. Baker, and David M. Kranz. Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors.
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Yanjie Lu, Ying Zhang, Ning Wang, Zhenwei Pan, Xu Gao, Fengmin Zhang, Yong Zhang, Hongli Shan, Xiaobin Luo, Yunlong Bai, Lihua Sun, Wuqi Song, Chaoqian Xu, Zhiguo Wang, and Baofeng Yang. MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation.
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Matthew Burrell, Colin C. Hanfrey, Ewan J. Murray, Nicola R. Stanley-Wall, and Anthony J. Michael. Evolution and Multiplicity of Arginine Decarboxylases in Polyamine Biosynthesis and Essential Role in
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Bing Yao, Songqing Li, Hyun Min Jung, Shang L. Lian, Grant X. Abadal, Frank Han, Marvin J. Fritzler, and Edward K. L. Chan. Divergent GW182 functional domains in the regulation of translational silencing.
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Yen Pham, Brian Kuhlman, Glenn L. Butterfoss, Hao Hu, Violetta Weinreb, and Charles W. Carter, Jr. Tryptophanyl-tRNA Synthetase Urzyme: A MODEL TO RECAPITULATE MOLECULAR EVOLUTION AND INVESTIGATE INTRAMOLECULAR COMPLEMENTATION.
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Whasil Lee, Xiancheng Zeng, Huan-Xiang Zhou, Vann Bennett, Weitao Yang, and Piotr E. Marszalek. Full Reconstruction of a Vectorial Protein Folding Pathway by Atomic Force Microscopy and Molecular Dynamics Simulations.
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Eun-Jeong Lee and Peter Facchini. Norcoclaurine Synthase Is a Member of the Pathogenesis-Related 10/Bet v1 Protein Family.
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Farideh Ghomashchi, Gajendra S. Naika, James G. Bollinger, Ahmed Aloulou, Matthias Lehr, Christina C. Leslie, and Michael H. Gelb. Interfacial Kinetic and Binding Properties of Mammalian Group IVB Phospholipase A
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Mei Liu, Vidya C. Nadar, Frank Kozielski, Marta Kozlowska, Wenqian Yu, and Peter W. Baas. Kinesin-12, a Mitotic Microtubule-Associated Motor Protein, Impacts Axonal Growth, Navigation, and Branching.
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David S. Gogerty and Thomas A. Bobik. Formation of Isobutene from 3-Hydroxy-3-Methylbutyrate by Diphosphomevalonate Decarboxylase.
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Elizabeth Stansell, Kevin Canis, Stuart M. Haslam, Anne Dell, and Ronald C. Desrosiers. Simian Immunodeficiency Virus from the Sooty Mangabey and Rhesus Macaque Is Modified with O-Linked Carbohydrate.
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Steven M. Damo, Aaron H. Phillips, Anisa L. Young, Sheng Li, Virgil L. Woods, Jr, and David E. Wemmer. Probing the Conformation of a Prion Protein Fibril with Hydrogen Exchange.
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Sebastian Schornack, Mireille van Damme, Tolga O. Bozkurt, Liliana M. Cano, Matthew Smoker, Marco Thines, Elodie Gaulin, Sophien Kamoun, and Edgar Huitema. Ancient class of translocated oomycete effectors targets the host nucleus.
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Justin Yamada, Joshua L. Phillips, Samir Patel, Gabriel Goldfien, Alison Calestagne-Morelli, Hans Huang, Ryan Reza, Justin Acheson, Viswanathan V. Krishnan, Shawn Newsam, Ajay Gopinathan, Edmond Y. Lau, Michael E. Colvin, Vladimir N. Uversky, and Michael F. Rexach. A Bimodal Distribution of Two Distinct Categories of Intrinsically Disordered Structures with Separate Functions in FG Nucleoporins.
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de Vega M, Lázaro JM, Mencía M, Blanco L, Salas M. Improvement of ψ29 DNA polymerase amplification performance by fusion of DNA binding motifs.
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Bin Deng, Sudharsan Parthasarathy, WenFang Wang, Brian R. Gibney, Kevin P. Battaile, Scott Lovell, David R. Benson, and Hao Zhu. Study of the Individual Cytochrome b5 and Cytochrome b5 Reductase Domains of Ncb5or Reveals a Unique Heme Pocket and a Possible Role of the CS Domain.
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Michael H. Norris, Yun Kang, Bruce Wilcox, and Tung T. Hoang. Stable, Site-Specific Fluorescent Tagging Constructs Optimized for
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Simone C. Wiesler and Robert O. J. Weinzierl. The linker domain of basal transcription factor TFIIB controls distinct recruitment and transcription stimulation functions.
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Kantola K, Sadeghi M, Antikainen J, Kirveskari J, Delwart E, Hedman K, Söderlund-Venermo M. Real-Time Quantitative PCR Detection of Four Human Bocaviruses.
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Mookkan Prabakaran, Fang He, Tao Meng, Selvaraj Madhan, Tan Yunrui, Qiang Jia, and Jimmy Kwang. Neutralizing Epitopes of Influenza Virus Hemagglutinin: Target for the Development of a Universal Vaccine against H5N1 Lineages.
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Perales-Clemente E, Fernández-Silva P, Acín-Pérez R, Pérez-Martos A, Enríquez JA. Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?
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Joan A. Geoghegan, Rebecca M. Corrigan, Dominika T. Gruszka, Pietro Speziale, James P. O'Gara, Jennifer R. Potts, and Timothy J. Foster. Role of Surface Protein SasG in Biofilm Formation by
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Benet M, Lahoz A, Guzmán C, Castell JV, Jover R. CCAAT/Enhancer-binding Protein α (C/EBPα) and Hepatocyte Nuclear Factor 4α (HNF4α) Synergistically Cooperate with Constitutive Androstane Receptor to Transactivate the Human Cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model.
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Elena K. Petutschnig, Alexandra M. E. Jones, Liliya Serazetdinova, Ulrike Lipka, and Volker Lipka. The Lysin Motif Receptor-like Kinase (LysM-RLK) CERK1 Is a Major Chitin-binding Protein in Arabidopsis thaliana and Subject to Chitin-induced Phosphorylation.
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David J. Gonzalez, Shaun W. Lee, Mary E. Hensler, Andrew L. Markley, Samira Dahesh, Douglas A. Mitchell, Nuno Bandeira, Victor Nizet, Jack E. Dixon, and Pieter C. Dorrestein. Clostridiolysin S, a Post-translationally Modified Biotoxin from Clostridium botulinum.
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Jimena Castillo Bennett, Carlos M. Roggero, Franco E. Mancifesta, and Luis S. Mayorga. Calcineurin-mediated Dephosphorylation of Synaptotagmin VI Is Necessary for Acrosomal Exocytosis.
