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Polyclonal Antibody Production Service
custom polyclonal antibody production service quotation

Custom Polyclonal Antibody Production

GenScript offers a full suite of high quality custom polyclonal antibody production services designed with your needs in mind. Since 2004, our team has produced over 12,000 high quality custom polyclonal antibodies from rabbit, mouse, and rat hosts. The PolyExpress™ protein immunization packages carry industry leading guarantees of positive Western blot and 1:64,000 ELISA titer. All you need to provide is your target sequence and GenScript gets to work. Read More »

Key Features of PolyExpress™ Custom Polyclonal Antibody Production Services

  • Cost effective and comprehensive: pricing starts from $649 and includes antigen synthesis and purification!
  • Fast turnaround time: delivery of purified custom polyclonal antibodies in as little as 45 days.
  • Optimal immunization: Our OptimumAntigen™ design tool and intelligent Antigen Strategy increase specificity and affinity of antibodies.
  • Guaranteed results: affinity purified custom polyclonal antibody quantities and ELISA titers of 1:64,000.
  • Certified facility: AAALAC International accreditation and OLAW certification, demonstrating our commitment to responsible animal care and use.

  • PolyExpress™ Packages
  • PolyExpress™ Service
  • Application Guide
  • Selection Guide
  • Citations and Experimental Data

PolyExpress™ Custom Polyclonal Antibody Production Packages

Protein antigen
Gold Plus
PolyExpress™ Premium
PolyExpress™ Premium Plus
Use recombinant protein as antigen**
protein antigen polyclonal antibodies
40 ml antiserum
40 ml antiserum
2 affinity-purified pAb (0.5-3mg each) and 200 ug protein antigen
affinity-purified pAb
1 affinity-purified pAb (1-5mg) and 1mg protein antigen
affinity-purified pAb
Guaranteed to Perform in Antigen Western Blot and ELISA applications
Peptide antigen
Uses 1 peptide to make antibody

peptide antigen polyclonal antibodies
Uses 2 peptides to make antibodies

peptide antigen polyclonal antibodies
Uses 3 peptides to make antibodies

peptide antigen polyclonal antibodies
1 Ab generated against 1 epitope
peptide antigen polyclonal antibodies
2 Abs generated against 2 individual epitopes
peptide antigen polyclonal antibodiespeptide antigen polyclonal antibodies
3 Abs generated against 3 individual epitopes
peptide antigen polyclonal antibodiespeptide antigen polyclonal antibodiespeptide antigen polyclonal antibodies
Guaranteed 1-5 mg purified antibody
2 affinity-purified antibodies
(1-5 mg/each)
3 affinity-purified antibodies
(1-5 mg/each)
Application Success Rate
Application Success Rate

* Silver and Gold packages only apply to a single target protein sequence. Cannot be combined from different protein targets.
**Protein may be full length or a protein fragment ≥ 10 KD depending on which is more likely to generate a successful antibody.

Details of PolyExpress™ Custom Polyclonal Antibody Production Services

Feature Details Basic
Gold Plus
Premium (SC1676) Premium Plus
Immunization Antigen(s) Synthesized 1
Rabbits Immunized 2 4
(2 per peptide)
(2 per peptide)
1 2
Deliverables Pre-immune Serum 0.5 ml
Quality Control Full data and Mass Spectrometry & HPLC Report of Antigen(s)
Antigen Sample 2 mg of Each Peptide Antigen None 200 µg Protein 1 mg
Antigen Affinity
Purified pAb(s)
(1-5 mg total)
(2-10 mg total)
(3-15 mg total)
None 2
(1-5 mg total)
(1-5mg total)
Guarantee Application ELISA Titer 1:64,000 Positive Western Blot for Antigen
& ELISA titer 1:64,000
Antibody Yields 1 purified pAb
(1-5 mg)
2 purified pAb
(1-5 mg each) 
3 purified pAb
(1-5 mg each)
40ml Serum 2 purified pAb
(0.5-3 mg each)
1 purified pAb
Timeline 45 Days 12 Weeks
Price Base Package Starting from $649 Starting from $1,999

*Each package only applies to a single protein sequence
**GenScript provides peptide synthesis, peptide design, carrier conjugation and antibody purification for free

Assays Western Blot Sandwich ELISA IF, IHC,
Flow Cytometry
Requirements&Rating Rationale
  • Average affinity and specific recognition.
  • High specificity and sensitivity.
  • Ability to use same pAb as both capture and detection.
  • High specificity and sensitivity
  • Conformational epitope recognition
  • Recognize multiple epitopes
    • recovers more target
    • overcomes obscured epitopes
  • Conformational epitope recognition
Premium Plus
Gold Plus
what is your priority

Customer case study

Western blot analyses were performed to measure the effect of the Osi21 functional loss on the degradation of endocytosed rhodopsin.

Cost-effective Custom Polyclonal Antibodies Services

The polyclonal rabbit antiarrestin2 antibody is diluted 1:30,000. (GenScript, NY)

J Lee, M Song, S Hong. Negative Regulation of the Novel norpAP24 Suppressor, diehard4, in the Endo-lysosomal Trafficking Underlies Photoreceptor Cell Degeneration. PLoS Genet. June 2013, 9, e1003559

See Full List of Citations »

Experimental Data

Antibodies produced using PolyExpress™ have ELISA titers as high as polyclonal antibodies produced using a traditional protocol.


ELISA analysis of purified antibody generated by either PolyExpress™ protocol or traditional protocol.

ELISA titer guaranteed custom polyclonal antibody services

ELISA analysis of purified antibody generated by PolyExpress™ Antibody Service.
PolyExpress™ generated an antibody with ELISA titer> 1: 256,000 which is higher than guaranteed.

Polyclonal Antibody Services Recommendations

For polyclonal antibodies targeting poorly defined epitopes we recommend protein antigens. Protein antigens provide the immune system the complete profile of exposed epitopes in the same conformational context the antibody will ultimately recognize the antigen such as FACS, sandwich ELISA, or receptor blocking for example. If financial constraints prevent selection of protein antigen packages, we recommend using the maximum amount of peptide antigens with our Gold package. Read More »

Custom Polyclonal Antibody Generation Related Services

Not looking for polyclonal antibodies? We have offerings for every antibody project. Just a few include:

custom polyclonal antibody production service quotation

Quotation and Ordering

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