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Michael Huber, Khoa M. Le, Katie J. Doores, Zara Fulton, Robyn L. Stanfield, Ian A. Wilson, and Dennis R. Burton. Very Few Substitutions in a Germ Line Antibody Are Required To Initiate Significant Domain Exchange.
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Oliver Grimm and Eric Wieschaus. The Bicoid gradient is shaped independently of nuclei.
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Wilkie S, Burbridge SE, Chiapero-Stanke L, Pereira AC, Cleary S, van der Stegen SJ, Spicer JF, Davies DM, Maher J. Selective Expansion of Chimeric Antigen Receptor-targeted T-cells with Potent Effector Function using Interleukin-4.
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Brett C. DiNatale, Jennifer C. Schroeder, Lauren J. Francey, Ann Kusnadi, and Gary H. Perdew. Mechanistic Insights into the Events That Lead to Synergistic Induction of Interleukin 6 Transcription upon Activation of the Aryl Hydrocarbon Receptor and Inflammatory Signaling.
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Colin P. Sharp, Matthew LeBreton, Kalle Kantola, Ahmadou Nana, Joseph Le Doux Diffo, Cyrille F. Djoko, Ubald Tamoufe, John A. Kiyang, Tafon G. Babila, Eitel Mpoudi Ngole, Oliver G. Pybus, Eric Delwart, Eric Delaporte, Martine Peeters, Maria Soderlund-Venermo, Klaus Hedman, Nathan D. Wolfe, and Peter Simmonds. Widespread Infection with Homologues of Human Parvoviruses B19, PARV4, and Human Bocavirus of Chimpanzees and Gorillas in the Wild.
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Clementina Dellomonaco, Carlos Rivera, Paul Campbell, and Ramon Gonzalez. Engineered Respiro-Fermentative Metabolism for the Production of Biofuels and Biochemicals from Fatty Acid-Rich Feedstocks.
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Gwendal Dujardin, Emanuele Buratti, Nicolas Charlet-Berguerand, Mafalda Martins de Araujo, Annick Mbopda, Catherine Le Jossic-Corcos, Franco Pagani, Claude Ferec, and Laurent Corcos. CELF proteins regulate CFTR pre-mRNA splicing: essential role of the divergent domain of ETR-3.
Nucleic Acids Res.
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Elizabeth Stansell and Ronald C. Desrosiers. Fundamental Difference in the Content of High-Mannose Carbohydrate in the HIV-1 and HIV-2 Lineages.
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Antonis Voutetakis, Ana P. Cotrim, Anne Rowzee, Changyu Zheng, Trushar Rathod, Tulin Yanik, Y. Peng Loh, Bruce J. Baum, and Niamh X. Cawley. Systemic Delivery of Bioactive Glucagon-Like Peptide 1 after Adenoviral-Mediated Gene Transfer in the Murine Salivary Gland.
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Cam T. Ha, Julie A. Wu, Ster Irmak, Felipe A. Lisboa, Anne M. Dizon, James W. Warren, Suleyman Ergun, and Gabriela S. Dveksler. Human Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Has a Potential Role in Placental Vascular Morphogenesis.
Biol Reprod.
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Melissa A. Stern, Chunling Hu, Dyana T. Saenz, Hind J. Fadel, Olivia Sims, Mary Peretz, and Eric M. Poeschla. Productive Replication of
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Ashwini Mishra, Sudharshan Eathiraj, Silvia Corvera, and David G. Lambright. Structural basis for Rab GTPase recognition and endosome tethering by the C
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Shengchun Wang, Xiaoching Zhao, Robert Suran, Volker M. Vogt, John T. Lis, and Hua Shi. Knocking down gene function with an RNA aptamer expressed as part of an intron.
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Oh HL, Akerström S, Shen S, Bereczky S, Karlberg H, Klingström J, Lal SK, Mirazimi A, Tan YJ. An Antibody against a Novel and Conserved Epitope in the Hemagglutinin 1 Subunit Neutralizes Numerous H5N1 Influenza Viruses.
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Larue RS, Lengyel J, Jónsson SR, Andrésdóttir V, Harris RS. Lentiviral Vif Degrades the APOBEC3Z3/APOBEC3H Protein of Its Mammalian Host and Is Capable of Cross-Species Activity.
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Christopher T. Pappas, Paul A. Krieg, and Carol C. Gregorio. Nebulin regulates actin filament lengths by a stabilization mechanism.
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Kwang Soon Kim, Dong Bin Jin, So Shin Ahn, Ki Seok Park, Sang Hwan Seo, You Suk Suh, and Young Chul Sung. HIV-1 Protease Has a Genetic T-Cell Adjuvant Effect Which Is Negatively Regulated by Proteolytic Activity.
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B. Renee Bozard, Preethi S. Ganapathy, Jennifer Duplantier, Barbara Mysona, Yonju Ha, Penny Roon, Robert Smith, I. David Goldman, Puttur Prasad, Pamela M. Martin, Vadivel Ganapathy, and Sylvia B. Smith. Molecular and Biochemical Characterization of Folate Transport Proteins in Retinal Müller Cells.
Invest. Ophthalmol. Vis. Sci.
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Eti Meiri, Asaf Levy, Hila Benjamin, Miriam Ben-David, Lahav Cohen, Avital Dov, Nir Dromi, Eran Elyakim, Noga Yerushalmi, Orit Zion, Gila Lithwick-Yanai, and Einat Sitbon. Discovery of microRNAs and other small RNAs in solid tumors.
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Hyka P, Züllig T, Ruth C, Looser V, Meier C, Klein J, Melzoch K, Meyer HP, Glieder A, Kovar K. Combined Use of Fluorescent Dyes and Flow Cytometry To Quantify the Physiological State of Pichia pastoris during the Production of Heterologous Proteins in High-Cell-Density Fed-Batch Cultures.
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Chao-Yin Cheng, Alexander Vogt, Kazufumi Mochizuki, and Meng-Chao Yao. A Domesticated piggyBac Transposase Plays Key Roles in Heterochromatin Dynamics and DNA Cleavage during Programmed DNA Deletion in
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V. Chico, A. Martinez-Lopez, M. Ortega-Villaizan, A. Falco, L. Perez, J. M. Coll, and A. Estepa. Pepscan Mapping of Viral Hemorrhagic Septicemia Virus Glycoprotein G Major Lineal Determinants Implicated in Triggering Host Cell Antiviral Responses Mediated by Type I Interferon.
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Amy Marie Yu and Mitch McVey. Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions.
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Efrem S. Lim, Harmit S. Malik, and Michael Emerman. Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses.
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Frances L. Shaw, Katherine A. Elliott, Lisa N. Kinch, Christine Fuell, Margaret A. Phillips, and Anthony J. Michael. Evolution and Multifarious Horizontal Transfer of an Alternative Biosynthetic Pathway for the Alternative Polyamine sym-Homospermidine.
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Gregory B. Gloor, Gaurav Tyagi, Dana M. Abrassart, Andrew J. Kingston, Andrew D. Fernandes, Stanley D. Dunn, and Christopher J. Brandl. Functionally Compensating Coevolving Positions Are Neither Homoplasic Nor Conserved in Clades.
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Marcus E. Shin, Aikaterini Skokotas, and Edward Winter. The Cdk1 and Ime2 Protein Kinases Trigger Exit from Meiotic Prophase in
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Mol. Cell Biol.
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Ahmed Gaballa, Gerald L. Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C. Fahey, and John D. Helmann. Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
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N.G. Brown and T. Palzkill. Identification and characterization of β-lactamase inhibitor protein-II (BLIP-II) interactions with β-lactamases using phage display.
Protein Eng. Des. Sel.
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Maurits N.C. de Koning, Jan ter Schegget, Just A.H. Eekhof, Marga Kamp, Bernhard Kleter, Jacobijn Gussekloo, Mariet C.W. Feltkamp, Jan Nico Bouwes Bavinck, Karin J. Purdie, Christopher B. Bunker, Charlotte M. Proby, Rhonda Meys, Catherine A. Harwood, and Wim G.V. Quint. Evaluation of a novel broad-spectrum PCR-multiplex genotyping assay for identification of cutaneous wart-associated human papillomavirus types.
J. Clin. Microbiol.
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Maria A. Schumacher, Kevin M. Piro, and Weijun Xu. Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes.
Nucleic Acids Res.
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Eva Lee, Sook Kwan Leang, Andrew Davidson, and Mario Lobigs. Both E protein glycans adversely affect dengue virus infectivity but are beneficial for virion release.
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Judith M. Gottwein, Troels K.H. Scheel, Benoit Callendret, Yi-Ping Li, Heather B. Eccleston, Ronald E. Engle, Sugantha Govindarajan, William Satterfield, Robert H. Purcell, Christopher M. Walker, and Jens Bukh. Novel Infectious cDNA Clones of Hepatitis C Virus Genotype 3a (Strain S52) and 4a (Strain ED43): Genetic Analyses and In Vivo Pathogenesis Studies.
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Marion Avril, Megan M. Cartwright, Marianne J. Hathaway, Mirja Hommel, Salenna R. Elliott, Kathryn Williamson, David L. Narum, Patrick E. Duffy, Michal Fried, James G. Beeson, and Joseph D. Smith. Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental-type
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Infect Immun.
2010-5; NULL(NULL): NULL
Toni Hoffmann, Lukas Kurt Josef Stadler, Michael Busby, Qifeng Song, Anthony T. Buxton, Simon D. Wagner, Jason J. Davis, and Paul Ko Ferrigno. Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant.
Protein Eng. Des. Sel.
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Laura Owens, Scott Simanski, Christopher Squire, Anthony Smith, Jeff Cartzendafner, Valerie Cavett, Jennifer Caldwell Busby, Trey Sato, and Nagi G. Ayad. Activation Domain-dependent Degradation of Somatic Wee1 Kinase.
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Nobuo Maita, James Nyirenda, Mayumi Igura, Jun Kamishikiryo, and Daisuke Kohda. Comparative Structural Biology of Eubacterial and Archaeal Oligosaccharyltransferases.
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Andrew J. Holland, Weijie Lan, Sherry Niessen, Heather Hoover, and Don W. Cleveland. Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability.
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Mera PE, Escalante-Semerena JC. Dihydroflavin-driven adenosylation of 4-coordinate Co(II) corrinoids: are cobalamin reductases enzymes or electron transfer proteins?
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Amarjit S. Chaudhry, Thomas J. Urban, Jatinder K. Lamba, Angela K. Birnbaum, Rory P. Remmel, Murali Subramanian, Stephen Strom, Joyce H. You, Dalia Kasperaviciute, Claudia B. Catarino, Rodney A. Radtke, Sanjay M. Sisodiya, David B. Goldstein, and Erin G. Schuetz.
CYP2C9*1B
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Aruna Natarajan, Guichun Han, Shi-you Chen, Peiying Yu, Richard White, and Pedro Jose. The D
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Anissa M. Jabbour, Carmel P. Daunt, Benjamin D. Green, Sandra Vogel, Lavinia Gordon, Rachel S. Lee, Natasha Silke, Richard B. Pearson, Cassandra J. Vandenberg, Priscilla N. Kelly, Stephen L. Nutt, Andreas Strasser, Christoph Borner, and Paul G. Ekert. Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.
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Mookkan Prabakaran, Selvaraj Madhan, Nayana Prabhu, Jia Qiang, and Jimmy Kwang. Gastrointestinal delivery of baculovirus displaying influenza hemagglutinin protects mice against heterologous H5N1 infection.
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Chantal Fernandes, Vitor Mendes, Joana Costa, Nuno Empadinhas, Carla Jorge, Pedro Lamosa, Helena Santos, and Milton S. da Costa. Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in
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Jin-Shu He, Dong-Er Gong, and Hanne L. Ostergaard. Stored Fas Ligand, a Mediator of Rapid CTL-Mediated Killing, Has a Lower Threshold for Response Than Degranulation or Newly Synthesized Fas Ligand.
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Ye Dee Tay, Julie M. Sidebotham, and Leonard Wu. Mph1 requires mismatch repair-independent and -dependent functions of MutSα to regulate crossover formation during homologous recombination repair.
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Oppegård C, Emanuelsen L, Thorbek L, Fimland G, Nissen-Meyer J. The Lactococcin G Immunity Protein Recognizes Specific Regions in Both Peptides Constituting the Two-Peptide Bacteriocin Lactococcin G.
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David C. F. Sealey, Le Zheng, Michael A. S. Taboski, Jennifer Cruickshank, Mitsuhiko Ikura, and Lea A. Harrington. The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization.
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Christopher A. Koczor, Inna N. Shokolenko, Amy K. Boyd, Shawn P. Balk, Glenn L. Wilson, and Susan P. LeDoux. Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells.
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Alessio Montresor, Matteo Bolomini-Vittori, Scott I. Simon, Antonella Rigo, Fabrizio Vinante, and Carlo Laudanna. Comparative Analysis of Normal versus CLL B-Lymphocytes Reveals Patient-Specific Variability in Signaling Mechanisms Controlling LFA-1 Activation by Chemokines.
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Dobó J, Varga J, Sajó R, Végh BM, Gál P, Závodszky P, Vonderviszt F. Application of a Short, Disordered N-Terminal Flagellin Segment, a Fully Functional Flagellar Type III Export Signal, to Expression of Secreted Proteins.
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Chen Chen, Jing Jin, D. Andrew James, Melanie A. Adams-Cioaba, Jin Gyoon Park, Yahong Guo, Enrico Tenaglia, Chao Xu, Gerald Gish, Jinrong Min, and Tony Pawson. Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi.
PNAS.
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Robbert M. Spaapen, Ron A.L. de Kort, Kelly van den Oudenalder, Maureen van Elk, Andries C. Bloem, Henk M. Lokhorst, and Tuna Mutis. Rapid Identification of Clinical Relevant Minor Histocompatibility Antigens via Genome-Wide Zygosity-Genotype Correlation Analysis.
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Pey-Shynan JAN, Hsu-Yuang Huang, and Hueih-Min CHEN. Expression of synthesized gene encoding cationic peptide cecropin B in transgenic tomato protects against bacterial diseases.
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Herget M, Kreissig N, Kolbe C, Schölz C, Tampé R, Abele R. Purification and Reconstitution of the Antigen Transport Complex TAP: A PREREQUISITE FOR DETERMINATION OF PEPTIDE STOICHIOMETRY AND ATP HYDROLYSIS.
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Justin Hall, P. Andrew Karplus, and Elisar Barbar. Multivalency in the Assembly of Intrinsically Disordered Dynein Intermediate Chain.
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Ellen J. Collarini, F. Eun-Hyung Lee, Orit Foord, Minha Park, Gizette Sperinde, Hai Wu, William D. Harriman, Stephen F. Carroll, Stote L. Ellsworth, Larry J. Anderson, Ralph A. Tripp, Edward E. Walsh, Bruce A. Keyt, and Lawrence M. Kauvar. Potent High-Affinity Antibodies for Treatment and Prophylaxis of Respiratory Syncytial Virus Derived from B Cells of Infected Patients.
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Hiroaki Ishida, Mario Rainaldi, and Hans J. Vogel. Structural Studies of Soybean Calmodulin Isoform 4 Bound to the Calmodulin-binding Domain of Tobacco Mitogen-activated Protein Kinase Phosphatase-1 Provide Insights into a Sequential Target Binding Mode.
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Senger T, Becker MR, Schädlich L, Waterboer T, Gissmann L. Identification of B-cell epitopes on VLPs of cutaneous alpha HPVs.
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Sang-Keun Oh, Carolyn Young, Minkyoung Lee, Ricardo Oliva, Tolga O. Bozkurt, Liliana M. Cano, Joe Win, Jorunn I.B. Bos, Hsin-Yin Liu, Mireille van Damme, William Morgan, Doil Choi, Edwin A.G. Van der Vossen, Vivianne G.A.A. Vleeshouwers, and Sophien Kamoun. In Planta Expression Screens of
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Alessio Lombardi, Sara Bursomanno, Teresa Lopardo, Roberta Traini, Marco Colombatti, Rodolfo Ippoliti, David J. Flavell, Sopsamorn U. Flavell, Aldo Ceriotti, and Maria Serena Fabbrini.
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Isabel Molina, Yonghua Beisson-Li, Fred Beisson, John B. Ohlrogge, and Mike Pollard. Identification of an Arabidopsis Feruloyl-CoA Transferase Required for Suberin Synthesis.
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Chau H. Nguyen, Hong Ming, Peishen Zhao, Lynne Hugendubler, Robert Gros, Scot R. Kimball, and Peter Chidiac. Translational control by RGS2.
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Xu Q, Traag BA, Willemse J, McMullan D, Miller MD, Elsliger MA, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chruszcz M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J, Grant JC, Grzechnik A, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Krishna SS, Kumar A, Marciano D, Minor W, Mommaas AM, Morse AT, Nigoghossian E, Nopakun A, Okach L, Oommachen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Wang S, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA, van Wezel GP. Structural and Functional Characterizations of SsgB, a Conserved Activator of Developmental Cell Division in Morphologically Complex Actinomycetes.
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Efrem Lim and Michael Emerman. Simian Immunodeficiency Virus SIV
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Sina Mohammadi and Ralph R. Isberg.
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Rahul M. Kohli, Shaun R. Abrams, Kiran S. Gajula, Robert W. Maul, Patricia J. Gearhart, and James T. Stivers. A Portable Hot Spot Recognition Loop Transfers Sequence Preferences from APOBEC Family Members to Activation-induced Cytidine Deaminase.
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Baerends RJ, Qiu JL, Rasmussen S, Nielsen HB, Brandt A. Impaired uptake and/or utilisation of leucine is suppressed by the
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Rui Wang, Kannan Natarajan, and David H. Margulies. Structural Basis of the CD8{alpha}β/MHC Class I Interaction: Focused Recognition Orients CD8β to a T Cell Proximal Position.
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Michael H. Norris, Yun Kang, Diana Lu, Bruce A. Wilcox, and Tung T. Hoang. Glyphosate Resistance as a Novel Select-Agent-Compliant Non-antibiotic Selectable-Marker: Chromosomal Mutagenesis of the Essential
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Adam C. Martiny, Satish Kathuria, and Paul M. Berube. From the Cover: Widespread metabolic potential for nitrite and nitrate assimilation among
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Milosz Faber, Jianwei Li, Rhonda B. Kean, D. Craig Hooper, Kishore R. Alugupalli, and Bernhard Dietzschold. Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus.
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Robin M. Vos, Jennifer Altreuter, Elizabeth A. White, and Peter M. Howley. The Ubiquitin Specific Peptidase USP15 Regulates Human Papilloma Virus 16 E6 Protein Stability.
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Ryo Ueda, Gary Kohanbash, Kotaro Sasaki, Mitsugu Fujita, Xinmei Zhu, Edward R. Kastenhuber, Heather A. McDonald, Douglas M. Potter, Ronald L. Hamilton, Michael T. Lotze, Saleem A. Khan, Robert W. Sobol, and Hideho Okada. Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.
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Nobutaka Nakashima and Tomohiro Tamura. Conditional gene silencing of multiple genes with antisense RNAs and generation of a mutator strain of
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Takayuki Sohka, Richard A. Heins, Ryan M. Phelan, Jennifer M. Greisler, Craig A. Townsend, and Marc Ostermeier. An externally tunable bacterial band-pass filter.
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Kassa A, Madani N, Schön A, Haim H, Finzi A, Xiang SH, Wang L, Princiotto A, Pancera M, Courter J, Smith AB 3rd, Freire E, Kwong PD, Sodroski J. Transitions to and from the CD4-bound Conformation are Modulated by a Single-Residue Change in the HIV-1 gp120 Inner Domain.
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Shane B. Claggett, Mac O'Neil Plancher, Stanley D. Dunn, and Brian D. Cain. The b Subunits in the Peripheral Stalk of F
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Farid A. Kadyrov, Jochen Genschel, Yanan Fang, Elisabeth Penland, Winfried Edelmann, and Paul Modrich. A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.
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Ellen Z. Baum, Steven M. Crespo-Carbone, Brian J. Morrow, Todd A. Davies, Barbara D. Foleno, Wenping He, Anne Marie Queenan, and Karen Bush. Effect of MexXY Overexpression on Ceftobiprole Susceptibility in
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Alan S. Lewis, Emily Schwartz, C. Savio Chan, Yoav Noam, Minyoung Shin, Wytse J. Wadman, D. James Surmeier, Tallie Z. Baram, Robert L. Macdonald, and Dane M. Chetkovich. Alternatively Spliced Isoforms of TRIP8b Differentially Control h Channel Trafficking and Function.
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Pribat A, Jeanguenin L, Lara-Núñez A, Ziemak MJ, Hyde JE, de Crécy-Lagard V, Hanson AD. 6-Pyruvoyltetrahydropterin Synthase Paralogs Replace the Folate Synthesis Enzyme Dihydroneopterin Aldolase in Diverse Bacteria.
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Feng Rao, Yaning Qi, Hui Shan Chong, Masayo Kotaka, Bin Li, Jinming Li, Julien Lescar, Kai Tang, and Zhao-Xun Liang. The Functional Role of a Conserved Loop in EAL Domain-Based C-di-GMP Specific Phosphodiesterase.
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Shang L. Lian, Songqing Li, Grant X. Abadal, Brad A. Pauley, Marvin J. Fritzler, and Edward K.L. Chan. The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing.
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Yao-Cheng Ching, Chen-Sheng Chung, Cheng-Yen Huang, Yu Hsia, Yin-Liang Tang, and Wen Chang. Disulfide bond formation at the C-termini of vaccinia A26 and A27 proteins does not require viral redox enzymes and suppresses glycosaminoglycan-mediated cell fusion.
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Jakob Loschko, Andreas Schlitzer, Diana Dudziak, Ingo Drexler, Nadja Sandholzer, Carole Bourquin, Wolfgang Reindl, and Anne B. Krug. Antigen Delivery to Plasmacytoid Dendritic Cells via BST2 Induces Protective T Cell-Mediated Immunity.
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Hao Zhang, Wei Shen, Don Rempel, John Monsey, Ilan Vidavsky, Michael L. Gross, and Ron Bose. Carboxyl-Group Footprinting Maps the Dimerization Interface and Phosphorylation-induced Conformational Changes of a Membrane-associated Tyrosine Kinase.
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David S, Ghosh CC, Kümpers P, Shushakova N, Van Slyke P, Khankin EV, Karumanchi SA, Dumont D, Parikh SM. Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality.
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Ayumi Yoshizumi, Jordan M. Fletcher, Zhuoxin Yu, Anton V. Persikov, Gail J. Bartlett, Aimee L. Boyle, Thomas L. Vincent, Derek N. Woolfson, and Barbara Brodsky. Designed Coiled Coils Promote Folding of a Recombinant Bacterial Collagen.
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Rebecca L. Heise, Vandy Stober, Chaitra Cheluvaraju, John W. Hollingsworth, and Stavros Garantziotis. Mechanical Stretch Induces Epithelial-Mesenchymal Transition in Alveolar Epithelia via Hyaluronan Activation of Innate Immunity.
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Corey Smith, Michelle Martinez, Jesse Peet, and Rajiv Khanna. Differential Outcome of IL-2/Anti-IL-2 Complex Therapy on Effector and Memory CD8
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Vanessa K. Morris, Qin Ren, Ingrid Macindoe, Ann H. Kwan, Nolene Byrne, and Margaret Sunde. Recruitment of Class I Hydrophobins to the Air:Water Interface Initiates a Multi-step Process of Functional Amyloid Formation.
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Narayan V, Halada P, Hernychová L, Chong YP, Žáková J, Hupp TR, Vojtesek B, Ball KL. A Multiprotein Binding Interface in an Intrinsically Disordered Region of the Tumor Suppressor Protein Interferon Regulatory Factor-1.
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Pawel Stocki, Xiao N. Wang, Nicholas J. Morris, and Anne M. Dickinson. HSP70 Natively and Specifically Associates with an N-terminal Dermcidin-derived Peptide That Contains an HLA-A*03 Antigenic Epitope.
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Christopher C. DeNucci and Yoji Shimizu. β1 Integrin Is Critical for the Maintenance of Antigen-Specific CD4 T Cells in the Bone Marrow but Not Long-Term Immunological Memory.
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Avanish K. Varshney, Xiaobo Wang, Emily Cook, Kaushik Dutta, Matthew D. Scharff, Michael J. Goger, and Bettina C. Fries. Generation, Characterization, and Epitope Mapping of Neutralizing and Protective Monoclonal Antibodies against Staphylococcal Enterotoxin B-induced Lethal Shock.
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Mol. Cell. Proteomics.
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Rigato PO, de Alencar BC, de Vasconcelos JR, Dominguez MR, Araújo AF, Machado AV, Gazzinelli RT, Bruna-Romero O, Rodrigues MM. Heterologous Plasmid DNA Prime-Recombinant Human Adenovirus 5 Boost Vaccination Generates a Stable Pool of Protective Long-Lived CD8
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Cong Peng, Yong-Yeon Cho, Feng Zhu, Jishuai Zhang, Weihong Wen, Yanming Xu, Ke Yao, Wei-Ya Ma, Ann M. Bode, and Zigang Dong. Phosphorylation of Caspase-8 (Thr-263) by Ribosomal S6 Kinase 2 (RSK2) Mediates Caspase-8 Ubiquitination and Stability.
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Cuesto G, Enriquez-Barreto L, Caramés C, Cantarero M, Gasull X, Sandi C, Ferrús A, Acebes á, Morales M. Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons.
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Kimiko M. Tsutsui, Kuniaki Sano, Osamu Hosoya, Tadashi Miyamoto, and Ken Tsutsui. Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain.
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Andrew Morin, Kristian W. Kaufmann, Carie Fortenberry, Joel M. Harp, Laura S. Mizoue, and Jens Meiler. Computational design of an endo-1,4-β-xylanase ligand binding site.
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Shanjana Awasthi, Kevin Brown, Catherine King, Vibhudutta Awasthi, and Rajkumar Bondugula. A Toll-Like Receptor-4-Interacting Surfactant Protein-A-Derived Peptide Suppresses Tumor Necrosis Factor-α Release from Mouse JAWS II Dendritic Cells.
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Oleg Y. Borbulevych, Kurt H. Piepenbrink, and Brian M. Baker. Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
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Naoki Tanaka, Yumi Morimoto, Yurika Noguchi, Tomoko Tada, Tomonori Waku, Shigeru Kunugi, Takashi Morii, Yin-Fai Lee, Takashi Konno, and Nobuyuki Takahashi. The Mechanism of Fibril Formation of a Non-inhibitory Serpin Ovalbumin Revealed by the Identification of Amyloidogenic Core Regions.
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Feiran Gong, Luan Sun, Zongdan Wang, Junfeng Shi, Wei Li, Sumeng Wang, Xiao Han, and Yujie Sun. The BCL2 gene is regulated by a special AT-rich sequence binding protein 1-mediated long range chromosomal interaction between the promoter and the distal element located within the 3'-UTR.
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Ken Nishimura, Masayuki Sano, Manami Ohtaka, Birei Furuta, Yoko Umemura, Yoshiro Nakajima, Yuzuru Ikehara, Toshihiro Kobayashi, Hiroaki Segawa, Satoko Takayasu, Hideyuki Sato, Kaori Motomura, Eriko Uchida, Toshie Kanayasu-Toyoda, Makoto Asashima, Hiromitsu Nakauchi, Teruhide Yamaguchi, and Mahito Nakanishi. Development of Defective and Persistent Sendai Virus Vector: A UNIQUE GENE DELIVERY/EXPRESSION SYSTEM IDEAL FOR CELL REPROGRAMMING.
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Busam RD, Thorsell AG, Flores A, Hammarström M, Persson C, öbrink B, Hallberg BM. Structural Basis of Tumor Suppressor in Lung Cancer 1 (TSLC1) Binding to Differentially Expressed in Adenocarcinoma of the Lung (DAL-1/4.1B).
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Lisa L. Maduzia, Evan Yu, and Yinhua Zhang.
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Elena R. Virtue, Glenn A. Marsh, and Lin-Fa Wang. Interferon Signaling Remains Functional during Henipavirus Infection of Human Cell Lines.
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Juan Wang, Yu Ding, Junqi Wang, Stefan Hillmer, Yansong Miao, Sze Wan Lo, Xiangfeng Wang, David G. Robinson, and Liwen Jiang. EXPO, an Exocyst-Positive Organelle Distinct from Multivesicular Endosomes and Autophagosomes, Mediates Cytosol to Cell Wall Exocytosis in
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Haugen HS, Fimland G, Nissen-Meyer J. Mutational Analysis of Residues in the Helical Region of the Class IIa Bacteriocin Pediocin PA-1.
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Saji Oommen, Shiv K. Gupta, and Nicholas E. Vlahakis. Vascular Endothelial Growth Factor A (VEGF-A) Induces Endothelial and Cancer Cell Migration through Direct Binding to Integrin α9β1: IDENTIFICATION OF A SPECIFIC α9β1 BINDING SITE.
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Yasser A. Aldhamen, Daniel M. Appledorn, Sergey S. Seregin, Chyong-jy J. Liu, Nathaniel J. Schuldt, Sarah Godbehere, and Andrea Amalfitano. Expression of the SLAM Family of Receptors Adapter EAT-2 as a Novel Strategy for Enhancing Beneficial Immune Responses to Vaccine Antigens.
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Suranga P. Kodithuwakku, Pak-Yiu Ng, Yunao Liu, Ernest H.Y. Ng, William S.B. Yeung, Pak-Chung Ho, and Kai-Fai Lee. Hormonal regulation of endometrial olfactomedin expression and its suppressive effect on spheroid attachment onto endometrial epithelial cells.
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Rahmawati Ridwan, Paul Kiptoo, Naoki Kobayashi, Scott Weir, Michael Hughes, Todd Williams, Rondang Soegianto, and Teruna J. Siahaan. Antigen-Specific Suppression of Experimental Autoimmune Encephalomyelitis by a Novel Bifunctional Peptide Inhibitor: Structure Optimization and Pharmacokinetics.
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2009-5; 83(9): 4127 - 4139
Immunochemistry Services
Degn SE, Hansen AG, Steffensen R, Jacobsen C, Jensenius JC, Thiel S. MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation.
J. Immunol.
2009-12; 183(11): 7371 - 7378
Cellular Analysis
JN Ho, HG Yoon, CS Park, S Kim, W Jun, R Choue Isothiocyanates Ameliorate The Symptom Of Heart Dysfunction And Mortality In A Murine Aids Model By Inhibiting Apoptosis In The Left Ventricle.
Journal of Medicinal Food.
2012-8; 15(9): 781 - 7
PK Manchanda, GN Jones, AA Lee, DR Pringle Rac1 Is Required For Prkar1A-Mediated Nf2 Suppression In Schwann Cell Tumors.
Oncogene.
2012-10; NULL(NULL): NULL
Gabay O, Sanchez C, Dvir-Ginzberg M, Gagarina V, Zaal KJ, Song Y, He XH, McBurney MW. Sirt1 enzymatic activity is required for cartilage homeostasis in vivo.
Arthritis & Rheumatism.
2013-1; NULL(NULL): NULL
Sanchita P. Ghosh, Shilpa Kulkarni, Michael W. Perkins, Kevin Hieber, Roli L. Pessu, Kristen Gambles, Manoj Maniar, Tzu-Cheg Kao, Thomas M. Seed, and K. Sree Kumar Amelioration Of Radiation-Induced Hematopoietic And Gastrointestinal Damage By Ex-Rad(R) In Mice.
J Radiat Res.
2012-7; 53(4): 526 - 536
P. Lirk, R. Berger, M.W. Hollmann, and H. Fiegl Lidocaine Time- And Dose-Dependently Demethylates Deoxyribonucleic Acid In Breast Cancer Cell Lines In Vitro.
Br. J. Anaesth.
2012-8; 109(2): 200 - 207
Vasudevan A, Won C, Li S, Erdélyi F, Szabó G, Kim KS. Dopaminergic Neurons Modulate Gaba Neuron Migration In The Embryonic Midbrain.
Development.
2012-9; 139(17): 3136 - 3141
He L, Kim T, Long Q, Liu J, Wang P, Zhou Y, Ding Y, Prasain J, Wood PA, Yang Q. Carnitine palmitoyltransferase-1b deficiency aggravates pressure overload¯induced cardiac hypertrophy caused by lipotoxicity.
Circulation.
2012-10; 126(14): 1705 - 1716
Trokovic N, Pöllänen R, Porola P, Stegaev V, Hetzel U, Tivesten å, Engdahl C, Carlsten H, Forsblad-d′Elia H, Fagman JB, Lagerquist M, Konttinen YT. Exosomal secretion of death bullets: a new way of apoptotic escape?
Am J Physiol Endocrinol Metab.
2012-10; 303(8): E1015 - E1024
Du H, Hamilton P, Reilly M, Ravi N. Injectable in situ Physically and Chemically Crosslinkable Gellan Hydrogel.
Macromol Biosci.
2012-7; NULL(NULL): NULL
Vojtech LN, Scharping N, Hansen JD. Processing of zebrafish interleukin-1 beta during Francisella noatunensis infection: roles of inflammatory caspases.
Infect Immun.
2012-8; NULL(NULL): NULL
Tenbaum SP, Ordóñez-Morán P, Puig I, Chicote I, Arqués O, Landolfi S, Fernández Y, Herance JR, Gispert JD, Mendizabal L, Aguilar S, Ramón y Cajal S, Schwartz S Jr, Vivancos A, Espín E, Rojas S, Baselga J, Tabernero J, Muñoz A, Palmer HG. Β-Catenin Confers Resistance To Pi3K And Akt Inhibitors And Subverts Foxo3A To Promote Metastasis In Colon Cancer.
Nat Med.
2012-5; NULL(NULL): NULL
Singh VK, Fatanmi OO, Singh PK, Whitnall MH. Role of radiation-induced granulocyte colony-stimulating factor in recovery from whole body gamma-irradiation.
Cytokine.
2012-6; NULL(NULL): NULL
Mulligan CM, Sparagna GC, Le CH, De Mooy AB, Routh MA, Holmes MG, Hickson-Bick DL, Zarini S, Murphy RC, Xu FY, Hatch GM, McCune SA, Moore RL, Chicco AJ. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart.
Cardiovasc Res.
2012-6; NULL(NULL): NULL
Samarakoon SR, Thabrew I, Galhena PB, Tennekoon KH. Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of nigella sativa seeds, hemidesmus indicus roots and smilax glabra rhizomes with anti- hepatocarcinogenic effects.
BMC Complement Altern Med.
2012-3; NULL(NULL): NULL
Ullah I, Ullah N, Imran Naseer M, Lee HY, Kim MO. Neuroprotection With Metformin And Thymoquinone Against Ethanol-Induced Apoptotic Neurodegeneration In Prenatal Rat Cortical Neurons.
BMC Neurosci.
2012; 13(1): 11
Shah M, Ullah N, Choi MH, Kim MO, Yoon SC. Amorphous amphiphilic P(3HV-co-4HB)-b-mPEG block copolymer synthesized from bacterial copolyester via melt transesterification: Nanoparticle preparation, cisplatin-loading for cancer therapy and in vitro evaluation.
Eur J Pharm Biopharm.
2012-4; NULL(NULL): NULL
Li R, Mittelstein D, Fang K, Beebe T, Quigley K, Berliner J, Hsiai TK. Angiopoeitin-2 modulates Survivin expression in OxLDL-induced endothelial cell apoptosis.
Biochem Biophys Res Commun.
2012-1; 417(1): 619-22
Jumana M. Yousef, Gong Chen, Prue A. Hill, Roger L. Nation, and Jian Li Ascorbic Acid Protects Against The Nephrotoxicity And Apoptosis Caused By Colistin And Affects Its Pharmacokinetics.
J. Antimicrob. Chemother
2012-2; NULL(NULL): NULL
Caroline B. Appleyard, Myrella L. Cruz, Angel A. Isidro, Janelle C. Arthur, Christian Jobin, and Claudio De Simone Pretreatment With The Probiotic Vsl#3 Delays Transition From Inflammation To Dysplasia In A Rat Model Of Colitis-Associated Cancer.
Am J Physiol Gastrointest Liver Physiol.
2011-12; 301(6): G1004 - G1013
Goebel G, Berger R, Strasak AM, Egle D, Müller-Holzner E, Schmidt S, Rainer J, Presul E, Parson W, Lang S, Jones A, Widschwendter M, Fiegl H. Elevated Mrna Expression Of Chac1 Splicing Variants Is Associated With Poor Outcome For Breast And Ovarian Cancer Patients.
British Journal of Cancer
2012-1; NULL(NULL): NULL
özata DM, Caramuta S, Velázquez-Fernández D, Ak?kaya P, Xie H, Höög A, Zedenius J, Bäckdahl M, Larsson C, Lui WO. The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma.
Endocr. Relat. Cancer.
2011-10; 18(6): 643 - 655
Sörensen I, Rong S, Susnik N, Gueler F, Shushakova N, Albrecht M, Dittrich AM, von Vietinghoff S, Becker JU, Melk A, Bohlmann A, Reingruber S, Petzelbauer P, Haller H, Schmitt R. Bβ
15-42
Attenuates the Effect of Ischemia-Reperfusion Injury in Renal Transplantation.
J. Am. Soc. Nephrol.
2011-10; 22(10): 1887 - 1896
Carmignac V, Svensson M, Körner Z, Elowsson L, Matsumura C, Gawlik KI, Allamand V, Durbeej M. Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A.
Hum Mol Genet.
2011-12; NULL(NULL): NULL
Giovanni Luca Gravina, Francesco Marampon, Foteini Petini, Leda Biordi, David Sherris, Emmanuele A Jannini, Vincenzo Tombolini, and Claudio Festuccia. The TORC1/TORC2 inhibitor, Palomid 529, reduces tumor growth and sensitizes to docetaxel and cisplatin in aggressive and hormone-refractory prostate cancer cells.
Endocr. Relat. Cancer.
2011-7; 18(4): 385 - 400
Forman K, Vara E, García C, Kireev R, Cuesta S, Escames G, Tresguerres JA. Effect of a Combined Treatment With Growth Hormone and Melatonin in the Cardiological Aging on Male SAMP8 Mice.
J Gerontol A Biol Sci Med Sci.
2011-8; NULL(NULL): NULL
Quéré R, Karlsson G, Hertwig F, Rissler M, Lindqvist B, Fioretos T, Vandenberghe P, Slovak ML, Cammenga J, Karlsson S. Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation.
Blood.
2011-6; 117(22): 5918 - 5930
Benjamin Drew Rockett, Andrew Franklin, Mitchel Harris, Heather Teague, Alexis Rockett, and Saame Raza Shaikh. Membrane Raft Organization Is More Sensitive to Disruption by (n-3) PUFA Than Nonraft Organization in EL4 and B Cells.
J. Nutr.
2011-6; 141(6): 1041 - 1048
Radin JN, González-Rivera C, Ivie SE, McClain MS, Cover TL.
Helicobacter pylori
VacA induces programmed necrosis in gastric epithelial cells.
Infect Immun.
2011-7; NULL(NULL): NULL
Laurent Sansregret, Charles Vadnais, Julie Livingstone, Nicholas Kwiatkowski, Arif Awan, Chantal Cadieux, Lam Leduy, Michael T. Hallett, and Alain Nepveu. Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.
PNAS.
2011-2; 108(5): 1949 - 1954
Bai-Cheng He, Jian-Li Gao, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Ke Yang, Eric R. Wagner, Linyuan Wang, Ni Tang, Jinyong Luo, Xing Liu, Mi Li, Yang Bi, Jikun Shen, Gaurav Luther, Ning Hu, Qixin Zhou, Hue H. Luu, Rex C. Haydon, Yingming Zhao, and Tong-Chuan He. Tetrandrine Inhibits Wnt/β-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer.
Mol. Pharmacol.
2011-2; 79(2): 211 - 219
Carmignac V, Quéré R, Durbeej M. Proteasome inhibition improves the muscle of laminin α2 chain-deficient mice.
Hum Mol Genet.
2011-2; 20(3): 541 - 552
Pieter Hindryckx, Martine De Vos, Peggy Jacques, Liesbeth Ferdinande, Harald Peeters, Kim Olievier, Sara Bogaert, Brigitta Brinkman, Peter Vandenabeele, Dirk Elewaut, and Debby Laukens. Hydroxylase Inhibition Abrogates TNF-αinduced Intestinal Epithelial Damage by Hypoxia-Inducible Factor-1-dependent Repression of FADD.
J. Immunol.
2010-11; 185(10): 6306 - 6316
Linda Lin-Yan Wu, Kylie R. Dunning, Xing Yang, Darryl L. Russell, Michelle Lane, Robert J. Norman, and Rebecca L. Robker. High-Fat Diet Causes Lipotoxicity Responses in Cumulus-oocyte Complexes and Decreased Fertilization Rates.
Endocrinology.
2011-11; 151(11): 5438 - 5445
Zhongfang Wang, Nicole C. Robb, Eva Lenz, Thorsten Wolff, Ervin Fodor, and Stephan Pleschka. NS Reassortment of an H7-Type Highly Pathogenic Avian Influenza Virus Affects Its Propagation by Altering the Regulation of Viral RNA Production and Antiviral Host Response.
J. Virol.
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Daniela Battista and Urs Rutishauser. Removal of Polysialic Acid Triggers Dispersion of Subventricularly Derived Neuroblasts into SurroundingCNS Tissues.
J. Neurosci.
2011-3; 30(11): 3995 - 4003
Click Peptide Service
Linda C. Mota, Juan P. Hernandez, and William S. Baldwin. Constitutive Androgen Receptor-Null Mice Are Sensitive to the Toxic Effects of Parathion: Association with Reduced Cytochrome P450-Mediated Parathion Metabolism.
Drug Metab Dispos.
2012-9; 38(9): 1582 - 1588
Yeast Expression System
Mark Katakowski, Benjamin Buller, Xinli Wang, Thomas Rogers, and Michael Chopp. Functional MicroRNA Is Transferred between Glioma Cells.
Cancer Research.
2010-11; 70(21): 8259 - 8263
Stable Cell Line Services for Protein &
Tomokazu Kurita, Yoichi Noda, Tomoko Takagi, Masako Osumi, and Koji Yoda. Kre6 Protein Essential for Yeast Cell Wall β-1,6-Glucan Synthesis Accumulates at Sites of Polarized Growth.
J. Biol. Chem.
2011-3; 286(9): 7429 - 7438
Cell Lines and Membranes
Tasuku Akiyama, Mirela Iodi Carstens, and E. Carstens. Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model.
J Neurophysiol.
2011-6; 105(6): 2811 - 2817
Preclinical Oncology Services
Giovanni Luca Gravina, Francesco Marampon, Margherita Piccolella, Marcella Motta, Luca Ventura, Roberto Pomante, Vladimir M. Popov, Bianca M. Zani, Richard G. Pestell, Vincenzo Tombolini, Emmanuele A. Jannini, and Claudio Festuccia Hormonal Therapy Promotes Hormone-Resistant Phenotype By Increasing Dnmt Activity And Expression In Prostate Cancer Models.
Endocrinology.
2011-12; 152(12): 4550 - 4561
GPCR Target Solutions
Thiele S, Steen A, Jensen PC, Mokrosinski J, Frimurer TM, Rosenkilde MM. Allosteric And Orthosteric Sites In Cc Chemokine Receptor (Ccr5), A Chimeric Receptor Approach.
J Biol Chem.
2011-10; 286(43): 37543-54
Peptide
Li S, Clémen?n B, Catty P, Brandolin G, Schlattner U, Rousseau D. Yeast-Based Production And Purification Of His-Tagged Human Atad3A, A Specific Target Of S100B.
Protein Expr Purif.
2012-6; 83(2): 211 - 6
Schlenzig D, Rönicke R, Cynis H, Ludwig HH, Scheel E, Reymann K, Saido T, Hause G, Schilling S, Demuth HU. N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation.
J Neurochem.
2012-6; NULL(NULL): NULL
Common Tools
Chacón MR, Navarro AI, Cuesto G, del Pino I, Scott R, Morales M, Rico B. Focal Adhesion Kinase Regulates Actin Nucleation And Neuronal Filopodia Formation During Axonal Growth.
Development.
2012-9; 139(17): 3200 - 3210
Bioinformatics Tools
Casey OM, Fang L, Hynes PG, Abou-Kheir WG, Martin PL, Tillman HS, Petrovics G, Awwad HO, Ward Y, Lake R, Zhang L, Kelly K. Tmprss2-Driven Erg Expression In Vivo Increases Self-Renewal And Maintains Expression In A Castration Resistant Subpopulation.
PLoS ONE.
2012; 7(7): e41668
PolyClonal Antibody Services
Del Re DP, Yang Y, Nakano N, Cho J, Zhai P, Yamamoto T, Zhang N, Yabuta N, Nojima H, Pan D, Sadoshima J. Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury.
J Biol Chem.
2013-02; 288(6): 3977-88
Yabuta N, Mukai S, Okamoto A, Okuzaki D, Suzuki H, Torigata K, Yoshida K, Okada N, Miura D, Ito A, Ikawa M, Okabe M, Nojima H. N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability.
J Cell Sci.
2013-01; 126(Pt 2): 508-20
Nishio M, Hamada K, Kawahara K, Sasaki M, Noguchi F, Chiba S, Mizuno K, Suzuki SO, Dong Y, Tokuda M, Morikawa T, Hikasa H, Eggenschwiler J, Yabuta N, Nojima H, Nakagawa K, Hata Y, Nishina H, Mimori K, Mori M, Sasaki T, Mak TW, Nakano T, Itami S, Suzuki A. Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.
J Clin Invest.
2012-12; 122(12): 4505-18
Naito Y, Shimizu H, Kasama T, Sato J, Tabara H, Okamoto A, Yabuta N, Nojima H. Cyclin G-associated kinase regulates protein phosphatase 2A by phosphorylation of its B' γsubunit.
Cell Cycle.
2012-02; 11(3): 604-16
Yabuta N, Mukai S, Okada N, Aylon Y, Nojima H. The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis.
Cell Cycle.
2011-08; 10(16): 2724-36
Kaushik G, Ramalingam S, Subramaniam D, Rangarajan P, Protti P, Rammamoorthy P, Anant S, Mammen JM. Honokiol Induces Cytotoxic And Cytostatic Effects In Malignant Melanoma Cancer Cells.
Am J Surg.
2012-12; 204(6): 868-73